supplied by www.ccc.ac.at

226 Einträge

Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma.
Autoren Laszlo V, Hoda MA, Garay T, Pirker C, Ghanim B, Klikovits T, Dong YW, Rozsas A, Kenessey I, Szirtes I, Grusch M, Jakopovic M, Samarzija M, Brcic L, Kern I, Rozman A, Popper H, Zöchbauer-Müller S, Heller G, Altenberger C, Ziegler B, Klepetko W, Berger W, Dome B, Hegedus B
Erscheinungsdaten The Journal of pathology. 2015 May 26. doi: 10.1002/path.4567
Publikations ID PMID: 26011651
 


Triapine-mediated ABCB1 induction via PKC induces widespread therapy unresponsiveness but is not underlying acquired triapine resistance.
Autoren Miklos W, Pelivan K, Kowol CR, Pirker C, Dornetshuber-Fleiss R, Spitzwieser M, Englinger B, van Schoonhoven S, Cichna-Markl M, Koellensperger G, Keppler BK, Berger W, Heffeter P
Erscheinungsdaten Cancer letters. 2015 Mar 5. pii: S0304-3835(15)00164-0. doi: 10.1016/j.canlet.2015.02.049
Publikations ID PMID: 25749419
 


Prognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosis.
Autoren Spiegl-Kreinecker S, Lötsch D, Ghanim B, Pirker C, Mohr T, Laaber M, Weis S, Olschowski A, Webersinke G, Pichler J, Berger W
Erscheinungsdaten Neuro-oncology. 2015 Feb 13. pii: nov010. doi: 10.1093/neuonc/nov010
Publikations ID PMID: 25681309
 


Vemurafenib resistance signature by proteome analysis offers new strategies and rational therapeutic concepts.
Autoren Paulitschke V, Berger W, Paulitschke P, Hofstätter E, Knapp B, Dingelmaier-Hovorka R, Födinger D, Jäger W, Szekeres T, Meshcheryakova A, Bileck A, Pirker C, Pehamberger H, Gerner C, Kunstfeld R
Erscheinungsdaten Molecular cancer therapeutics. 2015 Jan 22. pii: 1535-7163.MCT-14-0701. doi: 10.1158/1535-7163.MCT-14-0701
Publikations ID PMID: 25612618
 


Fibroblast growth factor receptor 4: a putative key driver for the aggressive phenotype of hepatocellular carcinoma.
Autoren Gauglhofer C, Paur J, Schrottmaier WC, Wingelhofer B, Huber D, Naegelen I, Pirker C, Mohr T, Heinzle C, Holzmann K, Marian B, Schulte-Hermann R, Berger W, Krupitza G, Grusch M, Grasl-Kraupp B
Erscheinungsdaten Carcinogenesis. 2014 Jul 16. pii: bgu151. doi: 10.1093/carcin/bgu151
Publikations ID PMID: 25031272
 


Impact of terminal dimethylation on the resistance profile of α-N-heterocyclic thiosemicarbazones.
Autoren Heffeter P, Pirker C, Kowol CR, Herrman G, Dornetshuber R, Miklos W, Jungwirth U, Koellensperger G, Keppler BK, Berger W
Erscheinungsdaten Biochemical pharmacology. 2012 Mar 15. pii: S0006-2952(12)00196-7. doi: 10.1016/j.bcp.2012.03.004. pmc: PMC3342514
Publikations ID PMID: 22426010
 


Synergistic effects of erlotinib and everolimus on bronchial carcinoids and large-cell neuroendocrine carcinomas with activated EGFR/AKT/mTOR pathway.
Autoren Bago-Horvath Z, Sieghart W, Grusch M, Lackner A, Hayden H, Pirker C, Komina O, Węsierska-Gądek J, Haitel A, Filipits M, Berger W, Schmid K
Erscheinungsdaten Neuroendocrinology. 2012 Apr 27. pii: 000337257. doi: 10.1159/000337257
Publikations ID PMID: 22378048
 


Fibroblast growth factor receptors as therapeutic targets in human melanoma: synergism with BRAF inhibition.
Autoren Metzner T, Bedeir A, Held G, Peter-Vörösmarty B, Ghassemi S, Heinzle C, Spiegl-Kreinecker S, Marian B, Holzmann K, Grasl-Kraupp B, Pirker C, Micksche M, Berger W, Heffeter P, Grusch M
Erscheinungsdaten The Journal of investigative dermatology. 2011 Jul 14. pii: jid2011177. doi: 10.1038/jid.2011.177. pmc: PMC3383623. mid: UKMS48843
Publikations ID PMID: 21753785
 


DNA damage, somatic aneuploidy, and malignant sarcoma susceptibility in muscular dystrophies.
Autoren Schmidt WM, Uddin MH, Dysek S, Moser-Thier K, Pirker C, Höger H, Ambros IM, Ambros PF, Berger W, Bittner RE
Erscheinungsdaten PLoS genetics. 2011 Apr 14. doi: 10.1371/journal.pgen.1002042. pmc: PMC3077392
Publikations ID PMID: 21533183
 


Overexpression of Aurora-A in primary cells interferes with S-phase entry by diminishing Cyclin D1 dependent activities.
Autoren Jantscher F, Pirker C, Mayer CE, Berger W, Sutterluety H
Erscheinungsdaten Molecular cancer. 2011 Mar 16. pii: 1476-4598-10-28. doi: 10.1186/1476-4598-10-28. pmc: PMC3068985
Publikations ID PMID: 21410931
 


A human model of epithelial to mesenchymal transition to monitor drug efficacy in hepatocellular carcinoma progression.
Autoren van Zijl F, Mall S, Machat G, Pirker C, Zeillinger R, Weinhaeusel A, Bilban M, Berger W, Mikulits W
Erscheinungsdaten Molecular cancer therapeutics. 2011 Mar 1. pii: 1535-7163.MCT-10-0917. doi: 10.1158/1535-7163.MCT-10-0917
Publikations ID PMID: 21364009
 


Response of experimental malignant melanoma models to the pan-Aurora kinase inhibitor VE-465.
Autoren Pirker C, Lötsch D, Spiegl-Kreinecker S, Jantscher F, Sutterlüty H, Micksche M, Grusch M, Berger W
Erscheinungsdaten Experimental dermatology. 2010 Nov 22. doi: 10.1111/j.1600-0625.2010.01182.x
Publikations ID PMID: 21087322
 


EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases.
Autoren Schmid K, Oehl N, Wrba F, Pirker R, Pirker C, Filipits M
Erscheinungsdaten Clinical cancer research : an official journal of the American Association for Cancer Research. 2009 Jul 7. pii: 1078-0432.CCR-09-0089. doi: 10.1158/1078-0432.CCR-09-0089
Publikations ID PMID: 19584155
 


Simultaneous blockade of the epidermal growth factor receptor/mammalian target of rapamycin pathway by epidermal growth factor receptor inhibitors and rapamycin results in reduced cell growth and survival in biliary tract cancer cells.
Autoren Herberger B, Berger W, Puhalla H, Schmid K, Novak S, Brandstetter A, Pirker C, Gruenberger T, Filipits M
Erscheinungsdaten Molecular cancer therapeutics. 2009 Jun 9. pii: 1535-7163.MCT-09-0003. doi: 10.1158/1535-7163.MCT-09-0003
Publikations ID PMID: 19509244
 


Synergistic effect of Sorafenib and Sunitinib with Enzastaurin, a selective protein kinase C inhibitor in renal cell carcinoma cell lines.
Autoren Vogl UM, Berger W, Micksche M, Pirker C, Lamm W, Pichelmeyer O, Zielinski CC, Schmidinger M
Erscheinungsdaten Cancer letters. 2009 Jan 25. pii: S0304-3835(08)00945-2. doi: 10.1016/j.canlet.2008.12.013
Publikations ID PMID: 19171421
 


Multidrug-resistant cancer cells are preferential targets of the new antineoplastic lanthanum compound KP772 (FFC24).
Autoren Heffeter P, Jakupec MA, Körner W, Chiba P, Pirker C, Dornetshuber R, Elbling L, Sutterlüty H, Micksche M, Keppler BK, Berger W
Erscheinungsdaten Biochemical pharmacology. 2007 Mar 12. pii: S0006-2952(07)00146-3. doi: 10.1016/j.bcp.2007.03.002. pmc: PMC3371634. mid: UKMS48675
Publikations ID PMID: 17445775
 


Malignant predominantly minigemistocytic glioma in two infants: a distinctive glioma variant?
Autoren Haberler C, Slavc I, Czech T, Prayer D, Pirker C, Budka H, Hainfellner JA
Erscheinungsdaten Neuropathology and applied neurobiology. 2007 Mar 15. pii: NAN823. doi: 10.1111/j.1365-2990.2006.00823.x
Publikations ID PMID: 17359358
 


Telomerase- and alternative telomere lengthening-independent telomere stabilization in a metastasis-derived human non-small cell lung cancer cell line: effect of ectopic hTERT.
Autoren Brachner A, Sasgary S, Pirker C, Rodgarkia C, Mikula M, Mikulits W, Bergmeister H, Setinek U, Wieser M, Chin SF, Caldas C, Micksche M, Cerni C, Berger W
Erscheinungsdaten Cancer research. 2006 Apr 4. pii: 66/7/3584. doi: 10.1158/0008-5472.CAN-05-2839
Publikations ID PMID: 16585183
 


The major vault protein is responsive to and interferes with interferon-gamma-mediated STAT1 signals.
Autoren Steiner E, Holzmann K, Pirker C, Elbling L, Micksche M, Sutterlüty H, Berger W
Erscheinungsdaten Journal of cell science. 2006 Jan 17. pii: jcs.02773. doi: 10.1242/jcs.02773
Publikations ID PMID: 16418217
 


Seven novel and stable translocations associated with oncogenic gene expression in malignant melanoma.
Autoren Okamoto I, Pirker C, Bilban M, Berger W, Losert D, Marosi C, Haas OA, Wolff K, Pehamberger H
Erscheinungsdaten Neoplasia (New York, N.Y.). 2005 Jun 21. pmc: PMC1501156
Publikations ID PMID: 15967107
 


EGFR is not a major driver for osteosarcoma cell growth in vitro but contributes to starvation and chemotherapy resistance.
Autoren Sevelda F, Mayr L, Kubista B, Lötsch D, van Schoonhoven S, Windhager R, Pirker C, Micksche M, Berger W
Erscheinungsdaten Journal of experimental & clinical cancer research : CR. 2015 Nov 2. doi: 10.1186/s13046-015-0251-5. pii: 10.1186/s13046-015-0251-5. pmc: PMC4630894
Publikations ID PMID: 26526352
 


Opposing roles of JNK and p38 in lymphangiogenesis in melanoma.
Autoren Puujalka E, Heinz M, Hoesel B, Friedl P, Schweighofer B, Wenzina J, Pirker C, Schmid JA, Loewe R, Wagner EF, Berger W, Petzelbauer P
Erscheinungsdaten The Journal of investigative dermatology. 2016 Jan 29. pii: S0022-202X(16)00374-2. doi: 10.1016/j.jid.2016.01.020
Publikations ID PMID: 26829032
 


Chronic arsenic trioxide exposure leads to enhanced aggressiveness via Met oncogene addiction in cancer cells.
Autoren Kryeziu K, Pirker C, Englinger B, van Schoonhoven S, Spitzwieser M, Mohr T, Körner W, Weinmüllner R, Tav K, Grillari J, Cichna-Markl M, Berger W, Heffeter P
Erscheinungsdaten Oncotarget. 2016 Mar 28. pii: 8415. doi: 10.18632/oncotarget.8415
Publikations ID PMID: 27036042
 


Anticancer metal drugs and immunogenic cell death.
Autoren Terenzi A, Pirker C, Keppler BK, Berger W
Erscheinungsdaten Journal of inorganic biochemistry. 2016 Jun 16. pii: S0162-0134(16)30184-2. doi: 10.1016/j.jinorgbio.2016.06.021
Publikations ID PMID: 27350082
 


Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expression.
Autoren Englinger B, Lötsch D, Pirker C, Mohr T, van Schoonhoven S, Boidol B, Lardeau CH, Spitzwieser M, Szabó P, Heffeter P, Lang I, Cichna-Markl M, Grasl-Kraupp B, Marian B, Grusch M, Kubicek S, Szakács G, Berger W
Erscheinungsdaten Oncotarget. 2016 Jun 29. pii: 10324. doi: 10.18632/oncotarget.10324
Publikations ID PMID: 27367030
 


Trabectedin is active against malignant pleural mesothelioma cell and xenograft models and synergizes with chemotherapy and bcl-2 inhibition in vitro.
Autoren Hoda MA, Pirker C, Dong Y, Schelch K, Heffeter P, Kryeziu K, van Schoonhoven S, Klikovits T, Laszlo V, Rozsas A, Ozsvar J, Klepetko W, Doeme B, Grusch M, Hegedues B, Berger W
Erscheinungsdaten Molecular cancer therapeutics. 2016 Aug 10. pii: 1535-7163.MCT-15-0846. doi: 10.1158/1535-7163.MCT-15-0846
Publikations ID PMID: 27512118
 


Loss of phosphodiesterase 4D mediates acquired triapine resistance via Epac-Rap1-Integrin signaling.
Autoren Miklos W, Heffeter P, Pirker C, Hager S, Kowol CR, Schoonhoven SV, Stojanovic M, Keppler BK, Berger W
Erscheinungsdaten Oncotarget. 2016 Sep 2. pii: 11821. doi: 10.18632/oncotarget.11821
Publikations ID PMID: 27602951
 


Promoter methylation patterns of ABCB1, ABCC1 and ABCG2 in human cancer cell lines, multidrug-resistant cell models and tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients.
Autoren Spitzwieser M, Pirker C, Koblmüller B, Pfeiler G, Hacker S, Berger W, Heffeter P, Cichna-Markl M
Erscheinungsdaten Oncotarget. 2016 Sep 28. pii: 12332. doi: 10.18632/oncotarget.12332
Publikations ID PMID: 27689338
 


Loss of CUL4A expression is underlying cisplatin hypersensitivity in colorectal carcinoma cells with acquired trabectedin resistance.
Autoren Englinger B, Mair M, Miklos W, Pirker C, Mohr T, van Schoonhoven S, Lötsch D, Körner W, Ferk F, Knasmüller S, Heffeter P, Keppler BK, Grusch M, Berger W
Erscheinungsdaten British journal of cancer. 2017 Jan 17. pii: bjc2016449. doi: 10.1038/bjc.2016.449
Publikations ID PMID: 28095394
 


