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    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 2020 Feb 20. pii: S0748-7983(20)30121-9. doi: 10.1016/j.ejso.2020.02.019
    Shanghai international consensus on diagnosis and comprehensive treatment of colorectal liver metastases (version 2019).
    Ren L1,  Zhu D2,  Benson AB3,  Nordlinger B4,  Koehne CH5,  Delaney CP6,  Kerr D7,  Lenz HJ8,  Fan J9,  Wang J10,  Gu J11,  Li J12,  Shen L13,  Tsarkov P14,  Tejpar S15,  Zheng S16,  Zhang S17,  Gruenberger T18,  Qin X19,  Wang X20,  Zhang Z21,  Poston GJ22,  Xu J23
    Collaborators
    Zhou A Parvaiz A Zhu A Eng C Lau CW Song C Tang CN Lynch C Wan D Loyer E Aucejo F Wang F Chang GJ Chen G Yang GZ Choi GS Wieshmann H Tulina I Oh JH Ngu JC Wang JY Zhou J Jin J Liang JT Wang J Kwak JM Okuda J Lee KY Ding K Kuo LJ Ito M Ohue M Zeng M Valente M Miyoshi N Bianchi PP Lan P Xu R Cai S Kim SH Wang S Zeng S Ng SS Krishnamurthi S Fenwick S Akiyoshi T Liu T Maughan T Konishi T Law WL Zhang W Sun W Chen WT Wang Y Wang Y Yuan Y Sun Y Hou Y You YN Lee YS Yao Y Liu Y Kinugasa Y Zhang Z Yan Z Pan Z Xu Z Zhou Z
    Author information
    1Department of Colorectal Surgery, Colorectal Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China.
    2Department of Colorectal Surgery, Colorectal Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China.
    3Division of Hematology/Oncology, Northwestern Medical Group, Chicago, USA.
    4Surgery Department, Hospital Ambroise-Pare, Boulogne-Billancourt, France.
    5Department of Oncology and Haematology, Klinikum Oldenburg, Oldenburg, Germany.
    6Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.
    7Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
    8Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
    9Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Fudan University, Shanghai, China.
    10Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
    11Department of Colorectal Surgery, Peking University Cancer Hospital, Beijing, China; Department of Colorectal Surgery, Peking University Shougang Hospital, Beijing, China.
    12Department of Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
    13Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital and Institute, Beijing, China.
    14Clinic of Colorectal and Minimally Invasive Surgery, Sechenov First Moscow State Medical University, Moscow, Russia.
    15Department of Gastroenterology, University Hospitals Leuven, Leuven, Belgium.
    16Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
    17Department of Surgical Oncology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
    18Department of Surgery, Rudolfstiftung Hospital, Vienna, Austria.
    19Department of Colorectal Surgery, Colorectal Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China.
    20Department of Colorectal Surgery, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
    21Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center of Digestive Diseases, Beijing, China.
    22Surgery Department, Aintree University Hospital, School of Translational Studies, University of Liverpool, Liverpool, UK. Electronic address: graemeposton@blueyonder.co.uk.
    23Department of Colorectal Surgery, Colorectal Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China. Electronic address: xujmin@aliyun.com.
    Abstract

    The liver is the most common anatomical site for hematogenous metastases from colorectal cancer. Therefore effective treatment of liver metastases is one of the most challenging elements in the management of colorectal cancer. However, there is rare available clinical consensus or guideline only focusing on colorectal liver metastases. After six rounds of discussion by 195 clinical experts of the Shanghai International Consensus Expert Group on Colorectal Liver Metastases (SINCE) from 29 countries or regions, the Shanghai Consensus has been finally completed, based on current research and expert experience. The consensus emphasized the principle of multidisciplinary team, provided detailed diagnosis approaches, and guided precise local and systemic treatments. This Shanghai Consensus might be of great significance to standardized diagnosis and treatment of colorectal liver metastases all over the world.


    Copyright © 2020 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

    KEYWORDS: Colorectal liver metastases, Comprehensive therapy, Diagnosis, Multidisciplinary team

    Publikations ID: 32147426
    Quelle: öffnen
     
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