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    Clinical imaging. 2014 Nov 18. pii: S0899-7071(14)00271-X. doi: 10.1016/j.clinimag.2014.11.003
    4D co-registration of X-ray and MR-mammograms: initial clinical results and potential incremental diagnostic value.
    Dietzel M1,  Hopp T2,  Ruiter NV3,  Kaiser CG4,  Kaiser WA5,  Baltzer PA6
    Author information
    1Department of Neuroradiology, University of Erlangen-Nürnberg, Schwabachanlage 6, D-91054, Germany; Institute of Diagnostic and Interventional Radiology I, Friedrich-Schiller-University Jena, Erlanger Allee 101, D-07740 Jena, Germany. Electronic address: dietzelmatthias2@hotmail.com.
    2Karlsruhe Institute of Technology (KIT), Institute for Data Processing and Electronics, Postfach 3640, D-76021 Karlsruhe, Germany.
    3Karlsruhe Institute of Technology (KIT), Institute for Data Processing and Electronics, Postfach 3640, D-76021 Karlsruhe, Germany.
    4Institute of Diagnostic and Interventional Radiology I, Friedrich-Schiller-University Jena, Erlanger Allee 101, D-07740 Jena, Germany; Karlsruhe Institute of Technology (KIT), Institute for Data Processing and Electronics, Postfach 3640, D-76021 Karlsruhe, Germany.
    5Institute of Diagnostic and Interventional Radiology I, Friedrich-Schiller-University Jena, Erlanger Allee 101, D-07740 Jena, Germany.
    6Institute of Diagnostic and Interventional Radiology I, Friedrich-Schiller-University Jena, Erlanger Allee 101, D-07740 Jena, Germany; Institute of Clinical Radiology and Nuclear Medicine, University Medical Centre Mannheim, Medical Faculty Mannheim-University of Heidelberg, Theodor-Kutzer-Ufer 1-3, Mannheim Jena, Germany; Department of Biomedical Imaging and Image-guided therapy, Vienna.
    Abstract

    PURPOSE: 4D co-registration of X-ray- and MR-mammograms (XM and MM) is a new method of image fusion. The present study aims to evaluate its clinical feasibility, radiological accuracy, and potential clinical value.

    METHODS: XM and MM of 25 patients were co-registered. Results were evaluated by a blinded reader.

    RESULTS: Precision of the 4D co-registration was "very good" (mean-score [ms]=7), and lesions were "easier to delineate" (ms=5). In 88.8%, "relevant additional diagnostic information" was present, accounting for a more "confident diagnosis" in 76% (ms=5).

    CONCLUSION: 4D co-registration is feasible, accurate, and of potential clinical value.


    Copyright © 2015 Elsevier Inc. All rights reserved.

    KEYWORDS: Co-registration, Dynamic contrast enhanced MRI, Mammography, Multimodal diagnosis

    Publikations ID: 25537430
    Quelle: öffnen
     
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