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Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial. |
Martin M, Holmes FA, Ejlertsen B, Delaloge S, Moy B, Iwata H, von Minckwitz G, Chia SKL, Mansi J, Barrios CH, Gnant M, Tomašević Z, Denduluri N, Šeparović R, Gokmen E, Bashford A, Ruiz Borrego M, Kim SB, Jakobsen EH, Ciceniene A, Inoue K, Overkamp F, Heijns JB, Armstrong AC, Link JS, Joy AA, Bryce R, Wong A, Moran S, Yao B, Xu F, Auerbach A, Buyse M, Chan A |
The Lancet. Oncology. 2017 Nov 13. pii: S1470-2045(17)30717-9. doi: 10.1016/S1470-2045(17)30717-9 |
PMID: 29146401 |
Recombinant single-chain factor VIII in severe hemophilia: Long-term safety and efficacy in previously treated patients in the AFFINITY extension study. |
Mahlangu J, Abdul Karim F, Stasyshyn O, Korczowski B, Salazar B, Lucas S, Suen A, Goldstein B, Chung T, Pabinger I |
Research and practice in thrombosis and haemostasis. 2022 Feb 14. doi: 10.1002/rth2.12665. pii: RTH212665. pmc: PMC8844480 |
PMID: 35224416 |
Identification of six new susceptibility loci for invasive epithelial ovarian cancer. |
Kuchenbaecker KB, Ramus SJ, Tyrer J, Lee A, Shen HC, Beesley J, Lawrenson K, McGuffog L, Healey S, Lee JM, Spindler TJ, Lin YG, Pejovic T, Bean Y, Li Q, Coetzee S, Hazelett D, Miron A, Southey M, Terry MB, Goldgar DE, Buys SS, Janavicius R, Dorfling CM, van Rensburg EJ, Neuhausen SL, Ding YC, Hansen TV, Jønson L, Gerdes AM, Ejlertsen B, Barrowdale D, Dennis J, Benitez J, Osorio A, Garcia MJ, Komenaka I, Weitzel JN, Ganschow P, Peterlongo P, Bernard L, Viel A, Bonanni B, Peissel B, Manoukian S, Radice P, Papi L, Ottini L, Fostira F, Konstantopoulou I, Garber J, Frost D, Perkins J, Platte R, Ellis S, Godwin AK, Schmutzler RK, Meindl A, Engel C, Sutter C, Sinilnikova OM, Damiola F, Mazoyer S, Stoppa-Lyonnet D, Claes K, De Leeneer K, Kirk J, Rodriguez GC, Piedmonte M, O'Malley DM, de la Hoya M, Caldes T, Aittomäki K, Nevanlinna H, Collée JM, Rookus MA, Oosterwijk JC, Tihomirova L, Tung N, Hamann U, Isaccs C, Tischkowitz M, Imyanitov EN, Caligo MA, Campbell IG, Hogervorst FB, Olah E, Diez O, Blanco I, Brunet J, Lazaro C, Pujana MA, Jakubowska A, Gronwald J, Lubinski J, Sukiennicki G, Barkardottir RB, Plante M, Simard J, Soucy P, Montagna M, Tognazzo S, Teixeira MR, Pankratz VS, Wang X, Lindor N, Szabo CI, Kauff N, Vijai J, Aghajanian CA, Pfeiler G, Berger A, Singer CF, Tea MK, Phelan CM, Greene MH, Mai PL, Rennert G, Mulligan AM, Tchatchou S, Andrulis IL, Glendon G, Toland AE, Jensen UB, Kruse TA, Thomassen M, Bojesen A, Zidan J, Friedman E, Laitman Y, Soller M, Liljegren A, Arver B, Einbeigi Z, Stenmark-Askmalm M, Olopade OI, Nussbaum RL, Rebbeck TR, Nathanson KL, Domchek SM, Lu KH, Karlan BY, Walsh C, Lester J, Hein A, Ekici AB, Beckmann MW, Fasching PA, Lambrechts D, Van Nieuwenhuysen E, Vergote I, Lambrechts S, Dicks E, Doherty JA, Wicklund KG, Rossing MA, Rudolph A, Chang-Claude J, Wang-Gohrke S, Eilber U, Moysich KB, Odunsi K, Sucheston L, Lele S, Wilkens LR, Goodman MT, Thompson PJ, Shvetsov YB, Runnebaum IB, Dürst M, Hillemanns P, Dörk T, Antonenkova N, Bogdanova N, Leminen A, Pelttari LM, Butzow R, Modugno F, Kelley JL, Edwards RP, Ness RB, du Bois A, Heitz F, Schwaab I, Harter P, Matsuo K, Hosono S, Orsulic S, Jensen A, Kjaer SK, Hogdall E, Hasmad HN, Azmi MA, Teo SH, Woo YL, Fridley BL, Goode EL, Cunningham