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Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R. |
Mirkina I, Hadzijusufovic E, Krepler C, Mikula M, Mechtcheriakova D, Strommer S, Stella A, Jensen-Jarolim E, Höller C, Wacheck V, Pehamberger H, Valent P |
PloS one. 2014 Jan 29. doi: 10.1371/journal.pone.0084417. pii: PONE-D-13-39207. pmc: PMC3906015 |
PMID: 24489649 |
MET expression in melanoma correlates with a lymphangiogenic phenotype. |
Swoboda A, Schanab O, Tauber S, Bilban M, Berger W, Petzelbauer P, Mikula M |
Human molecular genetics. 2012 May 7. pii: dds171. doi: 10.1093/hmg/dds171 |
PMID: 22570180 |
Human amniotic fluid stem cells as a model for functional studies of genes involved in human genetic diseases or oncogenesis. |
Rosner M, Dolznig H, Schipany K, Mikula M, Brandau O, Hengstschläger M |
Oncotarget. 2011 Oct 24. pii: 328. pmc: PMC3248217 |
PMID: 21926447 |
Identification of genetic disparity between primary and metastatic melanoma in human patients. |
Swoboda A, Rasin-Streden D, Schanab O, Okamoto I, Pehamberger H, Petzelbauer P, Mikula M |
Genes, chromosomes & cancer. 2011 May 16. doi: 10.1002/gcc.20890 |
PMID: 21584902 |
Expression of human endogenous retrovirus K is stimulated by ultraviolet radiation in melanoma. |
Schanab O, Humer J, Gleiss A, Mikula M, Sturlan S, Grunt S, Okamoto I, Muster T, Pehamberger H, Waltenberger A |
Pigment cell & melanoma research. 2011 Jun 6. doi: 10.1111/j.1755-148X.2011.00860.x |
PMID: 21501418 |
Crucial function of histone deacetylase 1 for differentiation of teratomas in mice and humans. |
Lagger S, Meunier D, Mikula M, Brunmeir R, Schlederer M, Artaker M, Pusch O, Egger G, Hagelkruys A, Mikulits W, Weitzer G, Muellner EW, Susani M, Kenner L, Seiser C |
The EMBO journal. 2010 Oct 22. pii: emboj2010264. doi: 10.1038/emboj.2010.264. pmc: PMC3020644 |
PMID: 20967026 |
Nuclear beta-catenin induces an early liver progenitor phenotype in hepatocellular carcinoma and promotes tumor recurrence. |
Zulehner G, Mikula M, Schneller D, van Zijl F, Huber H, Sieghart W, Grasl-Kraupp B, Waldhör T, Peck-Radosavljevic M, Beug H, Mikulits W |
The American journal of pathology. 2009 Dec 11. pii: S0002-9440(10)60360-4. doi: 10.2353/ajpath.2010.090300. pmc: PMC2797905. mid: UKMS32685 |
PMID: 20008139 |
3,3',4,4',5,5'-hexahydroxystilbene impairs melanoma progression in a metastatic mouse model. |
Paulitschke V, Schicher N, Szekeres T, Jäger W, Elbling L, Riemer AB, Scheiner O, Trimurtulu G, Venkateswarlu S, Mikula M, Swoboda A, Fiebiger E, Gerner C, Pehamberger H, Kunstfeld R |
The Journal of investigative dermatology. 2009 Dec 3. pii: jid2009376. doi: 10.1038/jid.2009.376 |
PMID: 19956188 |
ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression. |
Lahsnig C, Mikula M, Petz M, Zulehner G, Schneller D, van Zijl F, Huber H, Csiszar A, Beug H, Mikulits W |
Oncogene. 2008 Nov 17. pii: onc2008418. doi: 10.1038/onc.2008.418. pmc: PMC2900603. mid: UKMS31284 |
PMID: 19015638 |
Down-regulation of Sprouty2 in non-small cell lung cancer contributes to tumor malignancy via extracellular signal-regulated kinase pathway-dependent and -independent mechanisms. |
Sutterlüty H, Mayer CE, Setinek U, Attems J, Ovtcharov S, Mikula M, Mikulits W, Micksche M, Berger W |
