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| Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 2016 Jul 5. pii: mdw235. doi: 10.1093/annonc/mdw235 |
| ESMO consensus guidelines for the management of patients with metastatic colorectal cancer. |
| Van Cutsem E1, Cervantes A2, Adam R3, Sobrero A4, Van Krieken JH5, Aderka D6, Aranda Aguilar E7, Bardelli A8, Benson A9, Bodoky G10, Ciardiello F11, D'Hoore A12, Diaz-Rubio E13, Douillard JY14, Ducreux M15, Falcone A16, Grothey A17, Gruenberger T18, Haustermans K19, Heinemann V20, Hoff P21, Köhne CH22, Labianca R23, Laurent-Puig P24, Ma B25, Maughan T26, Muro K27, Normanno N28, Österlund P29, Oyen WJ30, Papamichael D31, Pentheroudakis G32, Pfeiffer P33, Price TJ34, Punt C35, Ricke J36, Roth A37, Salazar R38, Scheithauer W39, Schmoll HJ40, Tabernero J41, Taïeb J42, Tejpar S43, Wasan H44, Yoshino T45, Zaanan A46, Arnold D47 |
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Abstract Colorectal cancer (CRC) is one of the most common malignancies in Western countries. Over the last 20 years, and the last decade in particular, the clinical outcome for patients with metastatic CRC (mCRC) has improved greatly due not only to an increase in the number of patients being referred for and undergoing surgical resection of their localised metastatic disease but also to a more strategic approach to the delivery of systemic therapy and an expansion in the use of ablative techniques. This reflects the increase in the number of patients that are being managed within a multidisciplinary team environment and specialist cancer centres, and the emergence over the same time period not only of improved imaging techniques but also prognostic and predictive molecular markers. Treatment decisions for patients with mCRC must be evidence-based. Thus, these ESMO consensus guidelines have been developed based on the current available evidence to provide a series of evidence-based recommendations to assist in the treatment and management of patients with mCRC in this rapidly evolving treatment setting. |
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© The Author 2016. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oup.com. |
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KEYWORDS: ESMO, clinical practice guidelines, colorectal cancer, consensus |
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Publikations ID: 27380959 Quelle: öffnen |
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