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| Collaborative Efforts Driving Progress in Pediatric Acute Myeloid Leukemia. |
| Zwaan CM, Kolb EA, Reinhardt D, Abrahamsson J, Adachi S, Aplenc R, De Bont ES, De Moerloose B, Dworzak M, Gibson BE, Hasle H, Leverger G, Locatelli F, Ragu C, Ribeiro RC, Rizzari C, Rubnitz JE, Smith OP, Sung L, Tomizawa D, van den Heuvel-Eibrink MM, Creutzig U, Kaspers GJ |
| Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2015 Aug 24. pii: JCO.2015.62.8289. doi: 10.1200/JCO.2015.62.8289 |
| PMID: 26304895 |
| Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study. |
| Inaba H, Zhou Y, Abla O, Adachi S, Auvrignon A, Beverloo HB, de Bont E, Chang TT, Creutzig U, Dworzak M, Elitzur S, Fynn A, Forestier E, Hasle H, Liang DC, Lee V, Locatelli F, Masetti R, De Moerloose B, Reinhardt D, Rodriguez L, Van Roy N, Shen S, Taga T, Tomizawa D, Yeoh AE, Zimmermann M, Raimondi SC |
| Blood. 2015 Jul 27. pii: blood-2015-02-629204. doi: 10.1182/blood-2015-02-629204 |
| PMID: 26215111 |
| Criteria for evaluating response and outcome in clinical trials for children with juvenile myelomonocytic leukemia. |
| Niemeyer CM, Loh ML, Cseh A, Cooper T, Dvorak CC, Chan R, Xicoy B, Germing U, Kojima S, Manabe A, Dworzak M, De Moerloose B, Starý J, Smith OP, Masetti R, Catala A, Bergstraesser E, Ussowicz M, Fabri O, Baruchel A, Cavé H, Zwaan M, Locatelli F, Hasle H, van den Heuvel-Eibrink MM, Flotho C, Yoshimi A |
| Haematologica. 2015 Jan 1. pii: haematol.2014.109892. doi: 10.3324/haematol.2014.109892. pmc: PMC4281308 |
| PMID: 25552679 |
| RASA4 undergoes DNA hypermethylation in resistant juvenile myelomonocytic leukemia. |
| Poetsch AR, Lipka DB, Witte T, Claus R, Nöllke P, Zucknick M, Olk-Batz C, Fluhr S, Dworzak M, De Moerloose B, Starý J, Zecca M, Hasle H, Schmugge M, van den Heuvel-Eibrink MM, Locatelli F, Niemeyer CM, Flotho C, Plass C |
| Epigenetics. 2014 Jul 31. pii: 29941. doi: 10.4161/epi.29941. pmc: PMC4169017 |
| PMID: 25147919 |
| T-cell receptor Vβ skewing frequently occurs in refractory cytopenia of childhood and is associated with an expansion of effector cytotoxic T cells: a prospective study by EWOG-MDS. |
| Aalbers AM, van den Heuvel-Eibrink MM, Baumann I, Beverloo HB, Driessen GJ, Dworzak M, Fischer A, Göhring G, Hasle H, Locatelli F, De Moerloose B, Noellke P, Schmugge M, Stary J, Yoshimi A, Zecca M, Zwaan CM, van Dongen JJ, Pieters R, Niemeyer CM, van der Velden VH, Langerak AW |
| Blood cancer journal. 2014 May 2. pii: bcj201428. doi: 10.1038/bcj.2014.28. pmc: PMC4042298 |
| PMID: 24786393 |
| The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood: a prospective study by EWOG-MDS. |
| Aalbers AM, van der Velden VH, Yoshimi A, Fischer A, Noellke P, Zwaan CM, Baumann I, Beverloo HB, Dworzak M, Hasle H, Locatelli F, De Moerloose B, Göhring G, Schmugge M, Stary J, Zecca M, Langerak AW, van Dongen JJ, Pieters R, Niemeyer CM, van den Heuvel-Eibrink MM |
| Leukemia. 2013 Jun 28. pii: leu2013195. doi: 10.1038/leu.2013.195 |
| PMID: 23807769 |
| Clinical Impact of Additional Cytogenetic Aberrations, cKIT and RAS Mutations, and Treatment Elements in Pediatric t(8;21)-AML: Results From an International Retrospective Study by the International Berlin-Frankfurt-Münster Study Group. |
