Grundlagenforschung

Laufende Projekte

• ASSET – Analysing and Striking the Sensitivities of Embryonal Tumours (EU-FP7 gefördertes Systembiologieprojekt #259348).
• EWS/EWS-FLI1 in der post-transkriptionellen Genregulation (FWF  20665-B12).
• Mechanismen der transkriptionellen Kontrolle durch EWS-FLI1 (FWF 22328-B09).
• Mechanisms of target regulation by the chimeric oncogene EWS-FLI1 in Ewing´s sarcoma (ÖAW DOC-FORTE 22882).
• Präklinische Entwicklung neuer experimenteller Osteosarkom-Therapie anhand experimenteller Gallium-Verbindungen, Zoledronsäure und bone-targeting platinum drugs.
• The EGFR inhibitor Gefitinib sensitizes osteosarcoma cells against anthracycline-based chemotherapy.
• The interplay of NF-KB, HIF-1? and EWS-FLI1 in Ewing’s sarcoma family tumors” (ÖNB 14205).
• Unraveling the mechanisms of resistance to Hedgehog pathway inhibitors in chondrosarcoma.