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Efficacy and safety of avelumab plus axitinib in elderly patients with advanced renal cell carcinoma: extended follow-up results from JAVELIN Renal 101.

Tomita Y, Motzer RJ, Choueiri TK, Rini BI, Miyake H, Uemura H, Albiges L, Fujii Y, Umeyama Y, Wang J, Mariani M, Schmidinger M

ESMO open. 2022 Apr 6. pii: S2059-7029(22)00066-7. doi: 10.1016/j.esmoop.2022.100450

PMID: 35397432

Mapping genomic loci implicates genes and synaptic biology in schizophrenia.

Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G, Zhang W, Adams M, Agartz I, Atkinson EG, Agerbo E, Al Eissa M, Albus M, Alexander M, Alizadeh BZ, Alptekin K, Als TD, Amin F, Arolt V, Arrojo M, Athanasiu L, Azevedo MH, Bacanu SA, Bass NJ, Begemann M, Belliveau RA, Bene J, Benyamin B, Bergen SE, Blasi G, Bobes J, Bonassi S, Braun A, Bressan RA, Bromet EJ, Bruggeman R, Buckley PF, Buckner RL, Bybjerg-Grauholm J, Cahn W, Cairns MJ, Calkins ME, Carr VJ, Castle D, Catts SV, Chambert KD, Chan RCK, Chaumette B, Cheng W, Cheung EFC, Chong SA, Cohen D, Consoli A, Cordeiro Q, Costas J, Curtis C, Davidson M, Davis KL, de Haan L, Degenhardt F, DeLisi LE, Demontis D, Dickerson F, Dikeos D, Dinan T, Djurovic S, Duan J, Ducci G, Dudbridge F, Eriksson JG, Fañanás L, Faraone SV, Fiorentino A, Forstner A, Frank J, Freimer NB, Fromer M, Frustaci A, Gadelha A, Genovese G, Gershon ES, Giannitelli M, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, González Peñas J, González-Pinto A, Gopal S, Gratten J, Green MF, Greenwood TA, Guillin O, Gülöksüz S, Gur RE, Gur RC, Gutiérrez B, Hahn E, Hakonarson H, Haroutunian V, Hartmann AM, Harvey C, Hayward C, Henskens FA, Herms S, Hoffmann P, Howrigan DP, Ikeda M, Iyegbe C, Joa I, Julià A, Kähler AK, Kam-Thong T, Kamatani Y, Karachanak-Yankova S, Kebir O, Keller MC, Kelly BJ, Khrunin A, Kim SW, Klovins J, Kondratiev N, Konte B, Kraft J, Kubo M, Kučinskas V, Kučinskiene ZA, Kusumawardhani A, Kuzelova-Ptackova H, Landi S, Lazzeroni LC, Lee PH, Legge SE, Lehrer DS, Lencer R, Lerer B, Li M, Lieberman J, Light GA, Limborska S, Liu CM, Lönnqvist J, Loughland CM, Lubinski J, Luykx JJ, Lynham A, Macek M, Mackinnon A, Magnusson PKE, Maher BS, Maier W, Malaspina D, Mallet J, Marder SR, Marsal S, Martin AR, Martorell L, Mattheisen M, McCarley RW, McDonald C, McGrath JJ, Medeiros H, Meier S, Melegh B, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mitjans M, Molden E, Molina E, Molto MD, Mondelli V, Moreno C, Morley CP, Muntané G, Murphy KC, Myin-Germeys I, Nenadić I, Nestadt G, Nikitina-Zake L, Noto C, Nuechterlein KH, O'Brien NL, O'Neill FA, Oh SY, Olincy A, Ota VK, Pantelis C, Papadimitriou GN, Parellada M, Paunio T, Pellegrino