[(11)C]Erlotinib PET cannot detect acquired erlotinib resistance in NSCLC tumor xenografts in mice.
Autoren Traxl A, Beikbaghban T, Wanek T, Kryeziu K, Pirker C, Mairinger S, Stanek J, Filip T, Sauberer M, Kuntner C, Berger W, Langer O
Erscheinungsdaten Nuclear medicine and biology. 2017 May 25. pii: S0969-8051(17)30117-8. doi: 10.1016/j.nucmedbio.2017.05.007
Publikations ID PMID: 28575795
 


Sensitivity towards the GRP78 inhibitor KP1339/IT-139 is characterized by apoptosis induction via caspase 8 upon disruption of ER homeostasis.
Autoren Schoenhacker-Alte B, Mohr T, Pirker C, Kryeziu K, Kuhn PS, Buck A, Hofmann T, Gerner C, Hermann G, Koellensperger G, Keppler BK, Berger W, Heffeter P
Erscheinungsdaten Cancer letters. 2017 Jul 14. pii: S0304-3835(17)30435-4. doi: 10.1016/j.canlet.2017.07.009
Publikations ID PMID: 28716523
 


Intrinsic fluorescence of the clinically approved multikinase inhibitor nintedanib reveals lysosomal sequestration as resistance mechanism in FGFR-driven lung cancer.
Autoren Englinger B, Kallus S, Senkiv J, Heilos D, Gabler L, van Schoonhoven S, Terenzi A, Moser P, Pirker C, Timelthaler G, Jäger W, Kowol CR, Heffeter P, Grusch M, Berger W
Erscheinungsdaten Journal of experimental & clinical cancer research : CR. 2017 Sep 7. doi: 10.1186/s13046-017-0592-3. pii: 10.1186/s13046-017-0592-3
Publikations ID PMID: 28882160
 


Intrathoracic solitary fibrous tumor - an international multicenter study on clinical outcome and novel circulating biomarkers.
Autoren Ghanim B, Hess S, Bertoglio P, Celik A, Bas A, Oberndorfer F, Melfi F, Mussi A, Klepetko W, Pirker C, Berger W, Harmati I, Farkas A, Jan Ankersmit H, Dome B, Fillinger J, Aigner C, Hegedus B, Renyi-Vamos F, Lang G
Erscheinungsdaten Scientific reports. 2017 Oct 2. doi: 10.1038/s41598-017-12914-2. pii: 10.1038/s41598-017-12914-2
Publikations ID PMID: 28970578
 


Dysregulated expression of the microRNA miR-137 and its target YB-1 contribute to the invasive characteristics of malignant pleural mesothelioma.
Autoren Johnson TG, Schelch K, Cheng YY, Williams M, Sarun KH, Kirschner MB, Kao S, Linton A, Klebe S, McCaughan BC, Lin RC, Pirker C, Berger W, Lasham A, van Zandwijk N, Reid G
Erscheinungsdaten Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2017 Nov 4. pii: S1556-0864(17)32860-5. doi: 10.1016/j.jtho.2017.10.016
Publikations ID PMID: 29113949
 


FGF5 is expressed in melanoma and enhances malignancy in vitro and in vivo.
Autoren Ghassemi S, Vejdovszky K, Sahin E, Ratzinger L, Schelch K, Mohr T, Peter-Vörösmarty B, Brankovic J, Lackner A, Leopoldi A, Meindl D, Pirker C, Hegedus B, Marian B, Holzmann K, Grasl-Kraupp B, Heffeter P, Berger W, Grusch M
Erscheinungsdaten Oncotarget. 2017 Sep 23. doi: 10.18632/oncotarget.21184. pii: 21184. pmc: PMC5675669
Publikations ID PMID: 29152117
 


CD44 drives aggressiveness and chemoresistance of a metastatic human osteosarcoma xenograft model.
Autoren Mayr L, Pirker C, Lötsch D, Van Schoonhoven S, Windhager R, Englinger B, Berger W, Kubista B
Erscheinungsdaten Oncotarget. 2017 Dec 9. doi: 10.18632/oncotarget.23125. pii: 23125. pmc: PMC5768389
Publikations ID PMID: 29371972
 


Dynamics of CRISPR/Cas9-mediated genomic editing of the AXL locus in hepatocellular carcinoma cells.
Autoren Scharf I, Bierbaumer L, Huber H, Wittmann P, Haider C, Pirker C, Berger W, Mikulits W
Erscheinungsdaten Oncology letters. 2017 Dec 13. doi: 10.3892/ol.2017.7605. pii: OL-0-0-7605. pmc: PMC5777348
Publikations ID PMID: 29434956
 


FGF2 and EGF induce epithelial-mesenchymal transition in malignant pleural mesothelioma cells via a MAPKinase/MMP1 signal.
Autoren Schelch K, Wagner C, Hager S, Pirker C, Siess K, Lang E, Lin R, Kirschner MB, Mohr T, Brcic L, Marian B, Holzmann K, Grasl-Kraupp B, Krupitza G, Laszlo V, Klikovits T, Dome B, Hegedus B, Garay T, Reid G, van Zandwijk N, Klepetko W, Berger W, Grusch M, Hoda MA
Erscheinungsdaten Carcinogenesis. pii: 4904272. doi: 10.1093/carcin/bgy018
Publikations ID PMID: 29635378
 


Bacterial ghosts as adjuvant to oxaliplatin chemotherapy in colorectal carcinomatosis.
Autoren Groza D, Gehrig S, Kudela P, Holcmann M, Pirker C, Dinhof C, Schueffl HH, Sramko M, Hoebart J, Alioglu F, Grusch M, Ogris M, Lubitz W, Keppler BK, Pashkunova-Martic I, Kowol CR, Sibilia M, Berger W, Heffeter P
Erscheinungsdaten Oncoimmunology. 2018 Feb 16. doi: 10.1080/2162402X.2018.1424676. pii: 1424676. pmc: PMC5927527
Publikations ID PMID: 29721389
 


Nintedanib is active in malignant pleural mesothelioma cell models and inhibits angiogenesis and tumor growth in vivo.
Autoren Laszlo V, Valko Z, Kovacs I, Ozsvar J, Hoda MA, Klikovits T, Lakatos D, Czirók A, Garay T, Stiglbauer A, Helbich TH, Groger M, Tovari J, Klepetko W, Pirker C, Grusch M, Berger W, Hilberg F, Hegedus B, Dome B
Erscheinungsdaten Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 May 3. pii: 1078-0432.CCR-17-1507. doi: 10.1158/1078-0432.CCR-17-1507
Publikations ID PMID: 29724868
 


Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins.
Autoren Heilos D, Röhrl C, Pirker C, Englinger B, Baier D, Mohr T, Schwaiger M, Iqbal SM, van Schoonhoven S, Klavins K, Eberhart T, Windberger U, Taibon J, Sturm S, Stuppner H, Koellensperger G, Dornetshuber-Fleiss R, Jäger W, Lemmens-Gruber R, Berger W
Erscheinungsdaten Oncotarget. 2018 May 22. doi: 10.18632/oncotarget.25432. pii: 25432. pmc: PMC5986646
Publikations ID PMID: 29876015
 


TERT promoter mutations are associated with poor prognosis and cell immortalization in meningioma.
Autoren Spiegl-Kreinecker S, Lötsch D, Neumayer K, Kastler L, Gojo J, Pirker C, Pichler J, Weis S, Kumar R, Webersinke G, Gruber A, Berger W
Erscheinungsdaten Neuro-oncology. 2018 Jul 11. pii: 5052146. doi: 10.1093/neuonc/noy104
Publikations ID PMID: 30010853
 


Metal Drugs and the Anticancer Immune Response.
Autoren Englinger B, Pirker C, Heffeter P, Terenzi A, Kowol CR, Keppler BK, Berger W
Erscheinungsdaten Chemical reviews. 2018 Nov 29. doi: 10.1021/acs.chemrev.8b00396
Publikations ID PMID: 30489072
 


Subcellular Duplex DNA and G-Quadruplex Interaction Profiling of a Hexagonal Pt Metallacycle.
Autoren Domarco O, Kieler C, Pirker C, Dinhof C, Englinger B, Reisecker JM, Timelthaler G, García MD, Peinador C, Keppler BK, Berger W, Terenzi A
Erscheinungsdaten Angewandte Chemie (International ed. in English). 2019 Apr 19. doi: 10.1002/anie.201900934
Publikations ID PMID: 31002438
 


TERT expression is susceptible to BRAF and ETS-factor inhibition in BRAF/TERT promoter double-mutated glioma.
Autoren Gabler L, Lötsch D, Kirchhofer D, van Schoonhoven S, Schmidt HM, Mayr L, Pirker C, Neumayer K, Dinhof C, Kastler L, Azizi AA, Dorfer C, Czech T, Haberler C, Peyrl A, Kumar R, Slavc I, Spiegl-Kreinecker S, Gojo J, Berger W
Erscheinungsdaten Acta neuropathologica communications. 2019 Aug 7. doi: 10.1186/s40478-019-0775-6. pii: 10.1186/s40478-019-0775-6
Publikations ID PMID: 31391125
 


Expression of FGFR1-4 in Malignant Pleural Mesothelioma Tissue and Corresponding Cell Lines and its Relationship to Patient Survival and FGFR Inhibitor Sensitivity.
Autoren Vlacic G, Hoda MA, Klikovits T, Sinn K, Gschwandtner E, Mohorcic K, Schelch K, Pirker C, Peter-Vörösmarty B, Brankovic J, Dome B, Laszlo V, Cufer T, Rozman A, Klepetko W, Grasl-Kraupp B, Hegedus B, Berger W, Kern I, Grusch M
Erscheinungsdaten Cells. 2019 Sep 16. pii: cells8091091. doi: 10.3390/cells8091091
Publikations ID PMID: 31527449
 


Combined MEK and PI3K/p110b inhibition as a novel targeted therapy for malignant mesothelioma displaying sarcomatoid features.
Autoren Marqués M, Tranchant R, Risa-Ebrí B, Suárez-Solís ML, Fernández LC, Carrillo-de-Santa-Pau E, Del Pozo N, Martínez de Villarreal J, Meiller C, Allory Y, Blum Y, Pirker C, Hegedus B, Barry ST, Carnero A, Berger W, Jean D, Real FX
Erscheinungsdaten Cancer research. 2020 Jan 7. pii: 0008-5472.CAN-19-1633. doi: 10.1158/0008-5472.CAN-19-1633
Publikations ID PMID: 31911549
 


Lipid Droplet-Mediated Scavenging As Novel Intrinsic And Adaptive Resistance Factor Against The Multikinase Inhibitor Ponatinib.
Autoren Englinger B, Laemmerer A, Moser P, Kallus S, Röhrl C, Pirker C, Baier D, Mohr T, Niederstaetter L, Meier-Menches SM, Gerner C, Gabler L, Gojo J, Timelthaler G, Senkiv J, Jäger W, Kowol CR, Heffeter P, Berger W
Erscheinungsdaten International journal of cancer. 2020 Feb 16. doi: 10.1002/ijc.32924
Publikations ID PMID: 32064608
 


Comparative analysis of prognostic histopathologic parameters in subtypes of epithelioid pleural mesothelioma.
Autoren Bilecz A, Stockhammer P, Theegarten D, Kern I, Jakopovic M, Samarzija M, Klikovits T, Hoda MA, Döme B, Oberndorfer F, Muellauer L, Fillinger J, Kovács I, Pirker C, Schuler M, Plönes T, Aigner C, Klepetko W, Berger W, Brcic L, Laszlo V, Hegedus B
Erscheinungsdaten Histopathology. 2020 Mar 14. doi: 10.1111/his.14105
Publikations ID PMID: 32170970
 


I Radiolabeling of a Au -NHC Complex for In Vivo Biodistribution Studies.
Autoren Guarra F, Terenzi A, Pirker C, Passannante R, Baier D, Zangrando E, Gómez-Vallejo V, Biver T, Gabbiani C, Berger W, Llop J, Salassa L
Erscheinungsdaten Angewandte Chemie (International ed. in English). 2020 Jul 7. doi: 10.1002/anie.202008046
Publikations ID PMID: 32633820
 


Homeopathic Treatment as an 'Add on' Therapy May Improve Quality of Life and Prolong Survival in Patients with Non-Small Cell Lung Cancer: A Prospective, Randomized, Placebo-Controlled, Double-Blind, Three-Arm, Multicenter Study.
Autoren Frass M, Lechleitner P, Gründling C, Pirker C, Grasmuk-Siegl E, Domayer J, Hochmayr M, Gaertner K, Duscheck C, Muchitsch I, Marosi C, Schumacher M, Zöchbauer-Müller S, Manchanda RK, Schrott A, Burghuber O
Erscheinungsdaten The oncologist. 2020 Oct 3. doi: 10.1002/onco.13548
Publikations ID PMID: 33010094
 


p53 Loss Mediates Hypersensitivity to ETS Transcription Factor Inhibition Based on PARylation-Mediated Cell Death Induction.
Autoren Dinhof C, Pirker C, Kroiss P, Kirchhofer D, Gabler L, Gojo J, Lötsch-Gojo D, Stojanovic M, Timelthaler G, Ferk F, Knasmüller S, Reisecker J, Spiegl-Kreinecker S, Birner P, Preusser M, Berger W
Erscheinungsdaten Cancers. 2020 Oct 30. pii: cancers12113205. doi: 10.3390/cancers12113205
Publikations ID PMID: 33143299
 


Targeting fibroblast growth factor receptors to combat aggressive ependymoma.
Autoren Lötsch D, Kirchhofer D, Englinger B, Jiang L, Okonechnikov K, Senfter D, Laemmerer A, Gabler L, Pirker C, Donson AM, Bannauer P, Korbel P, Jaunecker CN, Hübner JM, Mayr L, Madlener S, Schmook MT, Ricken G, Maaß K, Grusch M, Holzmann K, Grasl-Kraupp B, Spiegl-Kreinecker S, Hsu J, Dorfer C, Rössler K, Azizi AA, Foreman NK, Peyrl A, Haberler C, Czech T, Slavc I, Filbin MG, Pajtler KW, Kool M, Berger W, Gojo J
Erscheinungsdaten Acta neuropathologica. 2021 May 27. doi: 10.1007/s00401-021-02327-x. pii: 10.1007/s00401-021-02327-x
Publikations ID PMID: 34046693
 