| Klein K, Kaspers G, Harrison CJ, Beverloo HB, Reedijk A, Bongers M, Cloos J, Pession A, Reinhardt D, Zimmerman M, Creutzig U, Dworzak M, Alonzo T, Johnston D, Hirsch B, Zapotocky M, De Moerloose B, Fynn A, Lee V, Taga T, Tawa A, Auvrignon A, Zeller B, Forestier E, Salgado C, Balwierz W, Popa A, Rubnitz J, Raimondi S, Gibson B |
| Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2015 Nov 16. pii: JCO.2015.61.1947. doi: 10.1200/JCO.2015.61.1947 |
| PMID: 26573082 |
| Additional cytogenetic abnormalities and variant t(9;22) at the diagnosis of childhood chronic myeloid leukemia: The experience of the International Registry for Chronic Myeloid Leukemia in Children and Adolescents. |
| Millot F, Dupraz C, Guilhot J, Suttorp M, Brizard F, Leblanc T, Güneş AM, Sedlacek P, De Bont E, Li CK, Kalwak K, Lausen B, Culic S, Dworzak M, Kaiserova E, De Moerloose B, Roula F, Biondi A, Baruchel A, Guilhot F |
| Cancer. 2017 May 12. doi: 10.1002/cncr.30767 |
| PMID: 28497898 |
| Recurrently affected genes in juvenile myelomonocytic leukaemia. |
| Obenauer JC, Kavelaars FG, Sanders MA, de Vries ACH, de Haas V, Beverloo HB, De Moerloose B, Lammens T, Dworzak M, Hoogenboezem RM, Valk PJM, Touw IP, van den Heuvel-Eibrink MM |
| British journal of haematology. 2017 May 9. doi: 10.1111/bjh.14737 |
| PMID: 28485469 |
| Characteristics and outcome in patients with central nervous system involvement treated in European pediatric acute myeloid leukemia study groups. |
| Creutzig U, Dworzak MN, Zimmermann M, Reinhardt D, Sramkova L, Bourquin JP, Hasle H, Abrahamsson J, Kaspers G, van den Heuvel MM, Reedijk AMJ, De Moerloose B, Locatelli F, Masetti R |
| Pediatric blood & cancer. 2017 Jun 9. doi: 10.1002/pbc.26664 |
| PMID: 28598536 |
| Prognostic discrimination based on the EUTOS long term survival score within the international registry for chronic myeloid leukemia in children and adolescents. |
| Millot F, Guilhot J, Suttorp M, Maral Güneş A, Sedlacek P, De Bont E, Li CK, Kalwak K, Lausen B, Culic S, Dworzark M, Kaiserova E, De Moerloose B, Roula F, Biondi A, Baruchel A |
| Haematologica. 2017 Aug 24. pii: haematol.2017.170035. doi: 10.3324/haematol.2017.170035 |
| PMID: 28838993 |
| RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia. |
| Lipka DB, Witte T, Toth R, Yang J, Wiesenfarth M, Nöllke P, Fischer A, Brocks D, Gu Z, Park J, Strahm B, Wlodarski M, Yoshimi A, Claus R, Lübbert M, Busch H, Boerries M, Hartmann M, Schönung M, Kilik U, Langstein J, Wierzbinska JA, Pabst C, Garg S, Catalá A, De Moerloose B, Dworzak M, Hasle H, Locatelli F, Masetti R, Schmugge M, Smith O, Stary J, Ussowicz M, van den Heuvel-Eibrink MM, Assenov Y, Schlesner M, Niemeyer C, Flotho C, Plass C |
| Nature communications. 2017 Dec 19. doi: 10.1038/s41467-017-02177-w. pii: 10.1038/s41467-017-02177-w |
| PMID: 29259247 |
| Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia. |
| Maude SL, Laetsch TW, Buechner J, Rives S, Boyer M, Bittencourt H, Bader P, Verneris MR, Stefanski HE, Myers GD, Qayed M, De Moerloose B, Hiramatsu H, Schlis K, Davis KL, Martin PL, Nemecek ER, Yanik GA, Peters C, Baruchel A, Boissel N, Mechinaud F, Balduzzi A, Krueger J, June CH, Levine BL, Wood P, Taran T, Leung M, Mueller KT, Zhang Y, Sen K, Lebwohl D, Pulsipher MA, Grupp SA |
| The New England journal of medicine. doi: 10.1056/NEJMoa1709866 |
| PMID: 29385370 |
| An effective modestly intensive re-induction regimen with bortezomib in relapsed or refractory paediatric acute lymphoblastic leukaemia. |
