Aktuell (Grundlagenforschung)

• ALK gene status and protein expression in gastroesophageal adenocarcinomas and squamous cell carcinoma of the esophagus
  
  
• Clinical role of peripheral blood platelets in angiogenesis and lymphangiogenesis of esophageal cancer
  
  
• Evaluation of established prognostic factors as predictive factors for histological and PET-CT assessed response to neoadjuvant chemotherapy in esophageal cancer
  
  
• Molecular profiling of brain metastases in gastroesophageal cancer
  
  
• MAPKAP Kinase 2 and ETV-1 in esophageal cancer and its metastases
  
  
• Next generation exom sequencing of gastrointestinal stromal tumors (Cooperation University of Heidelberg)
  
  
• MicroRNA profiling in esophageal adenocarcinoma and Barrett´s esopahgus
  
  
• Role of MEK1/MEK2 and RAF-kinase inhibitory protein in GIST

Interdisziplinäre und inter-/nationale Kooperationen

• ASSO (Austrian Society of Surgical Oncology)
• NIH/NCI (Division of Cancer Epidemiology and Genetics, Bethesta)
• Universität Heidelberg
• T. Helbich, Small Animal Imaging Unit, Medizinische Universität Wien

Zukünftig (Grundlagenforschung)

• Role of PTEN/PI3K/AKT pathway -activation on neoangiogenesis and cell migration in esophageal cancer
  
  
• Influence of JAK1/JAK2 on phosphorylation of STAT3 in esophagel cancer
  
  
• MicroRNA profiling in esophageal adenocarcinoma and Barrett´s esopahgus
  
  
• Next generation sequencing for detection of clonal evolution of gastro-oesphageal cancer cells during neodjuvant chemotherapy
  
  
• Inhibition of ER81/ MAPKAPK2 pathway in GIST cell lines
  
  
• Ultra deep sequencing for detection of minimal residual disease in gastroesophageal tumors
  
  
• Crizotinib for inhibition of ALK amplificated Upper GI cell lines in vitro
  
  
• HPV status in relation to p16 expression oesophageal cancer
  
  
• Her-Ligands and their interaction with ERBB1 and HER2 in gastro-oesophageal cancer