Discrimination between 34 of 36 Possible Combinations of Three C>T SNP Genotypes in the Promoter by High Resolution Melting Analysis Coupled with Pyrosequencing Using A Single Primer Set.
Autoren Zappe K, Pirker C, Miedl H, Schreiber M, Heffeter P, Pfeiler G, Hacker S, Haslik W, Spiegl-Kreinecker S, Cichna-Markl M
Erscheinungsdaten International journal of molecular sciences. 2021 Nov 20. pii: ijms222212527. doi: 10.3390/ijms222212527
Publikations ID PMID: 34830407
 


The Anticancer Ruthenium Compound BOLD-100 Targets Glycolysis and Generates a Metabolic Vulnerability towards Glucose Deprivation.
Autoren Baier D, Schoenhacker-Alte B, Rusz M, Pirker C, Mohr T, Mendrina T, Kirchhofer D, Meier-Menches SM, Hohenwallner K, Schaier M, Rampler E, Koellensperger G, Heffeter P, Keppler B, Berger W
Erscheinungsdaten Pharmaceutics. 2022 Jan 20. pii: pharmaceutics14020238. doi: 10.3390/pharmaceutics14020238
Publikations ID PMID: 35213972
 


Fibroblast growth factor receptor 4 promotes glioblastoma progression: a central role of integrin-mediated cell invasiveness.
Autoren Gabler L, Jaunecker CN, Katz S, van Schoonhoven S, Englinger B, Pirker C, Mohr T, Vician P, Stojanovic M, Woitzuck V, Laemmerer A, Kirchhofer D, Mayr L, LaFranca M, Erhart F, Grissenberger S, Wenninger-Weinzierl A, Sturtzel C, Kiesel B, Lang A, Marian B, Grasl-Kraupp B, Distel M, Schüler J, Gojo J, Grusch M, Spiegl-Kreinecker S, Donoghue DJ, Lötsch D, Berger W
Erscheinungsdaten Acta neuropathologica communications. 2022 Apr 28. doi: 10.1186/s40478-022-01363-2. pii: 10.1186/s40478-022-01363-2
Publikations ID PMID: 35484633
 


Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T-cell lymphoma.
Autoren Sorger H, Dey S, Vieyra-Garcia PA, Pölöske D, Teufelberger AR, de Araujo ED, Sedighi A, Graf R, Spiegl B, Lazzeri I, Braun T, Garces de Los Fayos Alonso I, Schlederer M, Timelthaler G, Kodajova P, Pirker C, Surbek M, Machtinger M, Graier T, Perchthaler I, Pan Y, Fink-Puches R, Cerroni L, Ober J, Otte M, Albrecht JD, Tin G, Abdeldayem A, Manaswiyoungkul P, Olaoye OO, Metzelder ML, Orlova A, Berger W, Wobser M, Nicolay JP, André F, Nguyen VA, Neubauer HA, Fleck R, Merkel O, Herling M, Heitzer E, Gunning PT, Kenner L, Moriggl R, Wolf P
Erscheinungsdaten EMBO molecular medicine. 2022 Nov 7. doi: 10.15252/emmm.202115200
Publikations ID PMID: 36341492
 


Trabectedin Is Active against Two Novel, Patient-Derived Solitary Fibrous Pleural Tumor Cell Lines and Synergizes with Ponatinib.
Autoren Ghanim B, Baier D, Pirker C, Müllauer L, Sinn K, Lang G, Hoetzenecker K, Berger W
Erscheinungsdaten Cancers. 2022 Nov 15. doi: 10.3390/cancers14225602. pii: cancers14225602
Publikations ID PMID: 36428694
 


Mesothelioma-associated fibroblasts enhance proliferation and migration of pleural mesothelioma cells via c-Met/PI3K and WNT signaling but do not protect against cisplatin.
Autoren Ries A, Flehberger D, Slany A, Pirker C, Mader JC, Mohr T, Schelch K, Sinn K, Mosleh B, Hoda MA, Dome B, Dolznig H, Krupitza G, Müllauer L, Gerner C, Berger W, Grusch M
Erscheinungsdaten Journal of experimental & clinical cancer research : CR. 2023 Jan 23. doi: 10.1186/s13046-022-02582-0. pii: 10.1186/s13046-022-02582-0
Publikations ID PMID: 36683050
 


A platinum(IV) prodrug strategy to overcome glutathione-based oxaliplatin resistance.
Autoren Fronik P, Gutmann M, Vician P, Stojanovic M, Kastner A, Heffeter P, Pirker C, Keppler BK, Berger W, Kowol CR
Erscheinungsdaten Communications chemistry. 2022 Apr 6. doi: 10.1038/s42004-022-00661-z. pii: 10.1038/s42004-022-00661-z. pmc: PMC9814792
Publikations ID PMID: 36697790
 


Landomycins as glutathione-depleting agents and natural fluorescent probes for cellular Michael adduct-dependent quinone metabolism.
Autoren Terenzi A, La Franca M, van Schoonhoven S, Panchuk R, Martínez Á, Heffeter P, Gober R, Pirker C, Vician P, Kowol CR, Stoika R, Salassa L, Rohr J, Berger W
Erscheinungsdaten Communications chemistry. 2021 Nov 25. doi: 10.1038/s42004-021-00600-4. pii: 10.1038/s42004-021-00600-4. pmc: PMC9814637
Publikations ID PMID: 36697631
 


Influence of the Fatty Acid Metabolism on the Mode of Action of a Cisplatin(IV) Complex with Phenylbutyrate as Axial Ligands.
Autoren Mendrina T, Poetsch I, Schueffl H, Baier D, Pirker C, Ries A, Keppler BK, Kowol CR, Gibson D, Grusch M, Berger W, Heffeter P
Erscheinungsdaten Pharmaceutics. 2023 Feb 16. doi: 10.3390/pharmaceutics15020677. pii: pharmaceutics15020677
Publikations ID PMID: 36839999
 


A novel EGFR inhibitor acts as potent tool for hypoxia-activated prodrug systems and exerts strong synergistic activity with VEGFR inhibition in vitro and in vivo.
Autoren Caban M, Koblmueller B, Groza D, Schueffl HH, Terenzi A, Tolios A, Mohr T, Mathuber M, Kryeziu K, Jaunecker C, Pirker C, Keppler BK, Berger W, Kowol CR, Heffeter P
Erscheinungsdaten Cancer letters. 2023 May 19. doi: 10.1016/j.canlet.2023.216237. pii: S0304-3835(23)00188-X
Publikations ID PMID: 37211067
 


Aberrant DNA Methylation, Expression, and Occurrence of Transcript Variants of the ABC Transporter in Breast Cancer.
Autoren Zappe K, Kopic A, Scheichel A, Schier AK, Schmidt LE, Borutzki Y, Miedl H, Schreiber M, Mendrina T, Pirker C, Pfeiler G, Hacker S, Haslik W, Pils D, Bileck A, Gerner C, Meier-Menches S, Heffeter P, Cichna-Markl M
Erscheinungsdaten Cells. 2023 May 24. doi: 10.3390/cells12111462. pii: cells12111462
Publikations ID PMID: 37296582
 


Primary and hTERT-Transduced Mesothelioma-Associated Fibroblasts but Not Primary or hTERT-Transduced Mesothelial Cells Stimulate Growth of Human Mesothelioma Cells.
Autoren Ries A, Slany A, Pirker C, Mader JC, Mejri D, Mohr T, Schelch K, Flehberger D, Maach N, Hashim M, Hoda MA, Dome B, Krupitza G, Berger W, Gerner C, Holzmann K, Grusch M
Erscheinungsdaten Cells. 2023 Aug 5. doi: 10.3390/cells12152006. pii: cells12152006
Publikations ID PMID: 37566084
 


Krebs von den Lungen 6 (KL-6) is a novel diagnostic and prognostic biomarker in pleural mesothelioma.
Autoren Stockhammer P, Baumeister H, Ploenes T, Bonella F, Theegarten D, Dome B, Pirker C, Berger W, Hegedüs L, Baranyi M, Schuler M, Deshayes S, Bölükbas S, Aigner C, Blanquart C, Hegedüs B
Erscheinungsdaten Lung cancer (Amsterdam, Netherlands). 2023 Sep 7. doi: 10.1016/j.lungcan.2023.107360. pii: S0169-5002(23)00898-X
Publikations ID PMID: 37713954
 


Epidermal Growth Factor Receptor Mutation-Positive Non-Small-Cell Lung Cancer in the Real-World Setting in Central Europe: The INSIGHT Study.
Autoren Ramlau R, Cufer T, Berzinec P, Dziadziuszko R, Olszewski W, Popper H, Bajcic P, Dušek L, Zbozinkova Z, Pirker R
Erscheinungsdaten Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2015 Aug 21. doi: 10.1097/JTO.0000000000000621. pii: 01243894-201509000-00019
Publikations ID PMID: 26291014
 


Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo-controlled trial.
Autoren Gnant M, Pfeiler G, Dubsky PC, Hubalek M, Greil R, Jakesz R, Wette V, Balic M, Haslbauer F, Melbinger E, Bjelic-Radisic V, Artner-Matuschek S, Fitzal F, Marth C, Sevelda P, Mlineritsch B, Steger GG, Manfreda D, Exner R, Egle D, Bergh J, Kainberger F, Talbot S, Warner D, Fesl C, Singer CF
Erscheinungsdaten Lancet (London, England). 2015 May 31. pii: S0140-6736(15)60995-3. doi: 10.1016/S0140-6736(15)60995-3
Publikations ID PMID: 26040499
 


Adjuvant chemotherapy in patients with completely resected non-small cell lung cancer.
Autoren Pirker R
Erscheinungsdaten Translational lung cancer research. 2015 Mar 25. doi: 10.3978/j.issn.2218-6751.2014.09.13. pii: tlcr-03-05-305. pmc: PMC4367797
Publikations ID PMID: 25806316
 


Epidermal growth factor receptor-directed monoclonal antibodies in nonsmall cell lung cancer: an update.
Autoren Pirker R
Erscheinungsdaten Current opinion in oncology. 2015 Feb 4. doi: 10.1097/CCO.0000000000000162
Publikations ID PMID: 25636162
 


Perspectives of novel imaging techniques for staging, therapy response assessment, and monitoring of surveillance in lung cancer: summary of the Dresden 2013 Post WCLC-IASLC State-of-the-Art Imaging Workshop.
Autoren Henzler T, Goldstraw P, Wenz F, Pirker R, Weder W, Apfaltrer P, Meyer M, Buesing K, Crino L, Fennell D, Fink C, Grunenwald D, Manegold C, Pilz L, Schoenberg SO, Suresh S, Vansteenkiste J, Voigt W, Wängler B, Schmid-Bindert G
Erscheinungsdaten Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2015 Jan 23. doi: 10.1097/JTO.0000000000000412. pii: 01243894-201502000-00004
Publikations ID PMID: 25611226
 


Relationship between EGFR expression, EGFR mutation status, and the efficacy of chemotherapy plus cetuximab in FLEX study patients with advanced non-small-cell lung cancer.
Autoren Douillard JY, Pirker R, O'Byrne KJ, Kerr KM, Störkel S, von Heydebreck A, Grote HJ, Celik I, Shepherd FA
Erscheinungsdaten Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2014 Apr 11. doi: 10.1097/JTO.0000000000000141
Publikations ID PMID: 24662454
 


Mechanism of reaction of chlorite with mammalian heme peroxidases.
Autoren Jakopitsch C, Pirker KF, Flemmig J, Hofbauer S, Schlorke D, Furtmüller PG, Arnhold J, Obinger C
Erscheinungsdaten Journal of inorganic biochemistry. 2014 Feb 28. pii: S0162-0134(14)00061-0. doi: 10.1016/j.jinorgbio.2014.02.010. pmc: PMC4003552
Publikations ID PMID: 24632343
 


Significance of TP53 mutations as predictive markers of adjuvant cisplatin-based chemotherapy in completely resected non-small-cell lung cancer.
Autoren Ma X, Rousseau V, Sun H, Lantuejoul S, Filipits M, Pirker R, Popper H, Mendiboure J, Vataire AL, Le Chevalier T, Soria JC, Brambilla E, Dunant A, Hainaut P
Erscheinungsdaten Molecular oncology. 2014 Jan 15. pii: S1574-7891(13)00187-7. doi: 10.1016/j.molonc.2013.12.015
Publikations ID PMID: 24495481
 


Three Metachronous Osteosarcomas within 22 Years without Pulmonary Metastases: A Case Report and Review of the Literature.
Autoren Pirker-Frühauf UM, Friesenbichler J, Rabitsch K, Liegl-Atzwanger B, Bauernhofer T, Windhager R, Leithner A
Erscheinungsdaten Case reports in orthopedics. 2013 Dec 25. doi: 10.1155/2013/197287. pmc: PMC3886224
Publikations ID PMID: 24455368
 


Overcoming resistance to first generation EGFR TKIs with cetuximab in combination with chemotherapy in an EGFR mutated advanced stage NSCLC patient.
Autoren Pircher A, Manzl C, Fiegl M, Popper H, Pirker R, Hilbe W
Erscheinungsdaten Lung cancer (Amsterdam, Netherlands). 2013 Dec 25. pii: S0169-5002(13)00572-2. doi: 10.1016/j.lungcan.2013.12.007
Publikations ID PMID: 24412619
 


Novel drugs against non-small-cell lung cancer.
Autoren Pirker R
Erscheinungsdaten Current opinion in oncology. 2014 Feb 7. doi: 10.1097/CCO.0000000000000056
Publikations ID PMID: 24406751
 


Meta-analysis of individual patient data from randomized trials of chemotherapy plus cetuximab as first-line treatment for advanced non-small cell lung cancer.
Autoren Pujol JL, Pirker R, Lynch TJ, Butts CA, Rosell R, Shepherd FA, Vansteenkiste J, O'Byrne KJ, de Blas B, Heighway J, von Heydebreck A, Thatcher N
Erscheinungsdaten Lung cancer (Amsterdam, Netherlands). 2013 Nov 16. pii: S0169-5002(13)00517-5. doi: 10.1016/j.lungcan.2013.11.006
Publikations ID PMID: 24332319
 


EGFR-directed monoclonal antibodies in non-small cell lung cancer.
Autoren Pirker R
Erscheinungsdaten Targeted oncology. 2013 Jan 9. doi: 10.1007/s11523-012-0244-7
Publikations ID PMID: 23300028
 