R, Periyasamy S, Perkins DO, Pfuhlmann B, Pietiläinen O, Pimm J, Porteous D, Powell J, Quattrone D, Quested D, Radant AD, Rampino A, Rapaport MH, Rautanen A, Reichenberg A, Roe C, Roffman JL, Roth J, Rothermundt M, Rutten BPF, Saker-Delye S, Salomaa V, Sanjuan J, Santoro ML, Savitz A, Schall U, Scott RJ, Seidman LJ, Sharp SI, Shi J, Siever LJ, Sigurdsson E, Sim K, Skarabis N, Slominsky P, So HC, Sobell JL, Söderman E, Stain HJ, Steen NE, Steixner-Kumar AA, Stögmann E, Stone WS, Straub RE, Streit F, Strengman E, Stroup TS, Subramaniam M, Sugar CA, Suvisaari J, Svrakic DM, Swerdlow NR, Szatkiewicz JP, Ta TMT, Takahashi A, Terao C, Thibaut F, Toncheva D, Tooney PA, Torretta S, Tosato S, Tura GB, Turetsky BI, Üçok A, Vaaler A, van Amelsvoort T, van Winkel R, Veijola J, Waddington J, Walter H, Waterreus A, Webb BT, Weiser M, Williams NM, Witt SH, Wormley BK, Wu JQ, Xu Z, Yolken R, Zai CC, Zhou W, Zhu F, Zimprich F, Atbaşoğlu EC, Ayub M, Benner C, Bertolino A, Black DW, Bray NJ, Breen G, Buccola NG, Byerley WF, Chen WJ, Cloninger CR, Crespo-Facorro B, Donohoe G, Freedman R, Galletly C, Gandal MJ, Gennarelli M, Hougaard DM, Hwu HG, Jablensky AV, McCarroll SA, Moran JL, Mors O, Mortensen PB, Müller-Myhsok B, Neil AL, Nordentoft M, Pato MT, Petryshen TL, Pirinen M, Pulver AE, Schulze TG, Silverman JM, Smoller JW, Stahl EA, Tsuang DW, Vilella E, Wang SH, Xu S, Adolfsson R, Arango C, Baune BT, Belangero SI, Børglum AD, Braff D, Bramon E, Buxbaum JD, Campion D, Cervilla JA, Cichon S, Collier DA, Corvin A, Curtis D, Forti MD, Domenici E, Ehrenreich H, Escott-Price V, Esko T, Fanous AH, Gareeva A, Gawlik M, Gejman PV, Gill M, Glatt SJ, Golimbet V, Hong KS, Hultman CM, Hyman SE, Iwata N, Jönsson EG, Kahn RS, Kennedy JL, Khusnutdinova E, Kirov G, Knowles JA, Krebs MO, Laurent-Levinson C, Lee J, Lencz T, Levinson DF, Li QS, Liu J, Malhotra AK, Malhotra D, McIntosh A, McQuillin A, Menezes PR, Morgan VA, Morris DW, Mowry BJ, Murray RM, Nimgaonkar V, Nöthen MM, Ophoff RA, Paciga SA, Palotie A, Pato CN, Qin S, Rietschel M, Riley BP, Rivera M, Rujescu D, Saka MC, Sanders AR, Schwab SG, Serretti A, Sham PC, Shi Y, St Clair D, Stefánsson H, Stefansson K, Tsuang MT, van Os J, Vawter MP, Weinberger DR, Werge T, Wildenauer DB, Yu X, Yue W, Holmans PA, Pocklington AJ, Roussos P, Vassos E, Verhage M, Visscher PM, Yang J, Posthuma D, Andreassen OA, Kendler KS, Owen MJ, Wray NR, Daly MJ, Huang H, Neale BM, Sullivan PF, Ripke S, Walters JTR, O'Donovan MC

Nature. 2022 Apr 8. doi: 10.1038/s41586-022-04434-5. pii: 10.1038/s41586-022-04434-5

PMID: 35396580

Situational factors shape moral judgements in the trolley dilemma in Eastern, Southern and Western countries in a culturally diverse sample.