Molecular cancer research : MCR. 2007 May 18. pii: 5/5/509. doi: 10.1158/1541-7786.MCR-06-0273 |
PMID: 17510316 |
The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity. |
Aigner K, Dampier B, Descovich L, Mikula M, Sultan A, Schreiber M, Mikulits W, Brabletz T, Strand D, Obrist P, Sommergruber W, Schweifer N, Wernitznig A, Beug H, Foisner R, Eger A |
Oncogene. 2007 May 7. pii: 1210508. doi: 10.1038/sj.onc.1210508. pmc: PMC2899859. mid: UKMS31286 |
PMID: 17486063 |
The transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progression. |
Aigner K, Descovich L, Mikula M, Sultan A, Dampier B, Bonné S, van Roy F, Mikulits W, Schreiber M, Brabletz T, Sommergruber W, Schweifer N, Wernitznig A, Beug H, Foisner R, Eger A |
FEBS letters. 2007 Mar 21. pii: S0014-5793(07)00286-4. doi: 10.1016/j.febslet.2007.03.026. pmc: PMC2938730. mid: UKMS31288 |
PMID: 17391671 |
PDGF essentially links TGF-beta signaling to nuclear beta-catenin accumulation in hepatocellular carcinoma progression. |
Fischer AN, Fuchs E, Mikula M, Huber H, Beug H, Mikulits W |
Oncogene. 2006 Nov 20. pii: 1210121. doi: 10.1038/sj.onc.1210121 |
PMID: 17130832 |
Activated hepatic stellate cells induce tumor progression of neoplastic hepatocytes in a TGF-beta dependent fashion. |
Mikula M, Proell V, Fischer AN, Mikulits W |
Journal of cellular physiology. 2006 Sep 4. doi: 10.1002/jcp.20772. pmc: PMC2900580. mid: UKMS31283 |
PMID: 16883581 |
Impact of constitutive IGF1/IGF2 stimulation on the transcriptional program of human breast cancer cells. |
Pacher M, Seewald MJ, Mikula M, Oehler S, Mogg M, Vinatzer U, Eger A, Schweifer N, Varecka R, Sommergruber W, Mikulits W, Schreiber M |
Carcinogenesis. 2006 Jun 14. pii: bgl091. doi: 10.1093/carcin/bgl091 |
PMID: 16774935 |
A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes. |
Gotzmann J, Fischer AN, Zojer M, Mikula M, Proell V, Huber H, Jechlinger M, Waerner T, Weith A, Beug H, Mikulits W |
Oncogene. 2006 May 25. pii: 1209083. doi: 10.1038/sj.onc.1209083 |
PMID: 16607286 |
Telomerase- and alternative telomere lengthening-independent telomere stabilization in a metastasis-derived human non-small cell lung cancer cell line: effect of ectopic hTERT. |
Brachner A, Sasgary S, Pirker C, Rodgarkia C, Mikula M, Mikulits W, Bergmeister H, Setinek U, Wieser M, Chin SF, Caldas C, Micksche M, Cerni C, Berger W |
Cancer research. 2006 Apr 4. pii: 66/7/3584. doi: 10.1158/0008-5472.CAN-05-2839 |
PMID: 16585183 |
The plasticity of p19 ARF null hepatic stellate cells and the dynamics of activation. |
Proell V, Mikula M, Fuchs E, Mikulits W |
Biochimica et biophysica acta. 2005 Jan 21. pii: S0167-4889(04)00353-2. doi: 10.1016/j.bbamcr.2004.12.009 |
PMID: 15878400 |
Integration of Ras subeffector signaling in TGF-beta mediated late stage hepatocarcinogenesis. |
Fischer AN, Herrera B, Mikula M, Proell V, Fuchs E, Gotzmann J, Schulte-Hermann R, Beug H, Mikulits W |
Carcinogenesis. 2005 Feb 10. pii: bgi043. doi: 10.1093/carcin/bgi043 |
PMID: 15705598 |
beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition. |
Eger A, Stockinger A, Park J, Langkopf E, Mikula M, Gotzmann J, Mikulits W, Beug H, Foisner R |
Oncogene. 2004 Apr 8. doi: 10.1038/sj.onc.1207416. pii: 1207416 |
PMID: 14755243 |
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