EGFR-directed monoclonal antibodies in non-small cell lung cancer: how to predict efficacy?
Autoren Pirker R
Erscheinungsdaten Translational lung cancer research. 2015 Mar 25. doi: 10.3978/j.issn.2218-6751.2012.10.09. pii: tlcr-01-04-269. pmc: PMC4367547
Publikations ID PMID: 25806192
 


Hemoglobin decline in cancer patients receiving chemotherapy without an erythropoiesis-stimulating agent.
Autoren Pirker R, Pirolli M, Quigley J, Hulnick S, Legg J, Collins H, Vansteenkiste J
Erscheinungsdaten Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 2012 Oct 25. doi: 10.1007/s00520-012-1617-2. pmc: PMC3584249
Publikations ID PMID: 23096072
 


Prognostic factors in patients with advanced non-small cell lung cancer: data from the phase III FLEX study.
Autoren Pirker R, Pereira JR, Szczesna A, von Pawel J, Krzakowski M, Ramlau R, Vynnychenko I, Park K, Eberhardt WE, de Marinis F, Heeger S, Goddemeier T, O'Byrne KJ, Gatzemeier U
Erscheinungsdaten Lung cancer (Amsterdam, Netherlands). 2012 Apr 11. pii: S0169-5002(12)00121-3. doi: 10.1016/j.lungcan.2012.03.010
Publikations ID PMID: 22498112
 


Cetuximab in non-small-cell lung cancer.
Autoren Pirker R, Filipits M
Erscheinungsdaten Translational lung cancer research. 2015 Mar 25. doi: 10.3978/j.issn.2218-6751.11.01. pii: tlcr-01-01-054. pmc: PMC4367590
Publikations ID PMID: 25806155
 


Adjuvant chemotherapy of non-small cell lung cancer.
Autoren Pirker R
Erscheinungsdaten Tanaffos. 2014 Sep 5. pmc: PMC4153177
Publikations ID PMID: 25191395
 


EGFR expression as a predictor of survival for first-line chemotherapy plus cetuximab in patients with advanced non-small-cell lung cancer: analysis of data from the phase 3 FLEX study.
Autoren Pirker R, Pereira JR, von Pawel J, Krzakowski M, Ramlau R, Park K, de Marinis F, Eberhardt WE, Paz-Ares L, Störkel S, Schumacher KM, von Heydebreck A, Celik I, O'Byrne KJ
Erscheinungsdaten The Lancet. Oncology. 2011 Nov 4. pii: S1470-2045(11)70318-7. doi: 10.1016/S1470-2045(11)70318-7
Publikations ID PMID: 22056021
 


Chemotherapy: advanced NSCLC--should we use doublets in elderly patients?
Autoren Pirker R
Erscheinungsdaten Nature reviews. Clinical oncology. 2011 Sep 27. pii: nrclinonc.2011.147. doi: 10.1038/nrclinonc.2011.147
Publikations ID PMID: 21946845
 


Third CECOG consensus on the systemic treatment of non-small-cell lung cancer.
Autoren Brodowicz T, Ciuleanu T, Crawford J, Filipits M, Fischer JR, Georgoulias V, Gridelli C, Hirsch FR, Jassem J, Kosmidis P, Krzakowski M, Manegold Ch, Pujol JL, Stahel R, Thatcher N, Vansteenkiste J, Minichsdorfer C, Zöchbauer-Müller S, Pirker R, Zielinski CC
Erscheinungsdaten Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 2011 Sep 22. pii: mdr381. doi: 10.1093/annonc/mdr381
Publikations ID PMID: 21940784
 


Predictive markers in the adjuvant therapy of non-small cell lung cancer.
Autoren Filipits M, Pirker R
Erscheinungsdaten Lung cancer (Amsterdam, Netherlands). 2011 Aug 31. pii: S0169-5002(11)00335-7. doi: 10.1016/j.lungcan.2011.06.005
Publikations ID PMID: 21885151
 


Monoclonal antibodies against EGFR in non-small cell lung cancer.
Autoren Pirker R, Filipits M
Erscheinungsdaten Critical reviews in oncology/hematology. 2010 Nov 24. pii: S1040-8428(10)00244-1. doi: 10.1016/j.critrevonc.2010.10.008
Publikations ID PMID: 21109448
 


Consensus for EGFR mutation testing in non-small cell lung cancer: results from a European workshop.
Autoren Pirker R, Herth FJ, Kerr KM, Filipits M, Taron M, Gandara D, Hirsch FR, Grunenwald D, Popper H, Smit E, Dietel M, Marchetti A, Manegold C, Schirmacher P, Thomas M, Rosell R, Cappuzzo F, Stahel R
Erscheinungsdaten Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2010 Sep 27. doi: 10.1097/JTO.0b013e3181f1c8de. pii: 01243894-201010000-00033
Publikations ID PMID: 20871269
 


Therapy of small cell lung cancer with emphasis on oral topotecan.
Autoren Pirker R, Berzinec P, Brincat S, Kasan P, Ostoros G, Pesek M, Plāte S, Purkalne G, Rooneem R, Skricková J, Stanculeanu D, Timcheva C, Tzekova V, Zakotnik B, Zielinski CC, Zwitter M
Erscheinungsdaten Lung cancer (Amsterdam, Netherlands). 2010 Jun 23. pii: S0169-5002(10)00266-7. doi: 10.1016/j.lungcan.2010.05.020
Publikations ID PMID: 20576312
 


Chemotherapy of advanced non-small cell lung cancer.
Autoren Pirker R, Minar W
Erscheinungsdaten Frontiers of radiation therapy and oncology. 2009 Nov 24. pii: 000262471. doi: 10.1159/000262471
Publikations ID PMID: 19955802
 


Erythropoiesis-stimulating agents in patients with cancer: update on safety issues.
Autoren Pirker R
Erscheinungsdaten Expert opinion on drug safety. 2009 Aug 25. doi: 10.1517/14740330903158929
Publikations ID PMID: 19637988
 


Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial.
Autoren Pirker R, Pereira JR, Szczesna A, von Pawel J, Krzakowski M, Ramlau R, Vynnychenko I, Park K, Yu CT, Ganul V, Roh JK, Bajetta E, O'Byrne K, de Marinis F, Eberhardt W, Goddemeier T, Emig M, Gatzemeier U
Erscheinungsdaten Lancet (London, England). 2009 May 4. pii: S0140-6736(09)60569-9. doi: 10.1016/S0140-6736(09)60569-9
Publikations ID PMID: 19410716
 


Targeted therapies in lung cancer.
Autoren Pirker R, Filipits M
Erscheinungsdaten Current pharmaceutical design. 2009 Jan 19.
Publikations ID PMID: 19149612
 


Cetuximab: potential role as first-line treatment for advanced non-small cell lung cancer.
Autoren Pirker R
Erscheinungsdaten Clinical advances in hematology & oncology : H&O. 2008 Nov 10.
Publikations ID PMID: 18997663
 


Safety and efficacy of darbepoetin alpha in previously untreated extensive-stage small-cell lung cancer treated with platinum plus etoposide.
Autoren Pirker R, Ramlau RA, Schuette W, Zatloukal P, Ferreira I, Lillie T, Vansteenkiste JF
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2008 May 9. pii: 26/14/2342. doi: 10.1200/JCO.2007.15.0748
Publikations ID PMID: 18467726
 


Integrating epidermal growth factor receptor-targeted therapies into platinum-based chemotherapy regimens for newly diagnosed non-small-cell lung cancer.
Autoren Pirker R, Minar W, Filipits M
Erscheinungsdaten Clinical lung cancer. 2009 May 7. pii: 8283T3NM41K23842. doi: 10.3816/CLC.2008.s.016
Publikations ID PMID: 19419924
 


Activated mammalian target of rapamycin is an adverse prognostic factor in patients with biliary tract adenocarcinoma.
Autoren Herberger B, Puhalla H, Lehnert M, Wrba F, Novak S, Brandstetter A, Gruenberger B, Gruenberger T, Pirker R, Filipits M
Erscheinungsdaten Clinical cancer research : an official journal of the American Association for Cancer Research. 2007 Aug 16. pii: 13/16/4795. doi: 10.1158/1078-0432.CCR-07-0738
Publikations ID PMID: 17699857
 


Multidrug resistance proteins do not predict benefit of adjuvant chemotherapy in patients with completely resected non-small cell lung cancer: International Adjuvant Lung Cancer Trial Biologic Program.
Autoren Filipits M, Haddad V, Schmid K, Huynh A, Dunant A, André F, Brambilla E, Stahel R, Pignon JP, Soria JC, Popper HH, Le Chevalier T, Pirker R
Erscheinungsdaten Clinical cancer research : an official journal of the American Association for Cancer Research. 2007 Jul 3. pii: 13/13/3892. doi: 10.1158/1078-0432.CCR-06-2446
Publikations ID PMID: 17606722
 


Cell cycle regulators and outcome of adjuvant cisplatin-based chemotherapy in completely resected non-small-cell lung cancer: the International Adjuvant Lung Cancer Trial Biologic Program.
Autoren Filipits M, Pirker R, Dunant A, Lantuejoul S, Schmid K, Huynh A, Haddad V, André F, Stahel R, Pignon JP, Soria JC, Popper HH, Le Chevalier T, Brambilla E
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2007 Jul 2. pii: 25/19/2735. doi: 10.1200/JCO.2006.08.2867
Publikations ID PMID: 17602078
 


Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer.
Autoren Heller G, Geradts J, Ziegler B, Newsham I, Filipits M, Markis-Ritzinger EM, Kandioler D, Berger W, Stiglbauer W, Depisch D, Pirker R, Zielinski CC, Zöchbauer-Müller S
Erscheinungsdaten Breast cancer research and treatment. 2007 Jan 27. doi: 10.1007/s10549-006-9377-7
Publikations ID PMID: 17260099
 


Achieving full-dose, on-schedule administration of ACE chemotherapy every 14 days for the treatment of patients with extensive small-cell lung cancer.
Autoren Pirker R, Ulsperger E, Messner J, Aigner K, Forstner B, Bacon P, Easton V, Skacel T
Erscheinungsdaten Lung. 2007 Jan 19. doi: 10.1007/s00408-005-2594-8
Publikations ID PMID: 17235728
 


Safety considerations for erythropoietin treatment in patients with cancer.
Autoren Pirker R
Erscheinungsdaten Expert opinion on drug safety. 2006 Dec 21. doi: 10.1517/14740338.6.1.63
Publikations ID PMID: 17181453
 


Once-weekly epoetin beta (30,000 IU) in anemic patients with lung cancer receiving chemotherapy.
Autoren Pirker R, Lehnert M, Minar W
Erscheinungsdaten Lung cancer (Amsterdam, Netherlands). 2006 Nov 3. pii: S0169-5002(06)00529-0. doi: 10.1016/j.lungcan.2006.09.020
Publikations ID PMID: 17084484
 


Induction chemotherapy with the TIP regimen (paclitaxel/ifosfamide/cisplatin) in stage III non-small cell lung cancer.
Autoren Pohl G, Krajnik G, Malayeri R, Müller RM, Klepetko W, Eckersberger F, Schäfer-Prokop C, Pokrajac B, Schmeikal S, Maier A, Ambrosch G, Woltsche M, Minar W, Pirker R
Erscheinungsdaten Lung cancer (Amsterdam, Netherlands). 2006 Aug 22. pii: S0169-5002(06)00313-8. doi: 10.1016/j.lungcan.2006.05.027
Publikations ID PMID: 16926060
 


Application and safety of erythropoietin in cancer management.
Autoren Pirker R, Minar W
Erscheinungsdaten Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 2005 Jun 16. pii: 16/suppl_2/ii47. doi: 10.1093/annonc/mdi716
Publikations ID PMID: 15958474
 


Clinical role of multidrug resistance protein 1 expression in chemotherapy resistance in early-stage breast cancer: the Austrian Breast and Colorectal Cancer Study Group.
Autoren Filipits M, Pohl G, Rudas M, Dietze O, Lax S, Grill R, Pirker R, Zielinski CC, Hausmaninger H, Kubista E, Samonigg H, Jakesz R
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2005 Feb 18. pii: 23/6/1161. doi: 10.1200/JCO.2005.03.033
Publikations ID PMID: 15718312
 


Therapy of advanced non-small-cell lung cancer (take home message).
Autoren Pirker R
Erscheinungsdaten Lung cancer (Amsterdam, Netherlands). 2004 Nov 19. pii: S0169-5002(04)80034-5. doi: 10.1016/j.lungcan.2004.07.966
Publikations ID PMID: 15552808
 


Darbepoetin alfa for the treatment of cancer-related anemia: an update.
Autoren Pirker R
Erscheinungsdaten Expert review of anticancer therapy. 2004 Oct 15. pii: ERA040505. doi: 10.1586/14737140.4.5.735
Publikations ID PMID: 15485310
 


Two- versus three-drug combinations in the chemotherapy of advanced non-small-cell lung cancer.
Autoren Pirker R
Erscheinungsdaten Lung cancer (Amsterdam, Netherlands). 2002 Dec 6. pii: S0169500202002702
Publikations ID PMID: 12468147
 


New drugs in the palliative chemotherapy of advanced non-small-cell lung cancer.
Autoren Malayeri R, Pirker R, Huber H
Erscheinungsdaten Onkologie. 2001 Nov 5. pii: 55121. doi: 55121
Publikations ID PMID: 11694767
 


P-glycoprotein and MRP1 expression in axillary lymph node metastases of breast cancer patients.
Autoren Zöchbauer-Müller S, Filipits M, Rudas M, Brunner R, Krajnik G, Suchomel R, Schmid K, Pirker R
Erscheinungsdaten Anticancer research. 2001 Apr 12.
Publikations ID PMID: 11299725
 


Drug resistance factors in acute myeloid leukemia: a comparative analysis.
Autoren Filipits M, Stranzl T, Pohl G, Heinzl H, Jäger U, Geissler K, Fonatsch C, Haas OA, Lechner K, Pirker R
Erscheinungsdaten Leukemia. 2000 Feb 2.
Publikations ID PMID: 10637479
 


MRP expression in acute myeloid leukemia. An update.
Autoren Filipits M, Stranzl T, Pohl G, Suchomel RW, Zöchbauer S, Brunner R, Lechner K, Pirker R
Erscheinungsdaten Advances in experimental medicine and biology. 1999 Nov 4.
Publikations ID PMID: 10500789
 


