Klinische Studien

Laufende klinische Studien

• A phase 2, double-blind, placebo-controlled study evaluating the safty and efficacy of IPI-926 in patients with metastatic or locally advanced (unresectable) chondrosarcoma.


• A randomized, double-blind, placebo-controlled phase III study of regorafenib plus best supportive care versus placebo plus best supportive care for subjects with metastatic and/or unresectable gastrointestinal stroma tumors (GIST) whose disease  has progressed despite prior treatment with at least imatinib and sunitinib.


• A randomized, open-label, multi-center phase III study to evaluate the efficacy and safety of nilotinib versus imatinib in adult patients with unresectable or metastatic gastrointestinal stromal tumors (GIST).


• A randomized, open-label, multicenter, phase III study to compare the efficacy and safety of eribulin with dacarbazine in subjects with soft tissue sarcoma.


• An open label, multi-center, phase 2 study of Denosumab in subjects with giant cell tumor of bone. (Recruiting closed!)


• CWS-2007-HR – Randomisiere Phase-III-Studie der Cooperativen Weichteilsarkom Studien-gruppe für lokalisierte Hochrisiko-Rhabdomyosarkome und lokalisierte rhabdomyosarkomartige Weichteiltumore bei Kindern, Jugendlichen und jungen Erwachsenen (EudraCT 2007-001478-10).


• CWS-SoTiSaR – Register für Weichteilsarkome und seltene Weichteiltumore.


• Determination of prognostic MRI features, and evaluation of chemotherapy response in primary malignant bone tumours by MRI, compared to 18-F-FDG-PET/CT.


• Efficacy, safety and tolerability of adjuvant Glivec® (Imatinib) in adult GIST patients within the approved label in Austria.


• EURAMOS 1 – A randomized trial of the European and American Osteosarcoma Study Group to optimize treatment strategies for resectable osteosarcoma based on histological response to pre-operative chemotherapy (Rekrutierung beendet am 30.06.2011).


• EWING 2008 – Ewing Tumoren, prospektive, randomisierte, internationale, multizentrische Phase 3 Studie (EudraCT 2008-003658-13).


• Histologische Analyse von Immunozyten in Osteosarkomen.


• Knochendichte und Frakturrate bei langzeitüberlebenden Ewingsarkompatienten.


• Kooperation im Rahmen des internationalen Tumorprothesenregisters.


• LCH III – Langerhanszell Histiozytose, Therapieoptimierungsstudie.


• Navigationsassistierte Resektion von Knochentumoren.


• Retrospektive klinische Studien von Tumoren des Bewegungsapparates im Rahmen des Wiener Knochen- und Weichteilgeschwulstregisters.


• T2-mapping chondrogener Tumore.


• TRUST: A phase IIb/III multicenter study comparing the efficacy of Trabectedin administered as a 3-hour or 24-hour infusion to doxorubicin in patients with advanced or  metastastic untreated soft tissue sarcoma.