Bago B, Kovacs M, Protzko J, Nagy T, Kekecs Z, Palfi B, Adamkovic M, Adamus S, Albalooshi S, Albayrak-Aydemir N, Alfian IN, Alper S, Alvarez-Solas S, Alves SG, Amaya S, Andresen PK, Anjum G, Ansari D, Arriaga P, Aruta JJBR, Arvanitis A, Babincak P, Barzykowski K, Bashour B, Baskin E, Batalha L, Batres C, Bavolar J, Bayrak F, Becker B, Becker M, Belaus A, Białek M, Bilancini E, Boller D, Boncinelli L, Boudesseul J, Brown BT, Buchanan EM, Butt MM, Calvillo DP, Carnes NC, Celniker JB, Chartier CR, Chopik WJ, Chotikavan P, Chuan-Peng H, Clancy RF, Çoker O, Correia RC, Adoric VC, Cubillas CP, Czoschke S, Daryani Y, de Grefte JAM, de Vries WC, Burak EGD, Dias C, Dixson BJW, Du X, Dumančić F, Dumbravă A, Dutra NB, Enachescu J, Esteban-Serna C, Eudave L, Evans TR, Feldman G, Felisberti FM, Fiedler S, Findor A, Fleischmann A, Foroni F, Francová R, Frank DA, Fu CHY, Gao S, Ghasemi O, Ghazi-Noori AR, Ghossainy ME, Giammusso I, Gill T, Gjoneska B, Gollwitzer M, Graton A, Grinberg M, Groyecka-Bernard A, Harris EA, Hartanto A, Hassan WANM, Hatami J, Heimark KR, Hidding JJJ, Hristova E, Hruška M, Hudson CA, Huskey R, Ikeda A, Inbar Y, Ingram GPD, Isler O, Isloi C, Iyer A, Jaeger B, Janssen SMJ, Jiménez-Leal W, Jokić B, Kačmár P, Kadreva V, Kaminski G, Karimi-Malekabadi F, Kasper ATA, Kendrick KM, Kennedy BJ, Kocalar HE, Kodapanakkal RI, Kowal M, Kruse E, Kučerová L, Kühberger A, Kuzminska AO, Lalot F, Lamm C, Lammers J, Lange EB, Lantian A, Lau IY, Lazarevic LB, Leliveld MC, Lenz JN, Levitan CA, Lewis SC, Li M, Li Y, Li H, Lima TJS, Lins S, Liuzza MT, Lopes P, Lu JG, Lynds T, Máčel M, Mackinnon SP, Maganti M, Magraw-Mickelson Z, Magson LF, Manley H, Marcu GM, Seršić DM, Matibag CJ, Mattiassi ADA, Mazidi M, McFall JP, McLatchie N, Mensink MC, Miketta L, Milfont TL, Mirisola A, Misiak M, Mitkidis P, Moeini-Jazani M, Monajem A, Moreau D, Musser ED, Narhetali E, Ochoa DP, Olsen J, Owsley NC, Özdoğru AA, Panning M, Papadatou-Pastou M, Parashar N, Pärnamets P, Paruzel-Czachura M, Parzuchowski M, Paterlini JV, Pavlacic JM, Peker M, Peters K, Piatnitckaia L, Pinto I, Policarpio MR, Pop-Jordanova N, Pratama AJ, Primbs MA, Pronizius E, Purić D, Puvia E, Qamari V, Qian K, Quiamzade A, Ráczová B, Reinero DA, Reips UD, Reyna C, Reynolds K, Ribeiro MFF, Röer JP, Ross RM, Roussos P, Ruiz-Dodobara F, Ruiz-Fernandez S, Rutjens BT, Rybus K, Samekin A, Santos AC, Say N, Schild C, Schmidt K, Ścigała KA, Sharifian M, Shi J, Shi Y, Sievers E, Sirota M, Slipenkyj M, Solak Ç, Sorokowska A, Sorokowski P, Söylemez S, Steffens NK, Stephen ID, Sternisko A, Stevens-Wilson L, Stewart SLK, Stieger S, Storage D, Strube J, Susa KJ, Szekely-Copîndean RD, Szostak NM, Takwin B, Tatachari S, Thomas AG, Tiede KE, Tiong LE, Tonković M, Trémolière B, Tunstead LV, Türkan BN, Twardawski M, Vadillo MA, Vally Z, Vaughn LA, Verschuere B, Vlašiček D, Voracek M, Vranka MA, Wang S, West SL, Whyte S, Wilton LS, Wlodarczyk A, Wu X, Xin F, Yadanar S, Yama H, Yamada Y, Yilmaz O, Yoon S, Young DM, Zakharov I, Zein RA, Zettler I, Žeželj IL, Zhang DC, Zhang J, Zheng X, Hoekstra R, Aczel B