The lung resistance protein (LRP) predicts poor outcome in acute myeloid leukemia.
Autoren Pirker R, Pohl G, Stranzl T, Suchomel RW, Scheper RJ, Jäger U, Geissler K, Lechner K, Filipits M
Erscheinungsdaten Advances in experimental medicine and biology. 1999 Nov 4.
Publikations ID PMID: 10500788
 


The TP53 genotype but not immunohistochemical result is predictive of response to cisplatin-based neoadjuvant therapy in stage III non-small cell lung cancer.
Autoren Kandioler-Eckersberger D, Kappel S, Mittlböck M, Dekan G, Ludwig C, Janschek E, Pirker R, Wolner E, Eckersberger F
Erscheinungsdaten The Journal of thoracic and cardiovascular surgery. 1999 Apr 16. pii: S002252239900149X
Publikations ID PMID: 10096970
 


Vinorelbine/gemcitabine in advanced non-small cell lung cancer (NSCLC): a phase I trial.
Autoren Krajnik G, Wein W, Greil R, Marhold F, Mohn-Staudner A, Kummer F, Malayeri R, Zöchbauer-Müller S, Huber H, Pirker R
Erscheinungsdaten European journal of cancer (Oxford, England : 1990). 1999 Feb 25. pii: S0959-8049(98)00235-4
Publikations ID PMID: 10023326
 


Expression of the lung resistance protein predicts poor outcome in de novo acute myeloid leukemia.
Autoren Filipits M, Pohl G, Stranzl T, Suchomel RW, Scheper RJ, Jäger U, Geissler K, Lechner K, Pirker R
Erscheinungsdaten Blood. 1998 Mar 16.
Publikations ID PMID: 9473213
 


Multidrug resistance-associated protein in acute myeloid leukemia: No impact on treatment outcome.
Autoren Filipits M, Suchomel RW, Zöchbauer S, Brunner R, Lechner K, Pirker R
Erscheinungsdaten Clinical cancer research : an official journal of the American Association for Cancer Research. 1999 Feb 25.
Publikations ID PMID: 9815827
 


MDR1 RNA transcripts do not indicate long-term prognosis in colorectal carcinomas.
Autoren Zöchbauer S, Wallner J, Haider K, Depisch D, Huber H, Pirker R
Erscheinungsdaten European journal of cancer (Oxford, England : 1990). 1997 Nov 3. pii: S0959804997001391
Publikations ID PMID: 9337699
 


Neurological monitoring of neurotoxicity induced by paclitaxel/cisplatin chemotherapy.
Autoren Berger T, Malayeri R, Doppelbauer A, Krajnik G, Huber H, Auff E, Pirker R
Erscheinungsdaten European journal of cancer (Oxford, England : 1990). 1997 Nov 3. pii: S0959804997001032
Publikations ID PMID: 9337680
 


Immunocytochemical detection of the multidrug resistance-associated protein and P-glycoprotein in acute myeloid leukemia: impact of antibodies, sample source and disease status.
Autoren Filipits M, Suchomel RW, Lechner K, Pirker R
Erscheinungsdaten Leukemia. 1997 Jul 17.
Publikations ID PMID: 9204994
 


Expression of the multidrug resistance-associated protein (MRP) gene in colorectal carcinomas.
Autoren Fillpits M, Suchomel RW, Dekan G, Stiglbauer W, Haider K, Depisch D, Pirker R
Erscheinungsdaten British journal of cancer. 1997 Feb 20. pmc: PMC2063277
Publikations ID PMID: 9010028
 


Multidrug resistance in leukemias and its reversal.
Autoren Malayeri R, Filipits M, Suchomel RW, Zöchbauer S, Lechner K, Pirker R
Erscheinungsdaten Leukemia & lymphoma. 1997 Apr 11. doi: 10.3109/10428199609054853
Publikations ID PMID: 9031075
 


MRP and MDR1 gene expression in primary breast carcinomas.
Autoren Filipits M, Suchomel RW, Dekan G, Haider K, Valdimarsson G, Depisch D, Pirker R
Erscheinungsdaten Clinical cancer research : an official journal of the American Association for Cancer Research. 1999 Feb 9.
Publikations ID PMID: 9816292
 


Clinical relevance of drug resistance genes in malignant disease.
Autoren Filipits M, Suchomel RW, Zöchbauer S, Malayeri R, Pirker R
Erscheinungsdaten Leukemia. 1996 Jul 26.
Publikations ID PMID: 8656694
 


Paclitaxel/cisplatin in advanced non-small-cell lung cancer (NSCLC).
Autoren Pirker R, Krajnik G, Zöchbauer S, Malayeri R, Kneussl M, Huber H
Erscheinungsdaten Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 1996 Mar 27.
Publikations ID PMID: 8589023
 


P-glycoprotein expression as unfavorable prognostic factor in acute myeloid leukemia.
Autoren Zöchbauer S, Gsur A, Brunner R, Kyrle PA, Lechner K, Pirker R
Erscheinungsdaten Leukemia. 1994 Jul 13.
Publikations ID PMID: 7516030
 


MDR1 gene expression in chronic lymphocytic leukemia.
Autoren Wallner J, Gisslinger H, Gisslinger B, Gsur A, Götzl M, Zöchbauer S, Pirker R
Erscheinungsdaten Leukemia & lymphoma. 1994 Sep 2. doi: 10.3109/10428199409056298
Publikations ID PMID: 7914128
 


MDR1 gene expression in primary colorectal carcinomas.
Autoren Pirker R, Wallner J, Gsur A, Götzl M, Zöchbauer S, Scheithauer W, Depisch D
Erscheinungsdaten British journal of cancer. 1993 Nov 15. pmc: PMC1968613
Publikations ID PMID: 8398695
 


Effective second line chemotherapy of advanced breast cancer with navelbine and mitomycin C.
Autoren Scheithauer W, Kornek G, Haider K, Kwasny W, Schenk T, Pirker R, Depisch D
Erscheinungsdaten Breast cancer research and treatment. 1993 Nov 16.
Publikations ID PMID: 8400323
 


MDR1 gene expression and treatment outcome in acute myeloid leukemia.
Autoren Pirker R, Wallner J, Geissler K, Linkesch W, Haas OA, Bettelheim P, Hopfner M, Scherrer R, Valent P, Havelec L
Erscheinungsdaten Journal of the National Cancer Institute. 1991 Jun 6.
Publikations ID PMID: 2023272
 


Expression of a multidrug resistance gene in blast crisis of chronic myelogenous leukemia.
Autoren Pirker R, Goldstein LJ, Ludwig H, Linkesch W, Lechner C, Gottesman MM, Pastan I
Erscheinungsdaten Cancer communications. 1990 Aug 23.
Publikations ID PMID: 2639725
 


Immunotoxins against solid tumors.
Autoren Pirker R
Erscheinungsdaten Journal of cancer research and clinical oncology. 1988 Oct 11.
Publikations ID PMID: 3045130
 


Third-generation epidermal growth factor receptor tyrosine kinase inhibitors in advanced nonsmall cell lung cancer.
Autoren Pirker R
Erscheinungsdaten Current opinion in oncology. 2015 Dec 30. doi: 10.1097/CCO.0000000000000260
Publikations ID PMID: 26720671
 


Cardiovascular biomarkers in patients with cancer and their association with all-cause mortality.
Autoren Pavo N, Raderer M, Hülsmann M, Neuhold S, Adlbrecht C, Strunk G, Goliasch G, Gisslinger H, Steger GG, Hejna M, Köstler W, Zöchbauer-Müller S, Marosi C, Kornek G, Auerbach L, Schneider S, Parschalk B, Scheithauer W, Pirker R, Drach J, Zielinski C, Pacher R
Erscheinungsdaten Heart (British Cardiac Society). 2015 Sep 28. pii: heartjnl-2015-307848. doi: 10.1136/heartjnl-2015-307848
Publikations ID PMID: 26416836
 


Alectinib in RET-rearranged non-small cell lung cancer-Another progress in precision medicine?
Autoren Pirker R, Filipits M
Erscheinungsdaten Translational lung cancer research. 2016 Jan 22. doi: 10.3978/j.issn.2218-6751.2015.03.08. pii: tlcr-04-06-797
Publikations ID PMID: 26798590
 


Prognostic Effect of Tumor Lymphocytic Infiltration in Resectable Non-Small-Cell Lung Cancer.
Autoren Brambilla E, Le Teuff G, Marguet S, Lantuejoul S, Dunant A, Graziano S, Pirker R, Douillard JY, Le Chevalier T, Filipits M, Rosell R, Kratzke R, Popper H, Soria JC, Shepherd FA, Seymour L, Tsao MS
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2016 Feb 1. pii: JCO.2015.63.0970. doi: 10.1200/JCO.2015.63.0970
Publikations ID PMID: 26834066
 


Prognostic and predictive effect of TP53 mutations in non-small cell lung cancer patients from adjuvant cisplatin-based therapy randomized trials: a LACE-bio pooled analysis.
Autoren Ma X, Le Teuff G, Lacas B, Tsao MS, Graziano S, Pignon JP, Douillard JY, Le Chevalier T, Seymour L, Filipits M, Pirker R, Janne P, Shepherd FA, Brambilla E, Soria JC, Hainaut P
Erscheinungsdaten Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2016 Feb 16. pii: S1556-0864(16)00359-2. doi: 10.1016/j.jtho.2016.02.002
Publikations ID PMID: 26899019
 


Personalized treatment of advanced non-small-cell lung cancer in routine clinical practice.
Autoren Pirker R, Filipits M
Erscheinungsdaten Cancer metastasis reviews. 2016 Mar 12. doi: 10.1007/s10555-016-9612-6. pii: 10.1007/s10555-016-9612-6
Publikations ID PMID: 26970967
 


Scientific Advances in Lung Cancer 2015.
Autoren Tsao AS, Scagliotti GV, Bunn PA, Carbone DP, Warren GW, Bai C, de Koning HJ, Yousaf-Khan AU, McWilliams A, Tsao MS, Adusumilli PS, Rami-Porta R, Asamura H, Van Schil PE, Darling GE, Ramalingam SS, Gomez DR, Rosenzweig KE, Zimmermann S, Peters S, Ignatius Ou SH, Reungwetwattana T, Jänne PA, Mok TS, Wakelee HA, Pirker R, Mazières J, Brahmer JR, Zhou Y, Herbst RS, Papadimitrakopoulou VA, Redman MW, Wynes MW, Gandara DR, Kelly RJ, Hirsch FR, Pass HI
Erscheinungsdaten Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2016 Mar 21. pii: S1556-0864(16)30022-3. doi: 10.1016/j.jtho.2016.03.012
Publikations ID PMID: 27013409
 


Cancer Control in Central and Eastern Europe: Current Situation and Recommendations for Improvement.
Autoren Vrdoljak E, Bodoky G, Jassem J, Popescu RA, Mardiak J, Pirker R, Čufer T, Bešlija S, Eniu A, Todorović V, Kubáčková K, Kurteva G, Tomašević Z, Sallaku A, Smichkoska S, Bajić Ž, Šikić BI
Erscheinungsdaten The oncologist. 2016 Jul 8. pii: theoncologist.2016-0137. doi: 10.1634/theoncologist.2016-0137
Publikations ID PMID: 27401890
 


Improving survival of patients with locally advanced non-small-cell cancer remains a challenge: comment to PROCLAIM.
Autoren Pirker R
Erscheinungsdaten Journal of thoracic disease. 2016 Aug 9. doi: 10.21037/jtd.2016.05.54. pii: jtd-08-07-E607
Publikations ID PMID: 27501237
 


IL-4 downregulates expression of the target receptor CD30 in neoplastic canine mast cells.
Autoren Bauer K, Hadzijusufovic E, Cerny-Reiterer S, Hoermann G, Reifinger M, Pirker A, Valent P, Willmann M
Erscheinungsdaten Veterinary and comparative oncology. 2016 Aug 9. doi: 10.1111/vco.12260
Publikations ID PMID: 27507155
 


From diagnosis to therapy in lung cancer: management of CT detected pulmonary nodules, a summary of the 2015 Chinese-German Lung Cancer Expert Panel.
Autoren Su C, Meyer M, Pirker R, Voigt W, Shi J, Pilz L, Huber RM, Wu Y, Wang J, He Y, Wang X, Zhang J, Zhi X, Shi M, Zhu B, Schoenberg SS, Henzler T, Manegold C, Zhou C, Roessner ED
Erscheinungsdaten Translational lung cancer research. 2016 Sep 21. doi: 10.21037/tlcr.2016.07.09. pii: tlcr-05-04-377
Publikations ID PMID: 27652202
 


Palliative care units in lung cancer in the real-world setting: a single institution's experience and its implications.
Autoren Masel EK, Schur S, Nemecek R, Mayrhofer M, Huber P, Adamidis F, Maehr B, Unseld M, Watzke HH, Pirker R
Erscheinungsdaten Annals of palliative medicine. pii: apm.2016.08.06. doi: 10.21037/apm.2016.08.06
Publikations ID PMID: 27701880
 


The European Society for Medical Oncology Magnitude of Clinical Benefit Scale in daily practice: a single institution, real-life experience at the Medical University of Vienna.
Autoren Kiesewetter B, Raderer M, Steger GG, Bartsch R, Pirker R, Zöchbauer-Müller S, Prager G, Krainer M, Preusser M, Schmidinger M, Zielinski CC
Erscheinungsdaten ESMO open. doi: 10.1136/esmoopen-2016-000066. pii: esmoopen-2016-000066
Publikations ID PMID: 27843624
 


An international, randomized, placebo-controlled, double-blind phase III study (MONET1) of motesanib plus carboplatin/paclitaxel (C/P) in patients with advanced nonsquamous non-small cell lung cancer (NSCLC).
Autoren Scagliotti G, Vynnychenko I, Ichinose Y, Park K, Kubota K, Blackhall FH, Pirker R, Galiulin R, Ciuleanu T, Sydorenko O, Dediu M, Papai-Szekely Z, Martinez Banaclocha N, McCoy S, Yao B, Hei YJ, Spigel DR
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2011 Jan 1. pii: 10.1200/jco.2011.29.18_suppl.lba7512
Publikations ID PMID: 27937148
 


MSH2 and adjuvant cisplatin-based chemotherapy in non-small cell lung cancer.
Autoren Fouret P, Planchard D, Mendiboure J, Kamal NS, Olaussen KA, Bertrand P, Pirker R, Dunant A, Le Chevalier T, Soria JC
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2009 Jan 1. pii: 10.1200/jco.2009.27.18_suppl.cra7502
Publikations ID PMID: 27937603
 