| Kaspers GJL, Niewerth D, Wilhelm BAJ, Scholte-van Houtem P, Lopez-Yurda M, Berkhof J, Cloos J, de Haas V, Mathôt RA, Attarbaschi A, Baruchel A, de Bont ES, Fagioli F, Rössig C, Klingebiel T, De Moerloose B, Nelken B, Palumbo G, Reinhardt D, Rohrlich PS, Simon P, von Stackelberg A, Zwaan MM |
| British journal of haematology. 2018 Apr 20. doi: 10.1111/bjh.15233 |
| PMID: 29676440 |
| Phase I dose-escalation study of volasertib in pediatric patients with acute leukemia or advanced solid tumors. |
| Doz F, Locatelli F, Baruchel A, Blin N, De Moerloose B, Frappaz D, Dworzak M, Fischer M, Stary J, Fuertig R, Riemann K, Taube T, Reinhardt D |
| Pediatric blood & cancer. 2019 Jul 5. doi: 10.1002/pbc.27900 |
| PMID: 31276318 |
| A Semi-Mechanistic Population Pharmacokinetic/Pharmacodynamic Model of Bortezomib in Pediatric Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia. |
| Janssen JM, Dorlo TPC, Niewerth D, Wilhelm AJ, Zwaan CM, Beijnen JH, Attarbaschi A, Baruchel A, Fagioli F, Klingebiel T, De Moerloose B, Palumbo G, von Stackelberg A, Kaspers GJL, Huitema ADR |
| Clinical pharmacokinetics. 2019 Jul 16. doi: 10.1007/s40262-019-00803-y. pii: 10.1007/s40262-019-00803-y |
| PMID: 31313068 |
| Patient-reported quality of life after tisagenlecleucel infusion in children and young adults with relapsed or refractory B-cell acute lymphoblastic leukaemia: a global, single-arm, phase 2 trial. |
| Laetsch TW, Myers GD, Baruchel A, Dietz AC, Pulsipher MA, Bittencourt H, Buechner J, De Moerloose B, Davis KL, Nemecek E, Driscoll T, Mechinaud F, Boissel N, Rives S, Bader P, Peters C, Sabnis HS, Grupp SA, Yanik GA, Hiramatsu H, Stefanski HE, Rasouliyan L, Yi L, Shah S, Zhang J, Harris AC |
| The Lancet. Oncology. 2019 Oct 9. pii: S1470-2045(19)30493-0. doi: 10.1016/S1470-2045(19)30493-0 |
| PMID: 31606419 |
| Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency. |
| Kozyra EJ, Pastor VB, Lefkopoulos S, Sahoo SS, Busch H, Voss RK, Erlacher M, Lebrecht D, Szvetnik EA, Hirabayashi S, Pasaulienė R, Pedace L, Tartaglia M, Klemann C, Metzger P, Boerries M, Catala A, Hasle H, de Haas V, Kállay K, Masetti R, De Moerloose B, Dworzak M, Schmugge M, Smith O, Starý J, Mejstrikova E, Ussowicz M, Morris E, Singh P, Collin M, Derecka M, Göhring G, Flotho C, Strahm B, Locatelli F, Niemeyer CM, Trompouki E, Wlodarski MW |
| Leukemia. 2020 Jun 18. doi: 10.1038/s41375-020-0899-5. pii: 10.1038/s41375-020-0899-5 |
| PMID: 32555368 |
| Features and outcome of chronic myeloid leukemia at very young age: Data from the International Pediatric Chronic Myeloid Leukemia Registry. |
| Meral Günes A, Millot F, Kalwak K, Lausen B, Sedlacek P, Versluys AB, Dworzak M, De Moerloose B, Suttorp M |
| Pediatric blood & cancer. 2020 Oct 8. doi: 10.1002/pbc.28706 |
| PMID: 33034135 |
| Hematopoietic stem cell transplantation in children and adolescents with GATA2-related myelodysplastic syndrome. |
| Bortnick R, Wlodarski M, de Haas V, De Moerloose B, Dworzak M, Hasle H, Masetti R, Starý J, Turkiewicz D, Ussowicz M, Kozyra E, Albert M, Bader P, Bordon V, Cario G, Beier R, Schulte J, Bresters D, Müller I, Pichler H, Sedlacek P, Sauer MG, Zecca M, Göhring G, Yoshimi A, Noellke P, Erlacher M, Locatelli F, Niemeyer CM, Strahm B |
| Bone marrow transplantation. 2021 Jul 9. doi: 10.1038/s41409-021-01374-y. pii: 10.1038/s41409-021-01374-y |
| PMID: 34244664 |
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