Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2015 Mar 31. pii: S1083-8791(15)00224-4. doi: 10.1016/j.bbmt.2015.03.024 |
National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: V. The 2014 Ancillary Therapy and Supportive Care Working Group Report. |
Carpenter PA1, Kitko CL2, Elad S3, Flowers ME4, Gea-Banacloche JC5, Halter JP6, Hoodin F7, Johnston L8, Lawitschka A9, McDonald GB10, Opipari AW11, Savani BN12, Schultz KR13, Smith SR14, Syrjala KL15, Treister N16, Vogelsang GB17, Williams KM18, Pavletic SZ19, Martin PJ20, Lee SJ21, Couriel DR22 |
Abstract The 2006 National Institutes of Health (NIH) Consensus paper presented recommendations by the Ancillary Therapy and Supportive Care Working Group to support clinical research trials in chronic graft-versus-host disease (GVHD). Topics covered in that inaugural effort included the prevention and management of infections and common complications of chronic GVHD, as well as recommendations for patient education and appropriate follow-up. Given the new literature that has emerged during the past 8 years, we made further organ-specific refinements to these guidelines. Minimum frequencies are suggested for monitoring key parameters relevant to chronic GVHD during systemic immunosuppressive therapy and, thereafter, referral to existing late effects consensus guidelines is advised. Using the framework of the prior consensus, the 2014 NIH recommendations are organized by organ or other relevant systems and graded according to the strength and quality of supporting evidence. |
Copyright © 2015 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved. |
KEYWORDS: Allogeneic hematopoietic cell transplantation, Chronic graft-versus-host disease, Consensus, Guidelines, Supportive care |
Publikations ID: 25838185 Quelle: öffnen |