Nature human behaviour. 2022 Apr 14. doi: 10.1038/s41562-022-01319-5. pii: 10.1038/s41562-022-01319-5

PMID: 35422529

Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region.

Jordahl KM, Shcherbina A, Kim AE, Su YR, Lin Y, Wang J, Qu C, Albanes D, Arndt V, Baurley JW, Berndt SI, Bien SA, Bishop DT, Bouras E, Brenner H, Buchanan DD, Budiarto A, Campbell PT, Carreras-Torres R, Casey G, Cenggoro TW, Chan AT, Conti DV, Dampier CH, Devall MA, Díez-Obrero V, Dimou N, Drew DA, Figueiredo JC, Gallinger S, Giles GG, Gruber SB, Gsur A, Gunter MJ, Hampel H, Harlid S, Harrison TA, Hidaka A, Hoffmeister M, Huyghe JR, Jenkins MA, Joshi AD, Keku TO, Larsson SC, Le Marchand L, Lewinger JP, Li L, Mahesworo B, Moreno V, Morrison JL, Murphy N, Nan H, Nassir R, Newcomb PA, Obón-Santacana M, Ogino S, Ose J, Pai RK, Palmer JR, Papadimitriou N, Pardamean B, Peoples AR, Pharoah PDP, Platz EA, Potter JD, Prentice RL, Rennert G, Ruiz-Narvaez E, Sakoda LC, Scacheri PC, Schmit SL, Schoen RE, Slattery ML, Stern MC, Tangen CM, Thibodeau SN, Thomas DC, Tian Y, Tsilidis KK, Ulrich CM, van Duijnhoven FJB, Van Guelpen B, Visvanathan K, Vodicka P, White E, Wolk A, Woods MO, Wu AH, Zemlianskaia N, Chang-Claude J, Gauderman WJ, Hsu L, Kundaje A, Peters U

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2022 Apr 19. pii: 694506. doi: 10.1158/1055-9965.EPI-21-1003

PMID: 35438744

(Wu Mei) Attenuates Acetic Acid-Induced Ulcerative Colitis by Regulating Inflammatory Cytokine, Reactive Oxygen Species, and Neuropeptide Levels in Model Rats.

Xu Z, Zhang X, Wang W, Zhang D, Ma Y, Zhang D, Chen M

Journal of medicinal food. doi: 10.1089/jmf.2021.K.0155

PMID: 35438553

Night work, chronotype and cortisol at awakening in female hospital employees.

Burek K, Rabstein S, Kantermann T, Vetter C, Rotter M, Wang-Sattler R, Lehnert M, Pallapies D, Jöckel KH, Brüning T, Behrens T

Scientific reports. 2022 Apr 20. doi: 10.1038/s41598-022-10054-w. pii: 10.1038/s41598-022-10054-w

PMID: 35443768

From the tyrosine hydroxylase hypothesis of Parkinson's disease to modern strategies: a short historical overview.

