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Collaborative Efforts Driving Progress in Pediatric Acute Myeloid Leukemia. |
Zwaan CM, Kolb EA, Reinhardt D, Abrahamsson J, Adachi S, Aplenc R, De Bont ES, De Moerloose B, Dworzak M, Gibson BE, Hasle H, Leverger G, Locatelli F, Ragu C, Ribeiro RC, Rizzari C, Rubnitz JE, Smith OP, Sung L, Tomizawa D, van den Heuvel-Eibrink MM, Creutzig U, Kaspers GJ |
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2015 Aug 24. pii: JCO.2015.62.8289. doi: 10.1200/JCO.2015.62.8289 |
PMID: 26304895 |
Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study. |
Inaba H, Zhou Y, Abla O, Adachi S, Auvrignon A, Beverloo HB, de Bont E, Chang TT, Creutzig U, Dworzak M, Elitzur S, Fynn A, Forestier E, Hasle H, Liang DC, Lee V, Locatelli F, Masetti R, De Moerloose B, Reinhardt D, Rodriguez L, Van Roy N, Shen S, Taga T, Tomizawa D, Yeoh AE, Zimmermann M, Raimondi SC |
Blood. 2015 Jul 27. pii: blood-2015-02-629204. doi: 10.1182/blood-2015-02-629204 |
PMID: 26215111 |
Bridging to transplant with azacitidine in juvenile myelomonocytic leukemia: a retrospective analysis of the EWOG-MDS study group. |
Cseh A, Niemeyer CM, Yoshimi A, Dworzak M, Hasle H, van den Heuvel-Eibrink MM, Locatelli F, Masetti R, Schmugge M, Groß-Wieltsch U, Candás A, Kulozik AE, Olcay L, Suttorp M, Furlan I, Strahm B, Flotho C |
Blood. 2015 Apr 3. pii: 125/14/2311. doi: 10.1182/blood-2015-01-619734 |
PMID: 25838281 |
Criteria for evaluating response and outcome in clinical trials for children with juvenile myelomonocytic leukemia. |
Niemeyer CM, Loh ML, Cseh A, Cooper T, Dvorak CC, Chan R, Xicoy B, Germing U, Kojima S, Manabe A, Dworzak M, De Moerloose B, Starý J, Smith OP, Masetti R, Catala A, Bergstraesser E, Ussowicz M, Fabri O, Baruchel A, Cavé H, Zwaan M, Locatelli F, Hasle H, van den Heuvel-Eibrink MM, Flotho C, Yoshimi A |
Haematologica. 2015 Jan 1. pii: haematol.2014.109892. doi: 10.3324/haematol.2014.109892. pmc: PMC4281308 |
PMID: 25552679 |
RASA4 undergoes DNA hypermethylation in resistant juvenile myelomonocytic leukemia. |
Poetsch AR, Lipka DB, Witte T, Claus R, Nöllke P, Zucknick M, Olk-Batz C, Fluhr S, Dworzak M, De Moerloose B, Starý J, Zecca M, Hasle H, Schmugge M, van den Heuvel-Eibrink MM, Locatelli F, Niemeyer CM, Flotho C, Plass C |
Epigenetics. 2014 Jul 31. pii: 29941. doi: 10.4161/epi.29941. pmc: PMC4169017 |
PMID: 25147919 |
T-cell receptor Vβ skewing frequently occurs in refractory cytopenia of childhood and is associated with an expansion of effector cytotoxic T cells: a prospective study by EWOG-MDS. |
Aalbers AM, van den Heuvel-Eibrink MM, Baumann I, Beverloo HB, Driessen GJ, Dworzak M, Fischer A, Göhring G, Hasle H, Locatelli F, De Moerloose B, Noellke P, Schmugge M, Stary J, Yoshimi A, Zecca M, Zwaan CM, van Dongen JJ, Pieters R, Niemeyer CM, van der Velden VH, Langerak AW |
Blood cancer journal. 2014 May 2. pii: bcj201428. doi: 10.1038/bcj.2014.28. pmc: PMC4042298 |
PMID: 24786393 |
The prognostic significance of early treatment response in pediatric relapsed acute myeloid leukemia: results of the international study Relapsed AML 2001/01. |
Creutzig U, Zimmermann M, Dworzak MN, Gibson B, Tamminga R, Abrahamsson J, Ha SY, Hasle H, Maschan A, Bertrand Y, Leverger G, von Neuhoff C, Razzouk B, Rizzari C, Smisek P, Smith OP, Stark B, Reinhardt D, Kaspers GL |
Haematologica. 2014 Apr 24. pii: haematol.2014.104182. doi: 10.3324/haematol.2014.104182 |
PMID: 24763401 |
The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood: a prospective study by EWOG-MDS. |