JM, Vierkant RA, Bruinsma F, Giles GG, Liang D, Hildebrandt MA, Wu X, Levine DA, Bisogna M, Berchuck A, Iversen ES, Schildkraut JM, Concannon P, Weber RP, Cramer DW, Terry KL, Poole EM, Tworoger SS, Bandera EV, Orlow I, Olson SH, Krakstad C, Salvesen HB, Tangen IL, Bjorge L, van Altena AM, Aben KK, Kiemeney LA, Massuger LF, Kellar M, Brooks-Wilson A, Kelemen LE, Cook LS, Le ND, Cybulski C, Yang H, Lissowska J, Brinton LA, Wentzensen N, Hogdall C, Lundvall L, Nedergaard L, Baker H, Song H, Eccles D, McNeish I, Paul J, Carty K, Siddiqui N, Glasspool R, Whittemore AS, Rothstein JH, McGuire V, Sieh W, Ji BT, Zheng W, Shu XO, Gao YT, Rosen B, Risch HA, McLaughlin JR, Narod SA, Monteiro AN, Chen A, Lin HY, Permuth-Wey J, Sellers TA, Tsai YY, Chen Z, Ziogas A, Anton-Culver H, Gentry-Maharaj A, Menon U, Harrington P, Lee AW, Wu AH, Pearce CL, Coetzee G, Pike MC, Dansonka-Mieszkowska A, Timorek A, Rzepecka IK, Kupryjanczyk J, Freedman M, Noushmehr H, Easton DF, Offit K, Couch FJ, Gayther S, Pharoah PP, Antoniou AC, Chenevix-Trench G |
Nature genetics. 2015 Jan 12. pii: ng.3185. doi: 10.1038/ng.3185. pmc: PMC4445140. mid: NIHMS647338 |
PMID: 25581431 |
Modulating the tumor microenvironment with RNA interference as a cancer treatment strategy. |
Zins K, Sioud M, Aharinejad S, Lucas T, Abraham D |
Methods in molecular biology (Clifton, N.J.). 2014 Oct 16. doi: 10.1007/978-1-4939-1538-5_9 |
PMID: 25319650 |
Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity. |
Zins K, Gunawardhana S, Lucas T, Abraham D, Aharinejad S |
Journal of translational medicine. 2013 Nov 27. pii: 1479-5876-11-295. doi: 10.1186/1479-5876-11-295. pmc: PMC4222769 |
PMID: 24279335 |
A Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in mice. |
Zins K, Lucas T, Reichl P, Abraham D, Aharinejad S |
PloS one. 2013 Sep 11. doi: 10.1371/journal.pone.0074924. pii: PONE-D-13-15547. pmc: PMC3770583 |
PMID: 24040362 |
Inhibition of stromal PlGF suppresses the growth of prostate cancer xenografts. |
Zins K, Thomas A, Lucas T, Sioud M, Aharinejad S, Abraham D |
International journal of molecular sciences. 2013 Sep 3. pii: ijms140917958. doi: 10.3390/ijms140917958. pmc: PMC3794762 |
PMID: 24005860 |
CXCL9 induces chemotaxis, chemorepulsion and endothelial barrier disruption through CXCR3-mediated activation of melanoma cells. |
Amatschek S, Lucas R, Eger A, Pflueger M, Hundsberger H, Knoll C, Grosse-Kracht S, Schuett W, Koszik F, Maurer D, Wiesner C |
British journal of cancer. 2010 Dec 21. pii: 6606056. doi: 10.1038/sj.bjc.6606056. pmc: PMC3049560 |
PMID: 21179030 |
Stromal cell-derived CSF-1 blockade prolongs xenograft survival of CSF-1-negative neuroblastoma. |
Abraham D, Zins K, Sioud M, Lucas T, Schäfer R, Stanley ER, Aharinejad S |
International journal of cancer. Journal international du cancer. 2010 Jan 25. doi: 10.1002/ijc.24859. pmc: PMC3222589. mid: NIHMS337851 |
PMID: 19711348 |
Adenoviral-mediated endothelial precursor cell delivery of soluble CD115 suppresses human prostate cancer xenograft growth in mice. |
Lucas T, Abraham D, Untergasser G, Zins K, Hofer E, Gunsilius E, Aharinejad S |
Stem cells (Dayton, Ohio). 2009 Sep 16. doi: 10.1002/stem.145. pmc: PMC2879317. mid: UKMS30450 |
PMID: 19522014 |
Targeting stromal-cancer cell interactions with siRNAs. |
Aharinejad S, Sioud M, Lucas T, Abraham D |