Rausch WD, Wang F, Radad K

Journal of neural transmission (Vienna, Austria : 1996). 2022 Apr 23. doi: 10.1007/s00702-022-02488-3. pii: 10.1007/s00702-022-02488-3

PMID: 35460433

Comparison of Implant Placement Accuracy in Healed and Fresh Extraction Sockets between Static and Dynamic Computer-Assisted Implant Surgery Navigation Systems: A Model-Based Evaluation.

Wang M, Rausch-Fan X, Zhan Y, Shen H, Liu F

Materials (Basel, Switzerland). 2022 Apr 11. pii: ma15082806. doi: 10.3390/ma15082806

PMID: 35454496

Impact of proton pump inhibitors on efficacy of antiplatelet strategies with ticagrelor or aspirin after percutaneous coronary intervention: Insights from the GLOBAL LEADERS trial.

Ono M, Onuma Y, Kawashima H, Hara H, Gao C, Wang R, O'Leary N, Benit E, Janssens L, Ferrario M, Żurakowski A, Dominici M, Huber K, Buszman P, Garg S, Wykrzykowska JJ, Piek JJ, Jüni P, Hamm C, Windecker S, Vranckx P, Deliargyris EN, Bhatt DL, Storey RF, Valgimigli M, Serruys PW

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 2022 May 2. doi: 10.1002/ccd.30217

PMID: 35500171

Rotating Night Shift Work and Healthy Aging After 24 Years of Follow-up in the Nurses' Health Study.

Shi H, Huang T, Schernhammer ES, Sun Q, Wang M

JAMA network open. 2022 May 2. pii: 2791848. doi: 10.1001/jamanetworkopen.2022.10450

PMID: 35507343

A dynamic single cell-based framework for digital twins to prioritize disease genes and drug targets.

Li X, Lee EJ, Lilja S, Loscalzo J, Schäfer S, Smelik M, Strobl MR, Sysoev O, Wang H, Zhang H, Zhao Y, Gawel DR, Bohle B, Benson M

Genome medicine. 2022 May 6. doi: 10.1186/s13073-022-01048-4. pii: 10.1186/s13073-022-01048-4

PMID: 35513850

Development of 'Core Outcome Sets' for Meningioma in Clinical Studies (The COSMIC Project): protocol for two systematic literature reviews, eDelphi surveys and online consensus meetings.

Millward CP, Armstrong TS, Barrington H, Bell S, Brodbelt AR, Bulbeck H, Crofton A, Dirven L, Georgious T, Grundy PL, Islim AI, Javadpour M, Keshwara SM, Koszdin SD, Marson AG, McDermott MW, Meling TR, Oliver K, Plaha P, Preusser M, Santarius T, Srikandarajah N, Taphoorn MJB, Turner C, Watts C, Weller M, Williamson PR, Zadeh G, Zamanipoor Najafabadi AH, Jenkinson MD

BMJ open. 2022 May 9. pii: bmjopen-2021-057384. doi: 10.1136/bmjopen-2021-057384

PMID: 35534067

Infants and Newborns with Atypical Teratoid Rhabdoid Tumors (ATRT) and Extracranial Malignant Rhabdoid Tumors (eMRT) in the EU-RHAB Registry: A Unique and Challenging Population.

Nemes K, Johann PD, Steinbügl M, Gruhle M, Bens S, Kachanov D, Teleshova M, Hauser P, Simon T, Tippelt S, Eberl W, Chada M, Lopez VS, Grigull L, Hernáiz-Driever P, Eyrich M, Pears J, Milde T, Reinhard H, Leipold A, van de Wetering M, Gil-da-Costa MJ, Ebetsberger-Dachs G, Kerl K, Lemmer A, Boztug H, Furtwängler R, Kordes U, Vokuhl C, Hasselblatt M, Bison B, Kröncke T, Melchior P, Timmermann B, Gerss J, Siebert R, Frühwald MC

Cancers. 2022 Apr 27. pii: cancers14092185. doi: 10.3390/cancers14092185

PMID: 35565313

Adjunctive Left Atrial Posterior Wall Isolation in Treating Atrial Fibrillation: Insight From a Large Secondary Analysis.

