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    Breast (Edinburgh, Scotland). 2015 Mar 25. pii: S0960-9776(15)00057-0. doi: 10.1016/j.breast.2015.02.031
    Discrepancies between ESMO and NCCN breast cancer guidelines: An appraisal.
    Zagouri F1,  Liakou P2,  Bartsch R3,  Peccatori FA4,  Tsigginou A5,  Dimitrakakis C6,  Zografos GC7,  Dimopoulos MA8,  Azim HA9
    Author information
    1Department of Clinical Therapeutics, Alexandra Hospital, Medical School, University of Athens, Greece.
    21st Propaedeutic Surgical Dept, Hippocrateio Hospital, Medical School, University of Athens, Athens, Greece.
    3Clinical Division of Oncology, Medical University of Vienna, Austria.
    4Department of Obstetrics and Gynecology, Medical School, University of Athens, Greece.
    5Fertility and Procreation Unit, Department of Gynecologic Oncology, European Institute of Oncology, Milan, Italy.
    6Eunice Kennedy Shriver, National Institute of Child Health and Human Development, National Institutes of Health, USA.
    71st Propaedeutic Surgical Dept, Hippocrateio Hospital, Medical School, University of Athens, Athens, Greece.
    8Department of Clinical Therapeutics, Alexandra Hospital, Medical School, University of Athens, Greece.
    9Department of Medicine, BrEAST Data Centre, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium. Electronic address: hatem.azim@bordet.be.
    Abstract

    An ever growing number of medical organizations, societies, working groups and governmental agencies issue algorithms i.e. guidelines, of decision making flowcharts in diagnosis and treatment in a variety of diseases. In the field of evidence-based diagnosis and treatment of breast cancer, a large number of guidelines are available both from medical associations and national health departments. Among the most appreciated and utilized comprehensive guides is the European Society for Medical Oncology (ESMO) Breast Cancer Guidelines and from the other side of the Atlantic the National Comprehensive Cancer Network (NCCN) Guidelines in Breast Cancer. Although there is much concordance between the guidelines from these two organizations, it is intriguing to locate their discrepancies also. The aim of this report is to present a number of different points between ESMO and NCCN in the whole spectrum of breast cancer management, from prevention and diagnosis to treatment and follow up. This systematic review was performed in accordance with the PRISMA guidelines using a predefined search strategy and summarizes in detail, the differences between ESMO and NCCN guidelines regarding genetic risk evaluation and screening, surgery, chemotherapy, endocrine treatment, targeted biological agents, radiotherapy, pregnancy and fertility and follow-up.


    Copyright © 2015 Elsevier Ltd. All rights reserved.

    KEYWORDS: Adjuvant, Breast cancer, ESMO, Guidelines, Metastatic, NCCN

    Publikations ID: 25818651
    Quelle: öffnen
     
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