Efficacy of erlotinib in patients (pts) with advanced non-small-cell lung cancer (NSCLC) relative to clinical characteristics: Subset analyses from the TRUST study.
Autoren Allan SG, Bosquee L, Franke A, Pirker R, Scagliotti GV
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2008 Jan 1. pii: 10.1200/jco.2008.26.15_suppl.8081
Publikations ID PMID: 27948957
 


FLEX: A randomized, multicenter, phase III study of cetuximab in combination with cisplatin/vinorelbine (CV) versus CV alone in the first-line treatment of patients with advanced non-small cell lung cancer (NSCLC).
Autoren Pirker R, Szczesna A, von Pawel J, Krzakowski M, Ramlau R, Park K, Gatzemeier U, Bajeta E, Emig M, Pereira JR
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2008 Jan 1. pii: 10.1200/jco.2008.26.15_suppl.3
Publikations ID PMID: 27948496
 


Prognostic value of class III b-tubulin (TUBB3) in operable non-small cell lung cancer (NSCLC) and predictive value for adjuvant cisplatin-based chemotherapy (CT): A validation study on three randomized trials.
Autoren Reiman T, Seve P, Vataire A, Dunant A, Rosell R, Graziano S, Seymour L, Pirker R, Lai R
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2008 Jan 1. pii: 10.1200/jco.2008.26.15_suppl.7506
Publikations ID PMID: 27947282
 


Initial safety results of an expanded access program (EAP) of erlotinib in non-small cell lung cancer (NSCLC).
Autoren Reck M, Perng R, Groen H, Riska H, Pirker R, Sederholm C, Caspar C, Boyer M, Berzinec P, Allan S
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2006 Jan 1. pii: 10.1200/jco.2006.24.18_suppl.7190
Publikations ID PMID: 27953728
 


Cell cycle regulators and benefit of adjuvant chemotherapy in patients with non-small cell lung cancer.
Autoren Pirker R, Filipits M, Dunant A, Lantuejoul S, Schmid K, Huynh A, Soria J, Popper HH, Le Chevalier T, Brambilla E
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2006 Jan 1. pii: 10.1200/jco.2006.24.18_suppl.7100
Publikations ID PMID: 27953613
 


Phase III study comparing cisplatin/vinorelbine plus cetuximab versus cisplatin/vinorelbine as first-line treatment for patients with epidermal growth factor (EGFR)-expressing advanced non-small cell lung cancer (NSCLC) (FLEX).
Autoren Von Pawel J, Park K, Pereira JR, Szczesna A, Yu C, Ganul VL, Krzakowski M, Roh JK, Pilz K, Pirker R
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2006 Jan 1. pii: 10.1200/jco.2006.24.18_suppl.7109
Publikations ID PMID: 27953547
 


MSH2 and adjuvant cisplatin-based chemotherapy in non-small cell lung cancer.
Autoren Fouret P, Planchard D, Mendiboure J, Kamal NS, Olaussen KA, Bertrand P, Pirker R, Dunant A, Le Chevalier T, Soria JC
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2009 May 27. pii: 10.1200/jco.2009.27.15_suppl.cra7502
Publikations ID PMID: 27963172
 


Molecular and clinical predictors of outcome for cetuximab in non-small cell lung cancer (NSCLC): Data from the FLEX study.
Autoren O'Byrne KJ, Bondarenko I, Barrios C, Eschbach C, Martens U, Hotko Y, Kortsik C, Celik I, Stroh C, Pirker R
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2009 Jan 1. pii: 10.1200/jco.2009.27.15_suppl.8007
Publikations ID PMID: 27962785
 


Prognostic factors in advanced NSCLC: Experience from the FLEX trial.
Autoren Pirker R, Rodrigues-Pereira J, Szczesna A, Von Pawel J, Krzakowski M, Ramlau R, Vynnychenko I, Park K, Emig M, Gatzemeier U
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2009 Jan 1. pii: 10.1200/jco.2009.27.15_suppl.8083
Publikations ID PMID: 27962658
 


Use of immunohistochemical evaluation of DNA repair proteins to demonstrate cisplatin response prediction in resected NSCLC squamous cell carcinoma.
Autoren Pierceall WE, Sprott KM, Brambilla E, Pirker R, Popper HH, Wang X, Chen Y, Quan S, Filipits M, Alaparthi L, Kutok J, Weaver DT, Al-Adhami M, Andre F, Le Chevalier T, Ward BE, Soria J
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2011 Jan 1. pii: 10.1200/jco.2011.29.15_suppl.10579
Publikations ID PMID: 28021978
 


Rate of hemoglobin (Hb) decline from less than 10 g/dl to less than 9 g/dl in placebo-treated patients (pts) receiving chemotherapy: A pooled analysis of data from six randomized darbepoetin alfa trials.
Autoren Pirker R, Collins H, Legg JC, Vansteenkiste JF
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2011 Jan 1. pii: 10.1200/jco.2011.29.15_suppl.e19637
Publikations ID PMID: 28021779
 


An international, randomized, placebo-controlled, double-blind phase III study (MONET1) of motesanib plus carboplatin/paclitaxel (C/P) in patients with advanced nonsquamous non-small cell lung cancer (NSCLC).
Autoren Scagliotti G, Vynnychenko I, Ichinose Y, Park K, Kubota K, Blackhall FH, Pirker R, Galiulin R, Ciuleanu T, Sydorenko O, Dediu M, Papai-Szekely Z, Martinez Banaclocha N, McCoy S, Yao B, Hei YJ, Spigel DR
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2011 Jan 1. pii: 10.1200/jco.2011.29.15_suppl.lba7512
Publikations ID PMID: 28020760
 


A phase II study of pegfilgrastim to support ACE 14 chemotherapy for the treatment of subjects with small cell lung cancer (SCLC; extensive disease).
Autoren Pirker R, Ulsperger E, Aigner K, Messner J
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2005 Jan 1. pii: 10.1200/jco.2004.22.14_suppl.7216
Publikations ID PMID: 28013814
 


PD-L1 protein expression assessed by immunohistochemistry is neither prognostic nor predictive of benefit from adjuvant chemotherapy in resected non-small cell lung cancer.
Autoren Tsao MS, Le Teuff G, Shepherd FA, Landais C, Hainaut P, Filipits M, Pirker R, Le Chevalier T, Graziano S, Kratze R, Soria JC, Pignon JP, Seymour L, Brambilla E
Erscheinungsdaten Annals of oncology : official journal of the European Society for Medical Oncology. 2017 Jan 30. pii: mdx003. doi: 10.1093/annonc/mdx003
Publikations ID PMID: 28137741
 


1499PEFFECTIVENESS OF DARBEPOETIN ALFA (DA) FOR CHEMOTHERAPY-INDUCED ANAEMIA (CIA) WHEN INITIATED AT HAEMOGLOBIN (HB) ≤10 G/DL.
Autoren Pirker R, Vansteenkiste JF, Hedenus M, Hernandez E, Belton L, Terwey J
Erscheinungsdaten Annals of oncology : official journal of the European Society for Medical Oncology. 2017 Feb 7. pii: 2242185. doi: 10.1093/annonc/mdu356.20
Publikations ID PMID: 28172008
 


167OPROGNOSTIC AND PREDICTIVE BIOMARKERS FOR ACT (ADJUVANT CHEMOTHERAPY) IN RESECTED NON-SMALL CELL LUNG CANCER (R-NSCLC): LACE-BIO.
Autoren Seymour LK, Le Teuff G, Tsao M, Brambilla E, Shepherd F, Soria J, Kratzke R, Graziano S, Douillard J, Rosell R, Reiman A, Lacas B, Bourredjem A, Le Chevalier T, Pirker R, Filipits M, Hainaut P, Janne PA, Pignon J
Erscheinungsdaten Annals of oncology : official journal of the European Society for Medical Oncology. 2017 Feb 7. pii: 2238214. doi: 10.1093/annonc/mdu326.1
Publikations ID PMID: 28170565
 


Milestones in the systemic treatment of lung cancer.
Autoren Pirker R
Erscheinungsdaten Memo. 2017 Feb 6. doi: 10.1007/s12254-017-0313-9. pii: 313. pmc: PMC5357246
Publikations ID PMID: 28367252
 


Molecular Biomarkers in Advanced Non-Small-Cell Lung Cancer: A Rapidly Changing Field.
Autoren Pirker R
Erscheinungsdaten Journal of oncology practice. 2017 Apr 11. doi: 10.1200/JOP.2017.022780
Publikations ID PMID: 28399383
 


Subclinical involvement of the liver is associated with prognosis in treatment naïve cancer patients.
Autoren Pavo N, Raderer M, Goliasch G, Wurm R, Strunk G, Cho A, Novak JF, Gisslinger H, Steger GG, Hejna M, Köstler W, Zöchbauer-Müller S, Marosi C, Kornek G, Auerbach L, Schneider ST, Parschalk B, Scheithauer W, Pirker R, Kiesewetter B, Pacher R, Zielinski C, Hülsmann M
Erscheinungsdaten Oncotarget. 2017 Apr 16. pii: 17131. doi: 10.18632/oncotarget.17131
Publikations ID PMID: 28465470
 


Pooled Analysis of the Prognostic and Predictive Effects of TP53 Comutation Status Combined With KRAS or EGFR Mutation in Early-Stage Resected Non-Small-Cell Lung Cancer in Four Trials of Adjuvant Chemotherapy.
Autoren Shepherd FA, Lacas B, Le Teuff G, Hainaut P, Jänne PA, Pignon JP, Le Chevalier T, Seymour L, Douillard JY, Graziano S, Brambilla E, Pirker R, Filipits M, Kratzke R, Soria JC, Tsao MS
Erscheinungsdaten Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2017 Apr 28. doi: 10.1200/JCO.2016.71.2893
Publikations ID PMID: 28453411
 


Trimodality therapy for Pancoast tumors: T4 is not a contraindication to radical surgery.
Autoren Waseda R, Klikovits T, Hoda MA, Hoetzenecker K, Bertoglio P, Dieckmann K, Zöchbauer-Müller S, Pirker R, Prosch H, Döme B, Klepetko W
Erscheinungsdaten Journal of surgical oncology. 2017 Apr 13. doi: 10.1002/jso.24629
Publikations ID PMID: 28407246
 


Subclinical involvement of the liver is associated with prognosis in treatment naïve cancer patients.
Autoren Pavo N, Raderer M, Goliasch G, Wurm R, Strunk G, Cho A, Novak JF, Gisslinger H, Steger GG, Hejna M, Köstler W, Zöchbauer-Müller S, Marosi C, Kornek G, Auerbach L, Schneider ST, Parschalk B, Scheithauer W, Pirker R, Kiesewetter B, Pacher R, Zielinski C, Hülsmann M
Erscheinungsdaten Oncotarget. 2017 Apr 16. doi: 10.18632/oncotarget.17131. pii: 17131. pmc: PMC5655279
Publikations ID PMID: 29113384
 


EGFR monoclonal antibody biomarkers in advanced NSCLC: from translational research to clinical implementation.
Autoren Pirker R
Erscheinungsdaten The Lancet. Oncology. 2017 Nov 20. pii: S1470-2045(17)30873-2. doi: 10.1016/S1470-2045(17)30873-2
Publikations ID PMID: 29169876
 


EGFR tyrosine kinase inhibitors as first-line therapy in advanced EGFR mutation-positive non-small cell lung cancer: strategies to improve clinical outcome.
Autoren Tiefenbacher A, Pirker R
Erscheinungsdaten Journal of thoracic disease. doi: 10.21037/jtd.2017.10.02. pii: jtd-09-11-4208. pmc: PMC5720983
Publikations ID PMID: 29268473
 


Novel active agents in patients with advanced NSCLC without driver mutations who have progressed after first-line chemotherapy.
Autoren Manegold C, Adjei A, Bussolino F, Cappuzzo F, Crino L, Dziadziuszko R, Ettinger D, Fennell D, Kerr K, Le Chevalier T, Leighl N, Papotti M, Paz-Ares L, Pérol M, Peters S, Pirker R, Quoix E, Reck M, Smit E, Vokes E, van Zandwijk N, Zhou C
Erscheinungsdaten ESMO open. 2017 Jan 13. doi: 10.1136/esmoopen-2016-000118. pii: esmoopen-2016-000118. pmc: PMC5729303
Publikations ID PMID: 29435365
 


Cell-free plasma DNA-guided treatment with osimertinib in patients with advanced EGFR-mutated NSCLC.
Autoren Buder A, Hochmair MJ, Schwab S, Bundalo T, Schenk P, Errhalt P, Mikes RE, Absenger G, Patocka K, Baumgartner B, Setinek U, Burghuber OC, Prosch H, Pirker R, Filipits M
Erscheinungsdaten Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2018 Mar 2. pii: S1556-0864(18)30167-9. doi: 10.1016/j.jtho.2018.02.014
Publikations ID PMID: 29505901
 


Automatic ictal onset source localization in presurgical epilepsy evaluation.
Autoren Koren J, Gritsch G, Pirker S, Herta J, Perko H, Kluge T, Baumgartner C
Erscheinungsdaten Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2018 Apr 6. pii: S1388-2457(18)30276-1. doi: 10.1016/j.clinph.2018.03.020
Publikations ID PMID: 29680731
 


Frequency, risk factors, and impact on mortality of arterial thromboembolism in patients with cancer.
Autoren Grilz E, Königsbrügge O, Posch F, Schmidinger M, Pirker R, Lang IM, Pabinger I, Ay C
Erscheinungsdaten Haematologica. 2018 May 24. pii: haematol.2018.192419. doi: 10.3324/haematol.2018.192419
Publikations ID PMID: 29794142
 


IASLC Statement Paper: Liquid Biopsy for Advanced Non-Small Cell Lung Cancer (NSCLC).
Autoren Rolfo C, Mack PC, Scagliotti GV, Baas P, Barlesi F, Bivona TG, Herbst RS, Mok TS, Peled N, Pirker R, Raez LE, Reck M, Riess JW, Sequist LV, Shepherd FA, Sholl LM, Tan DS, Wakelee HA, Wistuba II, Wynes MW, Carbone DP, Hirsch FR, Gandara DR
Erscheinungsdaten Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2018 Jun 6. pii: S1556-0864(18)30680-4. doi: 10.1016/j.jtho.2018.05.030
Publikations ID PMID: 29885479
 