Methods in molecular biology (Clifton, N.J.). 2009 Mar 23. doi: 10.1007/978-1-60327-547-7_12 |
PMID: 19301651 |
Modulation of tumor associated macrophages in solid tumors. |
Lucas T, Abraham D, Aharinejad S |
Frontiers in bioscience : a journal and virtual library. 2008 May 1. pii: 3101 |
PMID: 18508607 |
Host CD147 blockade by small interfering RNAs suppresses growth of human colon cancer xenografts. |
Abraham D, Zins K, Sioud M, Lucas T, Aharinejad S |
Frontiers in bioscience : a journal and virtual library. 2008 May 1. pii: 3100 |
PMID: 18508606 |
Target validation using RNA interference in solid tumors. |
Aharinejad S, Sioud M, Lucas T, Abraham D |
Methods in molecular biology (Clifton, N.J.). 2006 Dec 18. pii: 1-59745-208-4:227. doi: 10.1385/1-59745-208-4:227 |
PMID: 17172715 |
Vinflunine-gemcitabine versus vinflunine-carboplatin as first-line chemotherapy in cisplatin-unfit patients with advanced urothelial carcinoma: results of an international randomized phase II trial (JASINT1). |
De Santis M, Wiechno PJ, Bellmunt J, Lucas C, Su WC, Albiges L, Lin CC, Senkus-Konefka E, Flechon A, Mourey L, Necchi A, Loidl WC, Retz MM, Vaissière N, Culine S |
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 2015 Dec 16. pii: mdv609. doi: 10.1093/annonc/mdv609 |
PMID: 26673352 |
Autoimmune Bullous Skin Disorders with Immune Checkpoint Inhibitors Targeting PD-1 and PD-L1. |
Naidoo J, Schindler K, Querfeld C, Busam KJ, Cunningham J, Page DB, Postow MA, Weinstein A, Skripnik Lucas A, Ciccolini KT, Quigley EA, Lesokhin AM, Paik PK, Chaft JE, Segal NH, D'Angelo SP, Dickson MA, Wolchok JD, Lacouture ME |
Cancer immunology research. 2016 Feb 29. pii: 2326-6066.CIR-15-0123. doi: 10.1158/2326-6066.CIR-15-0123 |
PMID: 26928461 |
PlGF and VEGF-A Regulate Growth of High-Risk MYCN-Single Copy Neuroblastoma Xenografts via Different Mechanisms. |
Zins K, Kovatchki D, Lucas T, Abraham D |
International journal of molecular sciences. 2016 Sep 23. pii: ijms17101613. doi: 10.3390/ijms17101613 |
PMID: 27669225 |
812PDMATURE SURVIVAL (OS) DATA OF A RANDOMISED INTERNATIONAL PHASE II TRIAL (JASINT1): VINFLUNINE (VFL)-GEMCITABINE (GEM) VS. VFL-CBDCA IN CDDP-UNFIT PATIENTS (PTS) WITH ADVANCED UROTHELIAL CARCINOMA (UC). |
De Santis M, Wiechno PJ, Lucas C, Lin C, Su W, Bellmunt J, Legrand K, Fougeray R, Culine S |
Annals of oncology : official journal of the European Society for Medical Oncology. 2017 Feb 7. pii: 2241576. doi: 10.1093/annonc/mdu337.5 |
PMID: 28171465 |
Restoration of Epithelial Sodium Channel Function by Synthetic Peptides in Pseudohypoaldosteronism Type 1B Mutants. |
Willam A, Aufy M, Tzotzos S, Evanzin H, Chytracek S, Geppert S, Fischer B, Fischer H, Pietschmann H, Czikora I, Lucas R, Lemmens-Gruber R, Shabbir W |
Frontiers in pharmacology. 2017 Feb 24. doi: 10.3389/fphar.2017.00085. pmc: PMC5323398 |
PMID: 28286482 |
TNF Lectin-Like Domain Restores Epithelial Sodium Channel Function in Frameshift Mutants Associated with Pseudohypoaldosteronism Type 1B. |
Willam A, Aufy M, Tzotzos S, El-Malazi D, Poser F, Wagner A, Unterköfler B, Gurmani D, Martan D, Iqbal SM, Fischer B, Fischer H, Pietschmann H, Czikora I, Lucas R, Lemmens-Gruber R, Shabbir W |
Frontiers in immunology. 2017 May 29. doi: 10.3389/fimmu.2017.00601. pmc: PMC5447021 |
PMID: 28611771 |
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