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| Hematology/oncology clinics of North America. 2014 Dec 17. pii: S0889-8588(14)00144-0. doi: 10.1016/j.hoc.2014.10.003 |
| Diagnosis and management of upper tract urothelial carcinoma. |
| Lucca I1, Leow JJ2, Shariat SF3, Chang SL4 |
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Abstract While UTUC is relatively uncommon, it has an aggressive natural history and poor prognosis, which has not substantially improved over the past two decades. Nevertheless, continued research has led to the discovery of risk factors improving the prevention and early detection of UTUC. Although RNU remains the standard treatment for localized invasive UTUC, nephron-sparing surgery for selected patients has made considerable progress in the recent years. The stagnation in the prognosis of UTUC over the past two decades highlights the necessity for incorporating multimodal approaches including refinements in systemic chemotherapy and radiotherapy to attain better outcomes for patients with UTUC. |
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Copyright © 2015 Elsevier Inc. All rights reserved. |
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KEYWORDS: Chemotherapy, Kidney neoplasms, Nephroureterectomy, Radiotherapy, Upper tract urothelial carcinoma, Ureteral neoplasms, Urothelial carcinoma |
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Publikations ID: 25836934 Quelle: öffnen |
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