Automated Long-Term EEG Review: Fast and Precise Analysis in Critical Care Patients.
Autoren Koren JP, Herta J, Fürbass F, Pirker S, Reiner-Deitemyer V, Riederer F, Flechsenhar J, Hartmann M, Kluge T, Baumgartner C
Erscheinungsdaten Frontiers in neurology. 2018 Jun 19. doi: 10.3389/fneur.2018.00454. pmc: PMC6020775
Publikations ID PMID: 29973906
 


Systemic treatment of advanced non-small cell lung cancer: controversies and perspectives.
Autoren Tiefenbacher A, Pirker R
Erscheinungsdaten Memo. 2018 May 18. doi: 10.1007/s12254-018-0408-y. pii: 408. pmc: PMC6006273
Publikations ID PMID: 29983826
 


Effect of Anlotinib as a Third-Line or Further Treatment on Overall Survival of Patients With Advanced Non-Small Cell Lung Cancer: The ALTER 0303 Phase 3 Randomized Clinical Trial.
Autoren Han B, Li K, Wang Q, Zhang L, Shi J, Wang Z, Cheng Y, He J, Shi Y, Zhao Y, Yu H, Zhao Y, Chen W, Luo Y, Wu L, Wang X, Pirker R, Nan K, Jin F, Dong J, Li B, Sun Y
Erscheinungsdaten JAMA oncology. 2018 Aug 9. pii: 2696341. doi: 10.1001/jamaoncol.2018.3039
Publikations ID PMID: 30098152
 


Is smoking history the truly best biomarker for immune checkpoint inhibitor treatment in advanced non-small cell lung cancer?
Autoren Pirker R
Erscheinungsdaten ESMO open. 2018 Aug 10. doi: 10.1136/esmoopen-2018-000421. pii: esmoopen-2018-000421. pmc: PMC6088342
Publikations ID PMID: 30116594
 


Expenditures on Oncology Drugs and Cancer Mortality-to-Incidence Ratio in Central and Eastern Europe.
Autoren Vrdoljak E, Bodoky G, Jassem J, Popescu R, Pirker R, Čufer T, Bešlija S, Eniu A, Todorović V, Kopečková K, Kurteva G, Tomašević Z, Sallaku A, Smichkoska S, Bajić Ž, Sikic B
Erscheinungsdaten The oncologist. 2018 Sep 4. pii: theoncologist.2018-0093. doi: 10.1634/theoncologist.2018-0093
Publikations ID PMID: 30181313
 


PD-1 and PD-L1 Protein Expression Predict Survival in Completely Resected Lung Adenocarcinoma.
Autoren Zaric B, Brcic L, Buder A, Brandstetter A, Buresch JO, Traint S, Kovacevic T, Stojsic V, Perin B, Pirker R, Filipits M
Erscheinungsdaten Clinical lung cancer. 2018 Aug 22. pii: S1525-7304(18)30208-0. doi: 10.1016/j.cllc.2018.08.014
Publikations ID PMID: 30197262
 


Treatment of Advanced Non-Small-Cell Lung Cancer: From Chemotherapy to Chemoimmunotherapy.
Autoren Pirker R
Erscheinungsdaten Journal of oncology practice. doi: 10.1200/JOP.18.00474
Publikations ID PMID: 30205773
 


The role of ethnic tourism in the food knowledge tradition of Tyrolean migrants in Treze Tílias, SC, Brazil.
Autoren Kuhn E, Haselmair R, Pirker H, Vogl CR
Erscheinungsdaten Journal of ethnobiology and ethnomedicine. 2018 Apr 6. doi: 10.1186/s13002-018-0224-9. pii: 10.1186/s13002-018-0224-9. pmc: PMC5889527
Publikations ID PMID: 29625616
 


Adjuvant Therapy in Patients With Completely Resected Non-small-cell Lung Cancer: Current Status and Perspectives.
Autoren Pirker R, Filipits M
Erscheinungsdaten Clinical lung cancer. 2018 Sep 24. pii: S1525-7304(18)30261-4. doi: 10.1016/j.cllc.2018.09.016
Publikations ID PMID: 30309777
 


Management of stage IA -mutant adenocarcinoma of the lung.
Autoren Pirker R
Erscheinungsdaten Journal of thoracic disease. doi: 10.21037/jtd.2018.08.70. pii: jtd-10-S26-S3260. pmc: PMC6186648
Publikations ID PMID: 30370132
 


LACE-Bio: Validation of Predictive and/or Prognostic Immunohistochemistry/Histochemistry-based Biomarkers in Resected Non-small-cell Lung Cancer.
Autoren Seymour L, Le Teuff G, Brambilla E, Shepherd FA, Soria JC, Kratzke R, Graziano S, Douillard JY, Rosell R, Reiman A, Lacas B, Lueza B, Aviel-Ronen S, McLeer A, Le Chevalier T, Pirker R, Filipits M, Dunant A, Pignon JP, Tsao MS
Erscheinungsdaten Clinical lung cancer. 2018 Oct 11. pii: S1525-7304(18)30262-6. doi: 10.1016/j.cllc.2018.10.001
Publikations ID PMID: 30414783
 


Biomarkers for immune checkpoint inhibitors in advanced nonsmall cell lung cancer.
Autoren Pirker R
Erscheinungsdaten Current opinion in oncology. 2018 Nov 9. doi: 10.1097/CCO.0000000000000496
Publikations ID PMID: 30418192
 


EGFR Mutations in Cell-free Plasma DNA from Patients with Advanced Lung Adenocarcinoma: Improved Detection by Droplet Digital PCR.
Autoren Buder A, Setinek U, Hochmair MJ, Schwab S, Kirchbacher K, Keck A, Burghuber OC, Pirker R, Filipits M
Erscheinungsdaten Targeted oncology. 2019 Feb 27. doi: 10.1007/s11523-019-00623-x. pii: 10.1007/s11523-019-00623-x
Publikations ID PMID: 30810887
 


Systemic therapy of elderly patients with advanced non-small cell lung cancer-individualized treatment is key.
Autoren Pirker R
Erscheinungsdaten Annals of translational medicine. doi: 10.21037/atm.2019.03.10. pii: atm-07-S1-S48. pmc: PMC6462625
Publikations ID PMID: 31032327
 


From crizotinib to lorlatinib: continuous improvement in precision treatment of ALK-positive non-small cell lung cancer.
Autoren Pirker R, Filipits M
Erscheinungsdaten ESMO open. 2019 Sep 8. doi: 10.1136/esmoopen-2019-000548. pii: esmoopen-2019-000548. pmc: PMC6735665
Publikations ID PMID: 31555485
 


Chemotherapy remains a cornerstone in the treatment of nonsmall cell lung cancer.
Autoren Pirker R
Erscheinungsdaten Current opinion in oncology. 2019 Oct 9. doi: 10.1097/CCO.0000000000000592
Publikations ID PMID: 31599771
 


Individualizing treatment of nonsmall cell lung cancer.
Autoren Pirker R
Erscheinungsdaten Current opinion in oncology. 2019 Oct 24. doi: 10.1097/CCO.0000000000000597
Publikations ID PMID: 31652144
 


Presurgical epilepsy evaluation and epilepsy surgery.
Autoren Baumgartner C, Koren JP, Britto-Arias M, Zoche L, Pirker S
Erscheinungsdaten F1000Research. 2019 Oct 29. doi: 10.12688/f1000research.17714.1. pmc: PMC6820825
Publikations ID PMID: 31700611
 


Beyond tissue biopsy: a diagnostic framework to address tumor heterogeneity in lung cancer.
Autoren Voigt W, Manegold C, Pilz L, Wu YL, Müllauer L, Pirker R, Filipits M, Niklinski J, Petruzelka L, Prosch H
Erscheinungsdaten Current opinion in oncology. 2019 Nov 9. doi: 10.1097/CCO.0000000000000598
Publikations ID PMID: 31714259
 


Cisplatin benefit is predicted by immunohistochemical analysis of DNA repair proteins in squamous cell carcinoma but not adenocarcinoma: theranostic modeling by NSCLC constituent histological subclasses.
Autoren Pierceall WE, Olaussen KA, Rousseau V, Brambilla E, Sprott KM, Andre F, Pignon JP, Le Chevalier T, Pirker R, Jiang C, Filipits M, Chen Y, Kutok JL, Weaver DT, Ward BE, Soria JC
Erscheinungsdaten Annals of oncology : official journal of the European Society for Medical Oncology. 2019 Dec 4. pii: S0923-7534(19)35194-4. doi: 10.1093/annonc/mdr624
Publikations ID PMID: 32018692
 


Third CECOG consensus on the systemic treatment of non-small-cell lung cancer.
Autoren Brodowicz T, Ciuleanu T, Crawford J, Filipits M, Fischer JR, Georgoulias V, Gridelli C, Hirsch FR, Jassem J, Kosmidis P, Krzakowski M, Manegold C, Pujol JL, Stahel R, Thatcher N, Vansteenkiste J, Minichsdorfer C, Zöchbauer-Müller S, Pirker R, Zielinski CC
Erscheinungsdaten Annals of oncology : official journal of the European Society for Medical Oncology. 2019 Dec 4. pii: S0923-7534(19)34677-0. doi: 10.1093/annonc/mdr381
Publikations ID PMID: 32018580
 


Conquering lung cancer: current status and prospects for the future.
Autoren Pirker R
Erscheinungsdaten Pulmonology. 2020 Mar 18. pii: S2531-0437(20)30031-3. doi: 10.1016/j.pulmoe.2020.02.005
Publikations ID PMID: 32199906
 


mutation tracking predicts survival in advanced -mutated non-small cell lung cancer patients treated with osimertinib.
Autoren Buder A, Hochmair MJ, Setinek U, Pirker R, Filipits M
Erscheinungsdaten Translational lung cancer research. doi: 10.21037/tlcr.2020.03.02. pii: tlcr-09-02-239. pmc: PMC7225165
Publikations ID PMID: 32420063
 


Care of patients with non-small-cell lung cancer stage III - the Central European real-world experience.
Autoren Zemanova M, Pirker R, Petruzelka L, Zbozínkova Z, Jovanovic D, Rajer M, Bogos K, Purkalne G, Ceriman V, Chaudhary S, Richter I, Kufa J, Jakubikova L, Zemaitis M, Cernovska M, Koubkova L, Vilasova Z, Dieckmann K, Farkas A, Spasic J, Fröhlich K, Tiefenbacher A, Hollosi V, Kultan J, Kolarová I, Votruba J
Erscheinungsdaten Radiology and oncology. 2020 May 28. doi: 10.2478/raon-2020-0026. pii: /j/raon.2020.54.issue-2/raon-2020-0026/raon-2020-0026.xml
Publikations ID PMID: 32463394
 


ERCC1 influence on the incidence of brain metastases in patients with non-squamous NSCLC treated with adjuvant cisplatin-based chemotherapy.
Autoren Besse B, Massard C, Haddad V, Andre F, Dunant A, Pirker R, Olaussen KA, Brambilla E, Fouret P, Soria JC
Erscheinungsdaten Annals of oncology : official journal of the European Society for Medical Oncology. 2010 Aug 26. pii: S0923-7534(19)38607-7. doi: 10.1093/annonc/mdq407
Publikations ID PMID: 20801905
 


Cisplatin benefit is predicted by immunohistochemical analysis of DNA repair proteins in squamous cell carcinoma but not adenocarcinoma: theranostic modeling by NSCLC constituent histological subclasses.
Autoren Pierceall WE, Olaussen KA, Rousseau V, Brambilla E, Sprott KM, Andre F, Pignon JP, Le Chevalier T, Pirker R, Jiang C, Filipits M, Chen Y, Kutok JL, Weaver DT, Ward BE, Soria JC
Erscheinungsdaten Annals of oncology : official journal of the European Society for Medical Oncology. 2012 Jan 23. pii: S0923-7534(19)35194-4. doi: 10.1093/annonc/mdr624
Publikations ID PMID: 22269178
 


Effects of CERA (continuous erythropoietin receptor activator) in patients with advanced non-small-cell lung cancer (NSCLC) receiving chemotherapy: results of a phase II study.
Autoren Gascon P, Pirker R, Del Mastro L, Durrwell L
Erscheinungsdaten Annals of oncology : official journal of the European Society for Medical Oncology. 2010 Mar 24. pii: S0923-7534(19)39577-8. doi: 10.1093/annonc/mdq073
Publikations ID PMID: 20335369
 


Immunotherapy combinations in advanced nonsmall cell lung cancer.
Autoren Pirker R
Erscheinungsdaten Current opinion in oncology. 2020 Nov 11. doi: 10.1097/CCO.0000000000000700
Publikations ID PMID: 33186185
 


The impact of hippocampal impairment on task-positive and task-negative language networks in temporal lobe epilepsy.
Autoren Nenning KH, Fösleitner O, Schwartz E, Schwarz M, Schmidbauer V, Geisl G, Widmann C, Pirker S, Baumgartner C, Prayer D, Pataraia E, Bartha-Doering L, Langs G, Kasprian G, Bonelli SB
Erscheinungsdaten Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2020 Dec 3. pii: S1388-2457(20)30578-2. doi: 10.1016/j.clinph.2020.10.031
Publikations ID PMID: 33450563
 


Lung Cancer in Austria.
Autoren Pirker R, Prosch H, Popper H, Klepetko W, Dieckmann K, Burghuber OC, Klikovits T, Hoda MA, Zöchbauer-Müller S, Filipits M
Erscheinungsdaten Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. pii: S1556-0864(20)31049-2. doi: 10.1016/j.jtho.2020.10.158
Publikations ID PMID: 33896572
 


Lung cancer: continuous progress in diagnosis and treatment.
Autoren Pirker R, Zhou C
Erscheinungsdaten Current opinion in oncology. 2021 Oct 27. doi: 10.1097/CCO.0000000000000809. pii: 00001622-900000000-98962
Publikations ID PMID: 34710885
 


Increased expression of GABA receptor subunits associated with tonic inhibition in patients with temporal lobe epilepsy.
Autoren Sperk G, Pirker S, Gasser E, Wieselthaler A, Bukovac A, Kuchukhidze G, Maier H, Drexel M, Baumgartner C, Ortler M, Czech T
Erscheinungsdaten Brain communications. 2021 Oct 12. doi: 10.1093/braincomms/fcab239. pii: fcab239. pmc: PMC8545616
Publikations ID PMID: 34708207
 


