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    Current biology : CB. 2019 Jan 10. pii: S0960-9822(18)31609-9. doi: 10.1016/j.cub.2018.12.008. pmc: PMC6345625
    The Genomic Footprints of the Fall and Recovery of the Crested Ibis.
    Feng S1,  Fang Q2,  Barnett R3,  Li C4,  Han S5,  Kuhlwilm M6,  Zhou L7,  Pan H8,  Deng Y9,  Chen G10,  Gamauf A11,  Woog F12,  Prys-Jones R13,  Marques-Bonet T14,  Gilbert MTP15,  Zhang G16
    Author information
    1University of Chinese Academy of Sciences, Beijing 100049, China; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China; China National GeneBank, BGI-Shenzhen, Shenzhen 518083, China.
    2China National GeneBank, BGI-Shenzhen, Shenzhen 518083, China; Section for Ecology and Evolution, Department of Biology, University of Copenhagen, DK-2100 Copenhagen, Denmark.
    3Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, 1350 Copenhagen, Denmark.
    4China National GeneBank, BGI-Shenzhen, Shenzhen 518083, China; The Francis Crick Institute, London NW1 1AT, UK.
    5Institute of Evolutionary Biology (UPF-CSIC), PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.
    6Institute of Evolutionary Biology (UPF-CSIC), PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.
    7China National GeneBank, BGI-Shenzhen, Shenzhen 518083, China.
    8China National GeneBank, BGI-Shenzhen, Shenzhen 518083, China; Section for Ecology and Evolution, Department of Biology, University of Copenhagen, DK-2100 Copenhagen, Denmark.
    9China National GeneBank, BGI-Shenzhen, Shenzhen 518083, China.
    10University of Chinese Academy of Sciences, Beijing 100049, China; China National GeneBank, BGI-Shenzhen, Shenzhen 518083, China.
    11Museum of Natural History Vienna, 1st Zoological Department - Ornithology, Burgring 7, A-1010 Vienna, Austria.
    12Staatliches Museum für Naturkunde, Rosenstein 1, 70191 Stuttgart, Germany.
    13Bird Group, Department of Life Sciences, Natural History Museum, Akeman St, Tring, Herts HP23 6AP, UK.
    14Institute of Evolutionary Biology (UPF-CSIC), PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain; Catalan Institution of Research and Advanced Studies (ICREA), Passeig de Lluís Companys, 23, 08010, Barcelona, Spain; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Baldiri i Reixac 4, 08028 Barcelona, Spain; Institut Català de Paleontologia Miquel Crusafont, Universitat Autònoma de Barcelona, Edifici ICTA-ICP, c/ Columnes s/n, 08193 Cerdanyola del Vallès, Barcelona, Spain.
    15Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, 1350 Copenhagen, Denmark; Norwegian University of Science and Technology, University Museum, 7491 Trondheim, Norway.
    16State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China; China National GeneBank, BGI-Shenzhen, Shenzhen 518083, China; Section for Ecology and Evolution, Department of Biology, University of Copenhagen, DK-2100 Copenhagen, Denmark; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming 650223, China. Electronic address: guojie.zhang@bio.ku.dk.
    Abstract

    Human-induced environmental change and habitat fragmentation pose major threats to biodiversity and require active conservation efforts to mitigate their consequences. Genetic rescue through translocation and the introduction of variation into imperiled populations has been argued as a powerful means to preserve, or even increase, the genetic diversity and evolutionary potential of endangered species [1-4]. However, factors such as outbreeding depression [5, 6] and a reduction in available genetic diversity render the success of such approaches uncertain. An improved evaluation of the consequence of genetic restoration requires knowledge of temporal changes to genetic diversity before and after the advent of management programs. To provide such information, a growing number of studies have included small numbers of genomic loci extracted from historic and even ancient specimens [7, 8]. We extend this approach to its natural conclusion, by characterizing the complete genomic sequences of modern and historic population samples of the crested ibis (Nipponia nippon), an endangered bird that is perhaps the most successful example of how conservation effort has brought a species back from the brink of extinction. Though its once tiny population has today recovered to >2,000 individuals [9], this process was accompanied by almost half of ancestral loss of genetic variation and high deleterious mutation load. We furthermore show how genetic drift coupled to inbreeding following the population bottleneck has largely purged the ancient polymorphisms from the current population. In conclusion, we demonstrate the unique promise of exploiting genomic information held within museum samples for conservation and ecological research.


    Copyright © 2018 The Author(s). Published by Elsevier Ltd.. All rights reserved.

    KEYWORDS: ancient genomics, conservation genomics, demography, endangered species, extinction, genetic recovery, inbreeding, mutation load, ornithology, population genomics

    Publikations ID: 30639104
    Quelle: öffnen
     
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