Aalbers AM, van der Velden VH, Yoshimi A, Fischer A, Noellke P, Zwaan CM, Baumann I, Beverloo HB, Dworzak M, Hasle H, Locatelli F, De Moerloose B, Göhring G, Schmugge M, Stary J, Zecca M, Langerak AW, van Dongen JJ, Pieters R, Niemeyer CM, van den Heuvel-Eibrink MM |
Leukemia. 2013 Jun 28. pii: leu2013195. doi: 10.1038/leu.2013.195 |
PMID: 23807769 |
Therapy reduction in patients with Down Syndrome Myeloid Leukemia: The international ML-DS 2006 trial. |
Uffmann M, Rasche M, Zimmermann M, von Neuhoff C, Creutzig U, Dworzak M, Scheffers L, Hasle H, Zwaan CM, Reinhardt D, Klusmann JH |
Blood. 2017 Apr 11. pii: blood-2017-01-765057. doi: 10.1182/blood-2017-01-765057 |
PMID: 28400376 |
Characteristics and outcome in patients with central nervous system involvement treated in European pediatric acute myeloid leukemia study groups. |
Creutzig U, Dworzak MN, Zimmermann M, Reinhardt D, Sramkova L, Bourquin JP, Hasle H, Abrahamsson J, Kaspers G, van den Heuvel MM, Reedijk AMJ, De Moerloose B, Locatelli F, Masetti R |
Pediatric blood & cancer. 2017 Jun 9. doi: 10.1002/pbc.26664 |
PMID: 28598536 |
RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia. |
Lipka DB, Witte T, Toth R, Yang J, Wiesenfarth M, Nöllke P, Fischer A, Brocks D, Gu Z, Park J, Strahm B, Wlodarski M, Yoshimi A, Claus R, Lübbert M, Busch H, Boerries M, Hartmann M, Schönung M, Kilik U, Langstein J, Wierzbinska JA, Pabst C, Garg S, Catalá A, De Moerloose B, Dworzak M, Hasle H, Locatelli F, Masetti R, Schmugge M, Smith O, Stary J, Ussowicz M, van den Heuvel-Eibrink MM, Assenov Y, Schlesner M, Niemeyer C, Flotho C, Plass C |
Nature communications. 2017 Dec 19. doi: 10.1038/s41467-017-02177-w. pii: 10.1038/s41467-017-02177-w |
PMID: 29259247 |
Outcome of children relapsing after first allogeneic haematopoietic stem cell transplantation for acute myeloid leukaemia: a retrospective I-BFM analysis of 333 children. |
Uden T, Bertaina A, Abrahamsson J, Ansari M, Balduzzi A, Bourquin JP, Gerhardt C, Bierings M, Hasle H, Lankester A, Mischke K, Moore AS, Nivison-Smith I, Pieczonka A, Peters C, Sedlacek P, Reinhardt D, Stein J, Versluys B, Wachowiak J, Willems L, Zimmermann M, Locatelli F, Sauer MG |
British journal of haematology. 2020 Feb 3. doi: 10.1111/bjh.16441 |
PMID: 32012224 |
Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency. |
Kozyra EJ, Pastor VB, Lefkopoulos S, Sahoo SS, Busch H, Voss RK, Erlacher M, Lebrecht D, Szvetnik EA, Hirabayashi S, Pasaulienė R, Pedace L, Tartaglia M, Klemann C, Metzger P, Boerries M, Catala A, Hasle H, de Haas V, Kállay K, Masetti R, De Moerloose B, Dworzak M, Schmugge M, Smith O, Starý J, Mejstrikova E, Ussowicz M, Morris E, Singh P, Collin M, Derecka M, Göhring G, Flotho C, Strahm B, Locatelli F, Niemeyer CM, Trompouki E, Wlodarski MW |
Leukemia. 2020 Jun 18. doi: 10.1038/s41375-020-0899-5. pii: 10.1038/s41375-020-0899-5 |
PMID: 32555368 |
Hematopoietic stem cell transplantation in children and adolescents with GATA2-related myelodysplastic syndrome. |
Bortnick R, Wlodarski M, de Haas V, De Moerloose B, Dworzak M, Hasle H, Masetti R, Starý J, Turkiewicz D, Ussowicz M, Kozyra E, Albert M, Bader P, Bordon V, Cario G, Beier R, Schulte J, Bresters D, Müller I, Pichler H, Sedlacek P, Sauer MG, Zecca M, Göhring G, Yoshimi A, Noellke P, Erlacher M, Locatelli F, Niemeyer CM, Strahm B |
Bone marrow transplantation. 2021 Jul 9. doi: 10.1038/s41409-021-01374-y. pii: 10.1038/s41409-021-01374-y |
PMID: 34244664 |
Prognostic significance of chromosomal abnormalities at relapse in children with relapsed acute myeloid leukemia: A retrospective cohort study of the Relapsed AML 2001/01 Study. |