Dairy Intake and Parkinson's Disease: A Mendelian Randomization Study.
Autoren Domenighetti C, Sugier PE, Ashok Kumar Sreelatha A, Schulte C, Grover S, Mohamed O, Portugal B, May P, Bobbili DR, Radivojkov-Blagojevic M, Lichtner P, Singleton AB, Hernandez DG, Edsall C, Mellick GD, Zimprich A, Pirker W, Rogaeva E, Lang AE, Koks S, Taba P, Lesage S, Brice A, Corvol JC, Chartier-Harlin MC, Mutez E, Brockmann K, Deutschländer AB, Hadjigeorgiou GM, Dardiotis E, Stefanis L, Simitsi AM, Valente EM, Petrucci S, Duga S, Straniero L, Zecchinelli A, Pezzoli G, Brighina L, Ferrarese C, Annesi G, Quattrone A, Gagliardi M, Matsuo H, Kawamura Y, Hattori N, Nishioka K, Chung SJ, Kim YJ, Kolber P, van de Warrenburg BPC, Bloem BR, Aasly J, Toft M, Pihlstrøm L, Correia Guedes L, Ferreira JJ, Bardien S, Carr J, Tolosa E, Ezquerra M, Pastor P, Diez-Fairen M, Wirdefeldt K, Pedersen NL, Ran C, Belin AC, Puschmann A, Hellberg C, Clarke CE, Morrison KE, Tan M, Krainc D, Burbulla LF, Farrer MJ, Krüger R, Gasser T, Sharma M, Elbaz A
Erscheinungsdaten Movement disorders : official journal of the Movement Disorder Society. 2022 Jan 8. doi: 10.1002/mds.28902
Publikations ID PMID: 34997937
 


Anti-Neuronal IgG4 Autoimmune Diseases and IgG4-Related Diseases May Not Be Part of the Same Spectrum: A Comparative Study.
Autoren Endmayr V, Tunc C, Ergin L, De Rosa A, Weng R, Wagner L, Yu TY, Fichtenbaum A, Perkmann T, Haslacher H, Kozakowski N, Schwaiger C, Ricken G, Hametner S, Klotz S, Dutra LA, Lechner C, de Simoni D, Poppert KN, Müller GJ, Pirker S, Pirker W, Angelovski A, Valach M, Maestri M, Guida M, Ricciardi R, Frommlet F, Sieghart D, Pinter M, Kircher K, Artacker G, Höftberger R, Koneczny I
Erscheinungsdaten Frontiers in immunology. 2022 Jan 14. doi: 10.3389/fimmu.2021.785247. pmc: PMC8795769
Publikations ID PMID: 35095860
 


Imaging visuospatial memory in temporal lobe epilepsy-Results of an fMRI study.
Autoren Schmidbauer V, Nenning KH, Schwarz M, Foesleitner O, Mayr-Geisl G, Yildirim MS, Pirker S, Moser D, Denk D, Prayer D, Trimmel K, Langs G, Baumgartner C, Pataraia E, Kasprian G, Bonelli S
Erscheinungsdaten PloS one. 2022 Feb 22. doi: 10.1371/journal.pone.0264349. pii: PONE-D-21-24949
Publikations ID PMID: 35192676
 


The cancer survival index-A prognostic score integrating psychosocial and biological factors in patients diagnosed with cancer or haematologic malignancies.
Autoren Gaiger A, Lubowitzki S, Krammer K, Zeilinger EL, Acel A, Cenic O, Schrott A, Unseld M, Rassoulian AP, Skrabs C, Valent P, Gisslinger H, Marosi C, Preusser M, Prager G, Kornek G, Pirker R, Steger GG, Bartsch R, Raderer M, Simonitsch-Klupp I, Thalhammer R, Zielinski C, Jäger U
Erscheinungsdaten Cancer medicine. 2022 Mar 22. doi: 10.1002/cam4.4697
Publikations ID PMID: 35315594
 


Automatic seizure detection and seizure pattern morphology.
Autoren Elezi L, Koren JP, Pirker S, Baumgartner C
Erscheinungsdaten Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2022 Mar 18. pii: S1388-2457(22)00206-1. doi: 10.1016/j.clinph.2022.02.027
Publikations ID PMID: 35382982
 


Genome-wide Association and Meta-analysis of Age-at-Onset in Parkinson Disease: Evidence From COURAGE-PD Consortium.
Autoren Grover S, Ashwin AKS, Pihlstrom L, Domenighetti C, Schulte C, Sugier PE, Radivojkov-Blagojevic M, Lichtner P, Mohamed O, Portugal B, Landoulsi Z, May P, Bobbili D, Edsall C, Bartusch F, Hanussek M, Krüger J, Hernandez DG, Blauwendraat C, Mellick GD, Zimprich A, Pirker W, Tan M, Rogaeva E, Lang A, Koks S, Taba P, Lesage S, Brice A, Corvol JC, Chartier-Harlin MC, Mutez E, Brockmann K, Deutschländer AB, Hadjigeorgiou GM, Dardiotis E, Stefanis L, Simitsi AM, Valente EM, Petrucci S, Straniero L, Zecchinelli A, Pezzoli G, Brighina L, Ferrarese C, Annesi G, Quattrone A, Gagliardi M, Burbulla LF, Matsuo H, Kawamura Y, Hattori N, Nishioka K, Chung SJ, Kim YJ, Pavelka L, van de Warrenburg BP, Bloem BR, Singleton AB, Aasly J, Toft M, Guedes LC, Ferreira JJ, Bardien S, Carr J, Tolosa E, Ezquerra M, Pastor P, Diez-Fairen M, Wirdefeldt K, Pedersen NL, Ran C, Belin AC, Puschmann A, Hellberg C, Clarke CE, Morrison KE, Krainc D, Farrer MJ, Kruger R, Elbaz A, Gasser T, Sharma M
Erscheinungsdaten Neurology. 2022 May 26. pii: WNL.0000000000200699. doi: 10.1212/WNL.0000000000200699
Publikations ID PMID: 35618440
 


The Interaction between HLA-DRB1 and Smoking in Parkinson's Disease Revisited.
Autoren Domenighetti C, Douillard V, Sugier PE, Sreelatha AAK, Schulte C, Grover S, May P, Bobbili DR, Radivojkov-Blagojevic M, Lichtner P, Singleton AB, Hernandez DG, Edsall C, Gourraud PA, Mellick GD, Zimprich A, Pirker W, Rogaeva E, Lang AE, Koks S, Taba P, Lesage S, Brice A, Corvol JC, Chartier-Harlin MC, Mutez E, Brockmann K, Deutschländer AB, Hadjigeorgiou GM, Dardiotis E, Stefanis L, Simitsi AM, Valente EM, Petrucci S, Duga S, Straniero L, Zecchinelli A, Pezzoli G, Brighina L, Ferrarese C, Annesi G, Quattrone A, Gagliardi M, Matsuo H, Nakayama A, Hattori N, Nishioka K, Chung SJ, Kim YJ, Kolber P, van de Warrenburg BPC, Bloem BR, Aasly J, Toft M, Pihlstrøm L, Correia Guedes L, Ferreira JJ, Bardien S, Carr J, Tolosa E, Ezquerra M, Pastor P, Diez-Fairen M, Wirdefeldt K, Pedersen NL, Ran C, Belin AC, Puschmann A, Ygland Rödström E, Clarke CE, Morrison KE, Tan M, KraincMD D, Burbulla LF, Farrer MJ, Krüger R, Gasser T, Sharma M, Vince N, Elbaz A
Erscheinungsdaten Movement disorders : official journal of the Movement Disorder Society. 2022 Jul 10. doi: 10.1002/mds.29133
Publikations ID PMID: 35810454
 


Genome-wide Association and Meta-analysis of Age at Onset in Parkinson Disease: Evidence From the COURAGE-PD Consortium.
Autoren Grover S, Kumar Sreelatha AA, Pihlstrom L, Domenighetti C, Schulte C, Sugier PE, Radivojkov-Blagojevic M, Lichtner P, Mohamed O, Portugal B, Landoulsi Z, May P, Bobbili D, Edsall C, Bartusch F, Hanussek M, Krüger J, Hernandez DG, Blauwendraat C, Mellick GD, Zimprich A, Pirker W, Tan M, Rogaeva E, Lang A, Koks S, Taba P, Lesage S, Brice A, Corvol JC, Chartier-Harlin MC, Mutez E, Brockmann K, Deutschländer AB, Hadjigeorgiou GM, Dardiotis E, Stefanis L, Simitsi AM, Valente EM, Petrucci S, Straniero L, Zecchinelli A, Pezzoli G, Brighina L, Ferrarese C, Annesi G, Quattrone A, Gagliardi M, Burbulla LF, Matsuo H, Kawamura Y, Hattori N, Nishioka K, Chung SJ, Kim YJ, Pavelka L, van de Warrenburg BPC, Bloem BR, Singleton AB, Aasly J, Toft M, Guedes LC, Ferreira JJ, Bardien S, Carr J, Tolosa E, Ezquerra M, Pastor P, Diez-Fairen M, Wirdefeldt K, Pedersen NL, Ran C, Belin AC, Puschmann A, Hellberg C, Clarke CE, Morrison KE, Krainc D, Farrer MJ, Kruger R, Elbaz A, Gasser T, Sharma M
Erscheinungsdaten Neurology. 2022 May 26. pii: WNL.0000000000200699. doi: 10.1212/WNL.0000000000200699
Publikations ID PMID: 35970579
 


Temporal Trends of Functional Outcome in Patients With Acute Ischemic Stroke Treated With Intravenous Thrombolysis.
Autoren Marko M, Miksova D, Ebner J, Lang M, Serles W, Sommer P, Sykora M, Lang W, Knoflach M, Kiechl S, Greisenegger S
Erscheinungsdaten Stroke. 2022 Aug 24. doi: 10.1161/STROKEAHA.121.038400
Publikations ID PMID: 36000395
 


Costs of Epilepsy in Austria: Unemployment as a primary driving factor.
Autoren Pirker S, Graef A, Gächter M, Baumgartner C
Erscheinungsdaten Seizure. 2021 Apr 30. doi: 10.1016/j.seizure.2021.04.020. pii: S1059-1311(21)00137-0
Publikations ID PMID: 33975079
 


Investigation of Shared Genetic Risk Factors Between Parkinson's Disease and Cancers.
Autoren Sugier PE, Lucotte EA, Domenighetti C, Law MH, Iles MM, Brown K, Amos C, McKay JD, Hung RJ, Karimi M, Bacq-Daian D, Boland-Augé A, Olaso R, Deleuze JF, Lesueur F, Ostroumova E, Kesminiene A, de Vathaire F, Guénel P, Sreelatha AAK, Schulte C, Grover S, May P, Bobbili DR, Radivojkov-Blagojevic M, Lichtner P, Singleton AB, Hernandez DG, Edsall C, Mellick GD, Zimprich A, Pirker W, Rogaeva E, Lang AE, Koks S, Taba P, Lesage S, Brice A, Corvol JC, Chartier-Harlin MC, Mutez E, Brockmann K, Deutschländer AB, Hadjigeorgiou GM, Dardiotis E, Stefanis L, Simitsi AM, Valente EM, Petrucci S, Straniero L, Zecchinelli A, Pezzoli G, Brighina L, Ferrarese C, Annesi G, Quattrone A, Gagliardi M, Matsuo H, Nakayama A, Hattori N, Nishioka K, Chung SJ, Kim YJ, Kolber P, van de Warrenburg BPC, Bloem BR, Aasly J, Toft M, Pihlstrøm L, Guedes LC, Ferreira JJ, Bardien S, Carr J, Tolosa E, Ezquerra M, Pastor P, Diez-Fairen M, Wirdefeldt K, Pedersen N, Ran C, Belin AC, Puschmann A, Rödström EY, Clarke CE, Morrison KE, Tan M, Krainc D, Burbulla LF, Farrer MJ, Kruger R, Gasser T, Sharma M, Truong T, Elbaz A
Erscheinungsdaten Movement disorders : official journal of the Movement Disorder Society. 2023 Feb 14. doi: 10.1002/mds.29337
Publikations ID PMID: 36788297
 


Pharmacological Treatment of Tremor in Parkinson's Disease Revisited.
Autoren Pirker W, Katzenschlager R, Hallett M, Poewe W
Erscheinungsdaten Journal of Parkinson's disease. 2023 Feb 21. doi: 10.3233/JPD-225060. pii: JPD225060
Publikations ID PMID: 36847017
 


Elevated urine BMP phospholipids in LRRK2 and VPS35 mutation carriers with and without Parkinson's disease.
Autoren Gomes S, Garrido A, Tonelli F, Obiang D, Tolosa E, Martí MJ, Ruiz-Martínez J, Vinagre-Aragón A, Hernandez-Eguiazu H, Croitoru I, Marshall VL, Koenig T, Hotzy C, Hsieh F, Sakalosh M, Tengstrand E, Padmanabhan S, Merchant K, Bruecke C, Pirker W, Zimprich A, Sammler E
Erscheinungsdaten NPJ Parkinson's disease. 2023 Apr 4. doi: 10.1038/s41531-023-00482-4. pii: 10.1038/s41531-023-00482-4
Publikations ID PMID: 37015928
 


Clinical insights into small cell lung cancer: Tumor heterogeneity, diagnosis, therapy, and future directions.
Autoren Megyesfalvi Z, Gay CM, Popper H, Pirker R, Ostoros G, Heeke S, Lang C, Hoetzenecker K, Schwendenwein A, Boettiger K, Bunn PA, Renyi-Vamos F, Schelch K, Prosch H, Byers LA, Hirsch FR, Dome B
Erscheinungsdaten CA: a cancer journal for clinicians. 2023 Jun 17. doi: 10.3322/caac.21785
Publikations ID PMID: 37329269
 


Analysis of inflammatory markers and tau deposits in an autopsy series of nine patients with anti-IgLON5 disease.
Autoren Berger-Sieczkowski E, Endmayr V, Haider C, Ricken G, Jauk P, Macher S, Pirker W, Högl B, Heidbreder A, Schnider P, Bradley-Zechmeister E, Mariotto S, Koneczny I, Reinecke R, Kasprian G, Weber C, Bergmann M, Milenkovic I, Berger T, Gaig C, Sabater L, Graus F, Gelpi E, Höftberger R
Erscheinungsdaten Acta neuropathologica. 2023 Aug 30. doi: 10.1007/s00401-023-02625-6. pii: 10.1007/s00401-023-02625-6
Publikations ID PMID: 37646790