Zurück zur Übersicht
| The European respiratory journal. 2022 Aug 25. pii: 13993003.00469-2022. doi: 10.1183/13993003.00469-2022 |
| Association of respiratory symptoms and lung function with occupation in the multinational Burden of Obstructive Lung Disease (BOLD) study. |
| Ratanachina J1, Amaral AFS2, De Matteis S3, Lawin H4, Mortimer K5, Obaseki DO6, Harrabi I7, Denguezli M8, Wouters EFM9, Janson C10, Nielsen R11, Gulsvik A12, Hacene Cherkaski H13, Mejza F14, Padukudru Anand M15, Elsony A16, Ahmed R17, Tan W18, Li Cher L19, Rashid A20, Studnicka M21, Nafees AA22, Seemungal T23, Aquart-Stewart A24, Al Ghobain M25, Zheng J26, Juvekar S27, Salvi S28, Jogi R29, Mannino D30, Gislason T31, Buist AS32, Cullinan P33, Burney P34 |
 Author information
|
|
Abstract Chronic obstructive pulmonary disease has been associated with exposures in the workplace. We aimed to assess the association of respiratory symptoms and lung function with occupation in the Burden of Obstructive Lung Disease study. We analysed cross-sectional data from 28,823 adults (≥40 years) in 34 countries. Eleven occupations were considered and grouped by likelihood of exposure to organic dusts, inorganic dusts and fumes. The association of chronic cough, chronic phlegm, wheeze, dyspnoea, FEV1/FVC and FVC with occupation was assessed, per study site, using multivariable regression. These estimates were then meta-analysed. Sensitivity analyses explored differences between sexes and gross national income (GNI). Overall, working in settings with potentially high exposure to dusts or fumes was associated with respiratory symptoms but not lung function differences. The most common occupation was farming. Compared to people not working in any of the 11 considered occupations, those who were farmers for ≥20 years were more likely to have chronic cough (OR=1.52, 95%CI 1.19-1.94), wheeze (OR=1.37, 95%CI 1.16-1.63), and dyspnoea (OR=1.83, 95%CI 1.53-2.20), but not lower FVC (β=0.02L, 95%CI -0.02L to 0.06L) or lower FEV/FVC (β=0.04%, 95%CI -0.49% to 0.58%). Some findings differed by sex and GNI. In summary, at a population level, the occupational exposures considered in this study do not appear to be major determinants of differences in lung function, although they associate with more respiratory symptoms. As not all work settings were included in this study, respiratory surveillance should still be encouraged among high-risk dusty and fume job workers, especially in low- and middle-income countries. |
|
Copyright ©The authors 2022. |
|
Publikations ID: 36028253 Quelle: öffnen |
Author information
Schnellinfo
-- Cancer Care
-- Kliniken und Partner
-- CCC Cancer School
-- Young CCC
-- CCC Tumorboards
-- CCC Forschungscluster
-- CCC Units
-- CCC Platforms
-- SOPs / Leitlinien
-- Kontakt
Featured