Jiang X, Liao J, Ling Z, Meyer C, Sommer P, Futyma P, Martinek M, Schratter A, Acou WJ, Wang J, Zhu L, Kiuchi MG, Pürerfellner H, Schmidt B, Chun JKR, Yin Y, Chen S

JACC. Clinical electrophysiology. 2022 Mar 30. pii: S2405-500X(22)00134-7. doi: 10.1016/j.jacep.2022.02.001

PMID: 35589173

KRAS alterations in colorectal liver metastases: shifting to exon, codon, and point mutations.

Olthof PB, Buettner S, Andreatos N, Wang J, Løes IM, Wagner D, Sasaki K, Macher-Beer A, Kamphues C, Pozios I, Seeliger H, Morioka D, Imai K, Kaczirek K, Pawlik TM, Poultsides G, Burkhart R, Endo I, Baba H, Kornprat P, Aucejo FN, Lønning PE, Beyer K, Weiss MJ, Wolfgang CL, Kreis ME, Margonis GA

The British journal of surgery. 2022 May 20. pii: 6589849. doi: 10.1093/bjs/znac147

PMID: 35595182

Fast CBCT Reconstruction using Convolutional Neural Networks for Arbitrary Robotic C-arm Orbits.

Russ T, Ma YQ, Golla AK, Bauer DF, Reynolds T, Tönnes C, Hatamikia S, Schad LR, Zöllner FG, Gang GJ, Wang W, Stayman JW

Proceedings of SPIE--the International Society for Optical Engineering. 2022 Apr 4. doi: 10.1117/12.2612935. pmc: PMC9119361. mid: NIHMS1806728

PMID: 35601023

WAO-ARIA consensus on chronic cough - Part III: Management strategies in primary and cough-specialty care. .

Rouadi PW, Idriss SA, Bousquet J, Laidlaw TM, Azar CR, Al-Ahmad MS, Yañez A, Al-Nesf MAY, Nsouli TM, Bahna SL, Abou-Jaoude E, Zaitoun FH, Hadi UM, Hellings PW, Scadding GK, Smith PK, Morais-Almeida M, Maximiliano Gómez R, Gonzalez Diaz SN, Klimek L, Juvelekian GS, Riachy MA, Canonica GW, Peden D, Wong GWK, Sublett J, Bernstein JA, Wang L, Tanno LK, Chikhladze M, Levin M, Chang YS, Martin BL, Caraballo L, Custovic A, Ortego-Martell JA, Lesslar OJL, Jensen-Jarolim E, Ebisawa M, Fiocchi A, Ansotegui IJ

The World Allergy Organization journal. 2022 May 14. doi: 10.1016/j.waojou.2022.100649. pii: S1939-4551(22)00025-4. pmc: PMC9117692

PMID: 35600836

Cell-Free RNA as a Novel Biomarker for Response to Therapy in Head & Neck Cancer.

Tosevska A, Morselli M, Basak SK, Avila L, Mehta P, Wang MB, Srivatsan ES, Pellegrini M

Frontiers in oncology. 2022 May 6. doi: 10.3389/fonc.2022.869108. pmc: PMC9121879

PMID: 35600369

Isolation of a Human Betaretrovirus from Patients with Primary Biliary Cholangitis.

Goubran M, Wang W, Indik S, Faschinger A, Wasilenko ST, Bintner J, Carpenter EJ, Zhang G, Nuin P, Macintyre G, Wong GK, Mason AL

Viruses. 2022 Apr 24. pii: v14050886. doi: 10.3390/v14050886

PMID: 35632628

Network Approaches for Charting the Transcriptomic and Epigenetic Landscape of the Developmental Origins of Health and Disease.

Lombardo SD, Wangsaputra IF, Menche J, Stevens A