Klein K, Beverloo HB, Zimmermann M, Raimondi SC, von Neuhoff C, de Haas V, van Weelderen R, Cloos J, Abrahamsson J, Bertrand Y, Dworzak M, Fynn A, Gibson B, Ha SY, Harrison CJ, Hasle H, Elitzur S, Leverger G, Maschan A, Razzouk B, Reinhardt D, Rizzari C, Smisek P, Creutzig U, Kaspers GJL |
Pediatric blood & cancer. 2021 Sep 17. doi: 10.1002/pbc.29341 |
PMID: 34532968 |
Publisher Correction: Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes. |
Sahoo SS, Pastor VB, Goodings C, Voss RK, Kozyra EJ, Szvetnik A, Noellke P, Dworzak M, Starý J, Locatelli F, Masetti R, Schmugge M, De Moerloose B, Catala A, Kállay K, Turkiewicz D, Hasle H, Buechner J, Jahnukainen K, Ussowicz M, Polychronopoulou S, Smith OP, Fabri O, Barzilai S, de Haas V, Baumann I, Schwarz-Furlan S, Niewisch MR, Sauer MG, Burkhardt B, Lang P, Bader P, Beier R, Müller I, Albert MH, Meisel R, Schulz A, Cario G, Panda PK, Wehrle J, Hirabayashi S, Derecka M, Durruthy-Durruthy R, Göhring G, Yoshimi-Noellke A, Ku M, Lebrecht D, Erlacher M, Flotho C, Strahm B, Niemeyer CM, Wlodarski MW |
Nature medicine. 2021 Nov 19. doi: 10.1038/s41591-021-01632-y. pii: 10.1038/s41591-021-01632-y |
PMID: 34799732 |
Guideline for management of non-Down syndrome neonates with a myeloproliferative disease on behalf of the I-BFM AML Study Group and EWOG-MDS. |
Bertrums EJM, Zwaan CM, Hasegawa D, De Haas V, Reinhardt DN, Locatelli F, De Moerloose B, Dworzak M, Buijs A, Smisek P, Kolenova A, Pronk CJ, Klusmann JH, Carboné A, Ferster A, Antoniou E, Meshinchi S, Raimondi SC, Niemeyer CM, Hasle H, Van den Heuvel-Eibrink MM, Goemans BF |
Haematologica. 2021 Dec 2. doi: 10.3324/haematol.2021.279507 |
PMID: 34854279 |
Comprehensive molecular and clinical characterization of NUP98 fusions in pediatric acute myeloid leukemia. |
Bertrums EJM, Smith JL, Harmon L, Ries RE, Wang YJ, Alonzo TA, Menssen AJ, Chisholm KM, Leonti AR, Tarlock K, Ostronoff F, Pogosova-Agadjanyan EL, Kaspers GJL, Hasle H, Dworzak M, Walter C, Muhlegger N, Morerio C, Pardo L, Hirsch B, Raimondi S, Cooper TM, Aplenc R, Gamis AS, Kolb EA, Farrar JE, Stirewalt D, Ma X, Shaw TI, Furlan SN, Brodersen LE, Loken MR, Van den Heuvel-Eibrink MM, Zwaan CM, Triche TJ, Goemans BF, Meshinchi S |
Haematologica. 2023 Feb 23. doi: 10.3324/haematol.2022.281653 |
PMID: 36815378 |
Second allogeneic stem cell transplantation can rescue a significant proportion of patients with JMML relapsing after first allograft. |
Vinci L, Flotho C, Noellke P, Lebrecht D, Masetti R, de Haas V, De Moerloose B, Dworzak M, Hasle H, Güngör T, Starý J, Turkiewicz D, Ussowicz M, de Heredia CD, Buechner J, Jahnukainen K, Kallay K, Bodova I, Smith OP, Zecca M, Bresters D, Lang P, Masmas TN, Meisel R, Pichler H, Erlacher M, Göhring G, Locatelli F, Strahm B, Niemeyer CM, Yoshimi A |
Bone marrow transplantation. 2023 Feb 23. doi: 10.1038/s41409-023-01942-4. pii: 10.1038/s41409-023-01942-4 |
PMID: 36823455 |
Measurable Residual Disease and Fusion Partner Independently Predict Survival and Relapse Risk in Childhood -Rearranged Acute Myeloid Leukemia: A Study by the International Berlin-Frankfurt-Münster Study Group. |
van Weelderen RE, Klein K, Harrison CJ, Jiang Y, Abrahamsson J, Arad-Cohen N, Bart-Delabesse E, Buldini B, De Moerloose B, Dworzak MN, Elitzur S, Fernández Navarro JM, Gerbing RB, Goemans BF, de Groot-Kruseman HA, Guest E, Ha SY, Hasle H, Kelaidi C, Lapillonne H, Leverger G, Locatelli F, Masetti R, Miyamura T, Norén-Nyström U, Polychronopoulou S, Rasche M, Rubnitz JE, Stary J, Tierens A, Tomizawa D, Zwaan CM, Kaspers GJL |
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2023 Mar 30. doi: 10.1200/JCO.22.02120 |
PMID: 36996387 |
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